| scholarly article | Q13442814 |
| P356 | DOI | 10.1023/A:1015810312465 |
| P8608 | Fatcat ID | release_hurgpkdbdzhqbf5x4ra2d352va |
| P3181 | OpenCitations bibliographic resource ID | 2221706 |
| P698 | PubMed publication ID | 1608900 |
| P2093 | author name string | R H Guy | |
| R O Potts | |||
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| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 663-9 | |
| P577 | publication date | 1992-05-01 | |
| P1433 | published in | Pharmaceutical Research | Q7180737 |
| P1476 | title | Predicting skin permeability | |
| P478 | volume | 9 |
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| Q51919692 | A quantitative structure-activity relationship (QSAR) study of dermal absorption using theoretical molecular descriptors. |
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| Q64922815 | A simple model for the prediction of corneal permeability. |
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| Q33757673 | A skin permeability model of insulin in the presence of chemical penetration enhancer |
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| Q45255508 | A surrogate for topical delivery in human skin: silicone membranes. |
| Q23923862 | A system coefficient approach for quantitative assessment of the solvent effects on membrane absorption from chemical mixtures |
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| Q34069196 | Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections |
| Q23915997 | Acute treatment with kerosene damages the dermal barrier and alters the distribution of topically applied benzo(a)pyrene in mice |
| Q90633024 | Adenosine Derivates as Antioxidant Agents: Synthesis, Characterization, in Vitro Activity, and Theoretical Insights |
| Q28534724 | AfroDb: a select highly potent and diverse natural product library from African medicinal plants |
| Q89762150 | Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities |
| Q45960774 | An evaluation of the potential of linear and nonlinear skin permeation models for the prediction of experimentally measured percutaneous drug absorption. |
| Q23923931 | An experimentally based approach for predicting skin permeability of chemicals and drugs using a membrane-coated fiber array |
| Q52254823 | An explanation for the variation of the sonophoretic transdermal transport enhancement from drug to drug. |
| Q30317740 | An in silico evaluation of the ADMET profile of the StreptomeDB database |
| Q26852656 | An integrated approach to optimizing skin delivery of cosmetic and pharmaceutical actives |
| Q33300104 | An integrated pharmacokinetic and imaging evaluation of vehicle effects on solute human epidermal flux and, retention characteristics |
| Q46253934 | An investigation into the influence of binary drug solutions upon diffusion and partition processes in model membranes |
| Q33825850 | Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment. |
| Q23913349 | Application of numerical methods for diffusion-based modeling of skin permeation |
| Q23913347 | Application of solid-phase microextraction to in vitro skin permeation experiments: example using diethyl phthalate |
| Q37264403 | Approaches for evaluating the relevance of multiroute exposures in establishing guideline values for drinking water contaminants |
| Q44940768 | Aqueous pathways dominate permeation of solutes across Pisum sativum seed coats and mediate solute transport via diffusion and bulk flow of water |
| Q58862110 | Assessing the pharmacokinetic profile of the CamMedNP natural products database: an in silico approach |
| Q40042963 | Assessing the safety of cosmetic chemicals: Consideration of a flux decision tree to predict dermally delivered systemic dose for comparison with oral TTC (Threshold of Toxicological Concern). |
| Q39721162 | Assessment of penetrant and vehicle mixture properties on transdermal permeability using a mixed effect pharmacokinetic model of ex vivo porcine skin. |
| Q38222548 | Assessment of the skin sensitising potency of the lower alkyl methacrylate esters |
| Q37024906 | Assessment of user safety, exposure and risk to veterinary medicinal products in the European Union |
| Q47724963 | Binding affinity and decontamination of dermal decontamination gel to model chemical warfare agent simulants. |
| Q33195506 | Biopartitioning micellar chromatography to predict skin permeability. |
| Q35589752 | Biopartitioning micellar separation methods: modelling drug absorption |
