Carbapenems

scientific article

Carbapenems is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1179/1973947812Y.0000000032
P3181OpenCitations bibliographic resource ID4643657
P698PubMed publication ID23433439
P5875ResearchGate publication ID235714895

P50authorBernard AllaouchicheQ88620770
P2093author name stringDominique Breilh
Emmanuel Boselli
Jeannette Texier-Maugein
Marie-Claude Saux
P2860cites workMeropenem versus imipenem/cilastatin in intra-abdominal infections requiring surgery. Meropenem Study Group.Q54005690
Meropenem versus imipenem/cilastatin in the treatment of intra-abdominal infections.Q54017571
Clinical evaluation of meropenem versus ceftazidime for the treatment of Pseudomonas spp. infections in cystic fibrosis patients.Q54168335
Effects of clinical breakpoint changes in CLSI guidelines 2010/2011 and EUCAST guidelines 2011 on antibiotic susceptibility test reporting of Gram-negative bacilli.Q54346349
Ertapenem versus ceftriaxone and metronidazole as treatment for complicated intra-abdominal infections.Q54442418
Randomized, multicenter, double-blind study of efficacy, safety, and tolerability of intravenous ertapenem versus piperacillin/tazobactam in treatment of complicated intra-abdominal infections in hospitalized adults.Q54444593
Efficacy and safety of ertapenem versus piperacillin-tazobactam for the treatment of intra-abdominal infections requiring surgical intervention.Q54466586
Carbapenems: past, present, and futureQ24634999
Carbapenemases: the versatile beta-lactamasesQ24685034
Overview of seizure-inducing potential of doripenemQ28254469
Clinical review: balancing the therapeutic, safety, and economic issues underlying effective antipseudomonal carbapenem useQ28299749
Results of a clinical trial of clinafloxacin versus imipenem/cilastatin for intraabdominal infectionsQ28345630
Treatment of severe pneumonia in hospitalized patients: results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin. The Severe Pneumonia Study Group.Q33751215
Pharmacokinetics and pharmacodynamics of imipenem during continuous renal replacement therapy in critically ill patientsQ33836550
Comparative pharmacokinetics of the carbapenems: clinical implicationsQ34053776
Pharmacokinetics of meropenem in patients with renal failure and patients receiving renal replacement therapyQ34078480
Ertapenem versus ceftriaxone followed by appropriate oral therapy for treatment of complicated urinary tract infections in adults: results of a prospective, randomized, double-blind multicenter studyQ34112476
Pharmacokinetics of ertapenem in healthy young volunteers.Q34141850
Ertapenem versus piperacillin/tazobactam for diabetic foot infections (SIDESTEP): prospective, randomised, controlled, double-blinded, multicentre trial.Q34468030
Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trialsQ34475273
Structural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C beta-lactamaseQ34522266
Multiplex real-time PCR assay for detection and classification of Klebsiella pneumoniae carbapenemase gene (bla KPC) variantsQ34596735
Tissue penetration by ertapenem, a parenteral carbapenem administered once daily, in suction-induced skin blister fluid in healthy young volunteersQ34883132
Treatment of severe nosocomial pneumonia: a prospective randomised comparison of intravenous ciprofloxacin with imipenem/cilastatinQ35533543
Bactericidal activities of meropenem and ertapenem against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a neutropenic mouse thigh modelQ35758849
Newer carbapenems for urinary tract infectionsQ35885913
Relationship of minimal inhibitory concentration and bactericidal activity to efficacy of antibiotics for treatment of ventilator-associated pneumoniaQ36410139
Comparative review of the carbapenemsQ36815085
Cefepime versus imipenem-cilastatin for treatment of nosocomial pneumonia in intensive care unit patients: a multicenter, evaluator-blind, prospective, randomized studyQ36880729
Continuous infusion of beta-lactams.Q36924963
Carbapenems in the USA: focus on doripenemQ36960048
In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group.Q36993524
Carbapenems: a potent class of antibioticsQ37030838
Parenteral carbapenemsQ37043637
