Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells

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Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1053325931
P356DOI10.1038/ONC.2010.290
P3181OpenCitations bibliographic resource ID4713073
P698PubMed publication ID20661218
P5875ResearchGate publication ID45366823

P2093author name stringJ Yuan
A Krämer
K Strebhardt
K Sommer
F Rödel
M Sanhaji
N N Kreis
P2860cites workThe HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53Q24317677
Activation of p53 in cervical carcinoma cells by small molecules.Q24644964
Surfing the p53 networkQ28032484
Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cellsQ28267868
Stable gene silencing of cyclin B1 in tumor cells increases susceptibility to taxol and leads to growth arrest in vivoQ28281137
Live or let die: the cell's response to p53Q29547663
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53Q29547773
Regulating the p53 pathway: in vitro hypotheses, in vivo veritasQ29615658
Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxolQ30856412
Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2Q33643799
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.Q33889383
Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3betaQ34097322
Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinasesQ34298718
Awakening guardian angels: drugging the p53 pathwayQ35014385
INK4a/ARF: a multifunctional tumor suppressor locusQ36119162
The ARF tumour suppressorQ36442822
The complexity of p53 stabilization and activationQ36443523
Living with p53, dying of p53.Q36919156
Short version of the German evidence-based Guidelines for prophylactic vaccination against HPV-associated neoplasiaQ37518473
Phosphorylation studies on rat p53 using the baculovirus expression system. Manipulation of the phosphorylation state with okadaic acid and influence on DNA bindingQ38297617
Functional and spatial regulation of mitotic centromere-associated kinesin by cyclin-dependent kinase 1.Q39718774
E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cellsQ39874615
Elevation of cyclin B1, active cdc2, and HuR in cervical neoplasia with human papillomavirus type 18 infection.Q40320764
Flavopiridol induces p53 via initial inhibition of Mdm2 and p21 and, independently of p53, sensitizes apoptosis-reluctant cells to tumor necrosis factorQ40554349
Nucleophosmin (B23) targets ARF to nucleoli and inhibits its functionQ41036948
Activation of p53 by roscovitine-mediated suppression of MDM2 expressionQ43652194
Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21(WAF1/CIP1).Q44325791
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.Q45345467
CDK9 phosphorylates p53 on serine residues 33, 315 and 392Q82904823
P433issue41
P407language of work or nameEnglishQ1860
P921main subjecthuman papillomavirus 16Q69461345
P304page(s)5591-603
P577publication date2010-10-14
P1433published inOncogeneQ1568657
P1476titleRestoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells
P478volume29

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