| Q86277668 | Can acute dermal systemic toxicity tests be replaced with oral tests? A comparison of route-specific systemic toxicity and hazard classifications under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) |
| Q50599367 | Carbon nanotube membranes to predict skin permeability of compounds. |
| Q35999189 | Characterization of the permeability barrier of human skin in vivo |
| Q57928737 | Chemical Enhancer: A Simplistic Way to Modulate Barrier Function of the Stratum Corneum |
| Q33637376 | Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations |
| Q42181033 | Chemical enhancer solubility in human stratum corneum lipids and enhancer mechanism of action on stratum corneum lipid domain. |
| Q37191669 | Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster cheek pouch carcinogenesis by a 5-lipoxygenase inhibitor, garcinol |
| Q89893266 | Coexistence of Lipid Phases Stabilizes Interstitial Water in the Outer Layer of Mammalian Skin |
| Q41629253 | Combined chemical and electrical enhancement modulates stratum corneum structure |
| Q43811690 | Comparison of experimentally determined and mathematically predicted percutaneous penetration rates of chemicals. |
| Q47878953 | Comparison of four different fuller's earth formulations in skin decontamination. |
| Q33834287 | Comparison of protocols measuring diffusion and partition coefficients in the stratum corneum |
| Q94465669 | Computational Modeling on Aquaporin-3 as Skin Cancer Target: A Virtual Screening Study |
| Q58860055 | ConMedNP: a natural product library from Central African medicinal plants for drug discovery |
| Q92940673 | Controlled Release Film Forming Systems in Drug Delivery: The Potential for Efficient Drug Delivery |
| Q34079560 | Controlled release for local delivery of drugs: barriers and models |
| Q52215934 | Correlation of aqueous and lipid solubilities with flux for prodrugs of 5-fluorouracil, theophylline, and 6-mercaptopurine: A Potts-Guy approach. |
| Q35690247 | Curcumin-loaded colloidal carrier system: formulation optimization, mechanistic insight, ex vivo and in vivo evaluation |
| Q29029457 | Current status and future potential of transdermal drug delivery |
| Q30066516 | Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships. The report and recommendations of ECVAM Workshop 52 |
| Q34328602 | Cyclodextrins in topical drug formulations: theory and practice |
| Q34014392 | Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer |
| Q50073512 | Dendritic polymers for dermal drug delivery. |
| Q44471240 | Dermal absorption of chemicals: estimation by IH SkinPerm |
| Q23924148 | Design and performance of a spreadsheet-based model for estimating bioavailability of chemicals from dermal exposure |
| Q36655012 | Design for optimized topical delivery: Prodrugs and a paradigm change |
| Q44599626 | Determination of Dermal Absorption Qsar/Qsprs by Brute Force Regression: Multiparameter Model Development with Molsuite 2000 |
| Q23913878 | Determination of the effective dermal penetration barrier pH of porcine skin |
| Q23923930 | Determination of the partition coefficients and absorption kinetic parameters of chemicals in a lipophilic membrane/water system by using a membrane-coated fiber technique |
| Q38703265 | Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study |
| Q24169623 | Development of a mixed-effect pharmacokinetic model for vehicle modulated in vitro transdermal flux of topically applied penetrants |
| Q57353630 | Development of cataplasmic transdermal drug delivery system containing eutectic mixture of lidocaine and prilocaine |
| Q37051274 | Diclofenac delays micropore closure following microneedle treatment in human subjects |
| Q52137711 | Diffusion modeling of percutaneous absorption kinetics. 1. Effects of flow rate, receptor sampling rate, and viable epidermal resistance for a constant donor concentration. |
| Q36674276 | Diffusion rates and transport pathways of fluorescein isothiocyanate (FITC)-labeled model compounds through buccal epithelium |
| Q46783238 | Discriminant analysis as a tool to identify compounds with potential as transdermal enhancers |
| Q24169607 | Disposition of Benzyl Alcohol After Topical Application to Human Skin in vitro |
| Q24169611 | Distributed diffusion-clearance model for transient drug distribution within the skin |
| Q52067848 | Does epidermal turnover reduce percutaneous penetration? |
| Q45975229 | Drug delivery to the skin from sub-micron polymeric particle formulations: influence of particle size and polymer hydrophobicity. |
| Q52897836 | Drug release and skin penetration from solid lipid nanoparticles and a base cream: a systematic approach from a comparison of three glucocorticoids. |
