The novel oncogene CD24 and its arising role in the carcinogenesis of the GI tract: from research to therapy

scientific article

The novel oncogene CD24 and its arising role in the carcinogenesis of the GI tract: from research to therapy is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1586/17474124.2.1.125
P3181OpenCitations bibliographic resource ID942159
P698PubMed publication ID19072375

P2093author name stringNadir Arber
Eyal Sagiv
P2860cites workCD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling systemQ24291153
CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cellsQ24300245
Association of CD24 with the kinase c-fgr in a small cell lung cancer cell line and with the kinase lyn in an erythroleukemia cell lineQ24315638
Prospective identification of tumorigenic breast cancer cellsQ24683474
A genetic model for colorectal tumorigenesisQ27860582
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cellQ27861001
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumoursQ28206040
Mapping of CD24 and homologous sequences to multiple chromosomal lociQ28240706
Identification of pancreatic cancer stem cellsQ28286997
A dinucleotide deletion in CD24 confers protection against autoimmune diseasesQ28469176
Heat-stable antigen (CD24) as ligand for mouse P-selectinQ28506774
Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectinQ28586074
Cross-linking the murine heat-stable antigen induces apoptosis in B cell precursors and suppresses the anti-CD40-induced proliferation of mature resting B lymphocytesQ28586162
The neural recognition molecule L1 is a sialic acid-binding lectin for CD24, which induces promotion and inhibition of neurite outgrowthQ28588696
Differential mRNA display analysis of two related but functionally distinct rat insulinoma (RIN) cell lines: identification of CD24 and its expression in the developing pancreasQ28589592
Differential, LFA-1-sensitive effects of antibodies to nectadrin, the heat-stable antigen, on B lymphoblast aggregation and signal transductionQ28593239
The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiationQ29620694
The metastasis-associated gene CD24 is regulated by Ral GTPase and is a mediator of cell proliferation and survival in human cancerQ30439590
Characterization of prostate cell types by CD cell surface moleculesQ30795292
N-glycosylation patterns of HSA/CD24 from different cell lines and brain homogenates: a comparisonQ30953954
CD24 is a genetic modifier for risk and progression of multiple sclerosis.Q34390318
Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancerQ34652960
Mucin-type O-glycans in human colon and breast cancer: glycodynamics and functionsQ34683362
Isolation and functional characterization of murine prostate stem cellsQ35250689
CD24 is expressed in ovarian cancer and is a new independent prognostic marker of patient survival.Q35789342
Tumour biological aspects of CD24, a mucin-like adhesion moleculeQ35875575
Selective cytotoxic effects of a ricin A chain immunotoxin made with the monoclonal antibody SWA11 recognising a human small cell lung cancer antigenQ35981940
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrowQ36230070
P-selectin deficiency attenuates tumor growth and metastasisQ36257237
L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancersQ36321410
CD24 and human carcinoma: tumor biological aspectsQ36409389
Selectins--potential pharmacological targets?Q36630618
CD24 is an independent prognostic marker of survival in nonsmall cell lung cancer patients.Q38307469
CD24 induces localization of beta1 integrin to lipid raft domainsQ40057453
CD24 is a new oncogene, early at the multistep process of colorectal cancer carcinogenesisQ40246991
CD24 plays an important role in the carcinogenesis process of the pancreasQ40258226
CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasisQ40345092
Cytoplasmic CD24 expression in colorectal cancer independently correlates with shortened patient survivalQ40372719
CD24 is a marker for human breast carcinomaQ40932675
The 5'-flanking region of human CD24 gene has cell-type-specific promoter activity in small-cell lung cancerQ40997940
The small cell lung cancer antigen cluster-4 and the leukocyte antigen CD24 are allelic isoforms of the same gene (CD24) on chromosome band 6q21.Q41395035
Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomasQ41603218
CD24 expression is a significant predictor of PSA relapse and poor prognosis in low grade or organ confined prostate cancer.Q47272085
Pretherapeutic identification of high‐risk acute myeloid leukemia (AML) patients from immunophenotypic, cytogenetic, and clinical parametersQ47949413
The heat stable antigen (CD24) is not required for the generation of CD4+ effector and memory T cells by dendritic cells in vivo.Q51998972
Localization of the gene for familial adenomatous polyposis on chromosome 5.Q52255517
Expression of CD24 in adenocarcinomas of the pancreas correlates with higher tumor grades.Q52943896
Association of aCD24 gene polymorphism with susceptibility to systemic lupus erythematosusQ57307107
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcarcinogenesisQ1637543
P304page(s)125-33
P577publication date2008-02-01
P1433published inExpert Review of Gastroenterology & HepatologyQ15733730
P1476titleThe novel oncogene CD24 and its arising role in the carcinogenesis of the GI tract: from research to therapy
P478volume2

Reverse relations

cites work (P2860)
Q35715553Adipose tissue stem cells meet preadipocyte commitment: going back to the future
Q38089897Blood-based peptide, genetic, and epigenetic biomarkers for diagnosing gastrointestinal cancers
Q83005419CD24 and galectin-1 expressions in gastric adenocarcinoma and clinicopathologic significance
Q35830525CD24 expression as a marker for predicting clinical outcome in human gliomas
Q30418726CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated
Q39026716CD24 knockout prevents colorectal cancer in chemically induced colon carcinogenesis and in APC(Min)/CD24 double knockout transgenic mice
Q37688297CD24 promoted cancer cell angiogenesis via Hsp90-mediated STAT3/VEGF signaling pathway in colorectal cancer
Q38816567CD24 promotes HCC progression via triggering Notch-related EMT and modulation of tumor microenvironment
Q50127899CD44/CD24 and aldehyde dehydrogenase 1 in estrogen receptor-positive early breast cancer treated with tamoxifen: CD24 positivity is a poor prognosticator.
Q84453489Clinicopathologic and prognostic significance of CD24 in gallbladder carcinoma
Q51067523Expression of CD24 and Siglec-10 in first trimester placenta: implications for immune tolerance at the fetal-maternal interface.
Q35758449Expression of L1 protein correlates with cluster of differentiation 24 and integrin β1 expression in gastrointestinal stromal tumors
Q53287216Gene expression following exposure to celecoxib in humans: pathways of inflammation and carcinogenesis are activated in tumors but not normal tissues.
Q48123419Impaired bone healing at tooth extraction sites in CD24-deficient mice: A pilot study
Q61711516Minor salivary glands of the lips: a novel, easily accessible source of potential stem/progenitor cells
Q34279411Mullerian inhibiting substance preferentially inhibits stem/progenitors in human ovarian cancer cell lines compared with chemotherapeutics
Q33933777NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expression
Q51180773Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis.
Q37725990Targeted immunotherapy for colorectal cancer: monoclonal antibodies and immunotoxins
Q28550137Terpinen-4-ol: A Novel and Promising Therapeutic Agent for Human Gastrointestinal Cancers
Q39241439The CD24 protein inducible expression system is an ideal tool to explore the potential of CD24 as an oncogene and a target for immunotherapy in vitro and in vivo.
Q38884858Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity
Q33276466UM-Chor1: establishment and characterization of the first validated clival chordoma cell line

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