Comparative activities of doripenem versus isolates, mutants, and transconjugants of Enterobacteriaceae and Acinetobacter spp. with characterized beta-lactamasesQ37120635
In vitro antimicrobial activity of doripenem, a new carbapenemQ37121257
Doripenem: a review of its use in the treatment of bacterial infections.Q37263205
Intravenous doripenem at 500 milligrams versus levofloxacin at 250 milligrams, with an option to switch to oral therapy, for treatment of complicated lower urinary tract infection and pyelonephritisQ37333147
New developments in carbapenemsQ37348751
Pharmacokinetic issues for antibiotics in the critically ill patientQ37399820
Doripenem monohydrate, a broad-spectrum carbapenem antibioticQ37401472
Activity of a novel carbapenem, doripenem, against anaerobic pathogensQ37403090
Doripenem: position in clinical practiceQ37503320
Rapid evolution and spread of carbapenemases among Enterobacteriaceae in EuropeQ38002952
In vitro activities of ertapenem (MK-0826) against recent clinical bacteria collected in Europe and AustraliaQ39477537
An overview of the pharmacology of imipenem/cilastatinQ39758549
Meropenem pharmacokinetics and penetration into an inflammatory exudateQ39816570
Multiple-dose pharmacokinetics of imipenem-cilastatinQ39849277
Pharmacokinetic-pharmacodynamic-model-guided doripenem dosing in critically ill patientsQ40749626
Is continuous infusion of beta-lactam antibiotics worthwhile?--efficacy and pharmacokinetic considerationsQ41153161
Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men.Q41696128
Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysisQ41912139
Characteristics of doripenem: a new broad-spectrum antibioticQ42049594
Optimal meropenem concentrations to treat multidrug-resistant Pseudomonas aeruginosa septic shockQ42558993
Diffusion of ertapenem into bone and synovial tissues.Q42629280
A Multicenter Comparative Study of Meropenem and Imipenem/Cilastatin in the Treatment of Complicated Urinary Tract Infections in Hospitalized PatientsQ42677494
Affinity of doripenem and comparators to penicillin-binding proteins in Escherichia coli and Pseudomonas aeruginosaQ43111763
Penetration of doripenem into prostatic tissue following intravenous administration in prostatectomy patientsQ43147926
Relevance of resistance levels to carbapenems and integron-borne blaIMP-1, blaIMP-7, blaIMP-10 and blaVIM-2 in clinical isolates of Pseudomonas aeruginosaQ43168664
Disposition, metabolism, and excretion of [14C]doripenem after a single 500-milligram intravenous infusion in healthy men.Q43190490
Doripenem pharmacokinetics in critically ill patients receiving continuous hemodiafiltration (CHDF).Q43203100
Combined imipenem/cilastatin and tobramycin therapy of multiresistant Pseudomonas aeruginosa in cystic fibrosisQ43580816
A prospective, multicenter, randomized, double-blind study comparing ertapenem and ceftriaxone followed by appropriate oral therapy for complicated urinary tract infections in adultsQ43595316
Meropenem and continuous renal replacementQ43707193
Tissue penetration of Meropenem in patients undergoing gynecologic surgeryQ43743957
Piperacillin 2 g/tazobactam 0.5 g is as effective as imipenem 0.5 g/cilastatin 0.5 g for the treatment of acute uncomplicated pyelonephritis and complicated urinary tract infectionsQ43890461
A study evaluating the efficacy, safety, and tolerability of ertapenem versus ceftriaxone for the treatment of community-acquired pneumonia in adultsQ43933899
Ertapenem once daily versus piperacillin-tazobactam 4 times per day for treatment of complicated skin and skin-structure infections in adults: results of a prospective, randomized, double-blind multicenter studyQ43996920
Comparative in-vitro activities of ertapenem against aerobic bacterial pathogens isolated from patients with complicated intra-abdominal infectionsQ44066002
Ertapenem monotherapy versus combination therapy with ceftriaxone plus metronidazole for treatment of complicated intra-abdominal infections in adultsQ44183675
A prospective, randomized, double-blind multicenter comparison of parenteral ertapenem and ceftriaxone for the treatment of hospitalized adults with community-acquired pneumoniaQ44261936
Antimicrobial-induced release of endotoxin from Pseudomonas aeruginosa: comparison of in vitro and animal modelsQ44299887