| Q34420259 | Drug structure-transport relationships |
| Q39449129 | Dynamics of glycerine and water transport across human skin from binary mixtures |
| Q90377610 | Effect of Metamorphed Keratolytic Agent on the Behavior of Imiquimod Loaded Hybrid Vesicles Containing Gel |
| Q84203747 | Effect of direction (epidermis-to-dermis and dermis-to-epidermis) on the permeation of several chemical compounds through full-thickness skin and stripped skin |
| Q46207737 | Effect of electroporation on transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH) in vitro |
| Q43082308 | Effect of formulation pH on transport of naltrexone species and pore closure in microneedle-enhanced transdermal drug delivery |
| Q42723603 | Effect of ionization and vehicle on skin absorption and penetration of azelaic acid |
| Q32944292 | Effect of stratum corneum heterogeneity, anisotropy, asymmetry and follicular pathway on transdermal penetration |
| Q44693704 | Effects of chronic alcohol consumption on dermal penetration of pesticides in rats |
| Q33631131 | Effects of sizes and conformations of fish-scale collagen peptides on facial skin qualities and transdermal penetration efficiency. |
| Q37589370 | Electroporation as an efficient physical enhancer for skin drug delivery. |
| Q40633999 | Epidermal cell culture model derived from rat keratinocytes with permeability characteristics comparable to human cadaver skin |
| Q47245005 | Epidermal permeability-penetrant structure relationships: 4, QSAR of permeant diffusion across human stratum corneum in terms of molecular weight, H-bonding and electronic charge |
| Q34494194 | Essential oil from Zanthoxylum bungeanum Maxim. and its main components used as transdermal penetration enhancers: a comparative study |
| Q41962550 | Estimation of maximum transdermal flux of nonionized xenobiotics from basic physicochemical determinants |
| Q53409203 | Evaluating Molecular Properties Involved in Transport of Small Molecules in Stratum Corneum: A Quantitative Structure-Activity Relationship for Skin Permeability. |
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| Q42873016 | Evaluation of percutaneous permeation of flurbiprofen and ketoprofen after application of transdermal patches using a lateral sectioning approach in hairless rats |
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| Q53394061 | Fuzzy modeling of skin permeability coefficients. |
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| Q41252565 | Human skin permeation of emerging mycotoxins (beauvericin and enniatins). |
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| Q33820618 | Iontophoresis: electrorepulsion and electroosmosis |
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| Q47730231 | Ligand-based virtual screening, molecular docking, QSAR and pharmacophore analysis of quercetin-associated potential novel analogs against epidermal growth factor receptor. |
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| Q50235417 | Melatonin-based pickering emulsion for skin's photoprotection. |
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| Q43215805 | Methods and measurements for estimating human dermal uptake of volatile organic compounds and for deriving dermal permeability coefficients |
| Q52360839 | Methods of assessing dermal absorption with emphasis on uptake from contaminated vegetation. |
| Q37819486 | Microneedles: a valuable physical enhancer to increase transdermal drug delivery |
| Q24169608 | Mobility of Water in Human Stratum Corneum |
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| Q38386043 | Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest. |
| Q37194304 | Modeling kinetics of subcellular disposition of chemicals. |
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| Q37388525 | Nonlinear quantitative structure-property relationship modeling of skin permeation coefficient. |
| Q23912605 | On the correlation between single-frequency impedance measurements and human skin permeability to water |
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| Q44631882 | Predicting dermal absorption of gas-phase chemicals: transient model development, evaluation, and application |
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| Q23914920 | Predicting skin permeability from complex chemical mixtures |
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| Q23913000 | Predicting skin permeability from complex chemical mixtures: incorporation of an expanded QSAR model |