Carbapenems in the treatment of severe community-acquired pneumonia in hospitalized elderly patients: a comparative study against standard therapyQ44312895
Antibiotic monotherapy with meropenem in the surgical management of intra-abdominal infectionsQ44404714
Levofloxacin compared with imipenem/cilastatin followed by ciprofloxacin in adult patients with nosocomial pneumonia: A multicenter, prospective, randomized, open-label studyQ44442591
The pharmacokinetics and pharmacodynamics of meropenem in the cerebrospinal fluid of neurosurgical patientsQ44736207
In vitro killing of parenteral beta-lactams against standard and high inocula of extended-spectrum beta-lactamase and non-ESBL producing Klebsiella pneumoniaeQ44890369
Doripenem (S-4661), a novel carbapenem: comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluationsQ44931240
Comparative disposition of [14C]ertapenem, a novel carbapenem antibiotic, in rat, monkey and man.Q44989494
Antimicrobial resistance rates and clonality results from the Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) programme: report of year five (2003).Q45020140
Doripenem.Q45968844
Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK.Q46113955
Ertapenem peritoneal fluid concentrations in adult surgical patientsQ46189699
In vitro activity of doripenem against Acinetobacter baumannii clinical isolatesQ46269429
Meta-analysis of the clinical outcome of carbapenem monotherapy in the adjunctive treatment of intra-abdominal infectionsQ46350390
Pharmacokinetic evaluation of meropenem and imipenem in critically ill patients with sepsisQ46472365
Penetration of ertapenem into different pulmonary compartments of patients undergoing lung surgeryQ46497112
Efficacy and tolerability of IV doripenem versus meropenem in adults with complicated intra-abdominal infection: a phase III, prospective, multicenter, randomized, double-blind, noninferiority studyQ46538480
Meropenem versus imipenem-cilastatin for the treatment of hospitalized patients with complicated skin and skin structure infections: results of a multicenter, randomized, double-blind comparative studyQ46733446
Meta-analysis: ertapenem for complicated intra-abdominal infections.Q46759587
The efficacy and safety of meropenem and tobramycin vs ceftazidime and tobramycin in the treatment of acute pulmonary exacerbations in patients with cystic fibrosisQ46763845
Intrapulmonary pharmacokinetics and pharmacodynamics of meropenemQ46798613
Antimicrobial activity of doripenem (S-4661): a global surveillance report (2003).Q46819792
Intraabdominal tissue concentration of ertapenemQ46882391
Meropenem by continuous versus intermittent infusion in ventilator-associated pneumonia due to gram-negative bacilliQ46921577
Meropenem activity against European isolates: report on the MYSTIC (Meropenem Yearly Susceptibility Test Information Collection) 2006 resultsQ46942931
Comparison of piperacillin/tazobactam and imipenem/cilastatin, both in combination with tobramycin, administered every 6 h for treatment of nosocomial pneumoniaQ46951637
Peritoneal penetration of doripenem after intravenous administration in abdominal-surgery patientsQ46989475
Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibioticsQ48611808
Pneumonia: the impact of risk factors on the outcome of treatment with meropenem and ceftazidime.Q50898088
Ertapenem in critically ill patients with early-onset ventilator-associated pneumonia: pharmacokinetics with special consideration of free-drug concentration.Q51926298
The utility of diffusion chambers as models for the description of drug disposition.Q52429191
Meropenem (1.5 g/day) is as effective as imipenem/cilastatin (2 g/day) for the treatment of moderately severe intra-abdominal infections.Q53933241
Meropenem monotherapy versus cefotaxime plus metronidazole combination treatment for serious intra-abdominal infections.Q53979811
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcarbapenem antibioticQ410897
P304page(s)1-17
P577publication date2013-02-01
P1433published inJournal of ChemotherapyQ15754073
P1476titleCarbapenems
P478volume25

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main subject (P921)
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