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| Q36195140 | Prodrugs of theophylline incorporating ethyleneoxy groups in the promoiety: synthesis, characterization, and transdermal delivery |
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| Q47316977 | Quantitative risk assessment for the induction of allergic contact dermatitis: uncertainty factors for mucosal exposures |
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| Q41138072 | Recent developments in topical and transdermal delivery |
| Q38119529 | Reconstructed skin models as emerging tools for drug absorption studies |
| Q23913351 | Regarding the sources of data analyzed with quantitative structure-skin permeability relationship methods (Commentary on 'Investigation of the mechanism of flux across human skin in vitro by quantitative structure-permeability relationships') |
| Q41279377 | Review of theoretical passive drug absorption models: historical background, recent developments and limitations |
| Q36624214 | Review: Takagi-Sugeno fuzzy modeling of skin permeability |
| Q45764525 | Role of partition coefficients in determining the percutaneous penetration of salicylic acid and formaldehyde under varying occlusion durations. |
| Q33684815 | Role of physicochemical properties in the estimation of skin permeability: in vitro data assessment by Partial Least-Squares Regression |
| Q37330047 | Safety assessment and biological effects of a new cold processed SilEmulsion for dermatological purpose |
| Q52575563 | Salt water and skin interactions: new lines of evidence. |
| Q47792526 | Scope and limitation of some approaches to predicting contact hypersensitivity |
| Q23912999 | Selection of appropriate training and validation set chemicals for modelling dermal permeability by U-optimal design |
| Q44947919 | Simple rules defining the potential of compounds for transdermal delivery or toxicity |
| Q91231459 | Skin Permeation Enhancement in Aqueous Solution: Correlation With Equilibrium Enhancer Concentration and Octanol/Water Partition Coefficient |
| Q91271174 | Skin Permeation of Urea Under Finite Dose Condition |
| Q48155216 | Skin delivery of hydrophilic molecules from liposomes and polysaccharide-coated liposomes. |
| Q43215718 | Skin penetration by metal compounds with special reference to copper |
| Q52134133 | Skin penetration of nonsteroidal antiinflammatory drugs out of a lipophilic vehicle: influence of the viable epidermis. |
| Q60948749 | Skin permeation of solutes from metalworking fluids to build prediction models and test a partition theory. |
| Q43478940 | Skin solubility determines maximum transepidermal flux for similar size molecules |
| Q35013492 | Skin structure and mode of action of vesicles |
| Q34341281 | Skin, the final frontier |
| Q46471986 | Solution equilibria and the X-ray structure of Cu(ii) complexation with 3-amino-N-(pyridin-2-ylmethyl)propanamide, a pseudo-mimic of human serum albumin |
| Q52069729 | Solvation enthalpies as descriptors of structure--in vitro percutaneous permeation relationship of benzoxazinones regioisomers. |
| Q45228819 | Structural insights of JAK2 inhibitors: pharmacophore modeling and ligand-based 3D-QSAR studies of pyrido-indole derivatives |
| Q42876136 | Structure Enhancement Relationship of Chemical Penetration Enhancers in Drug Transport across the Stratum Corneum. |
| Q33919858 | Structure-skin permeability relationship of dendrimers |
| Q53401303 | Structure-toxicity relationships of polycyclic aromatic hydrocarbons using molecular quantum similarity. |
| Q45088870 | Sunscreens containing physical UV blockers can increase transdermal absorption of pesticides |
| Q89909590 | Surging footprints of mathematical modeling for prediction of transdermal permeability |
| Q42318665 | SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules |
| Q71562503 | Synergistic effects of chemical enhancers and therapeutic ultrasound on transdermal drug delivery |
| Q61450879 | Synthesis of diN-Substituted Glycyl-Phenylalanine Derivatives by Using Ugi Four Component Reaction and Their Potential as Acetylcholinesterase Inhibitors |
| Q38450152 | TOPS-MODE versus DRAGON descriptors to predict permeability coefficients through low-density polyethylene |
| Q44941810 | Targeted dermal delivery of highly potent anti-varicella zoster virus nucleoside analogues from saturated solutions and ethanolic oil-in-water creams |
| Q56483690 | The Factors that Influence Skin Penetration of Solutes* |
| Q42037691 | The Flux of Phenolic Compounds through Silicone Membranes. |
| Q45911432 | The OSIRIS Weight of Evidence approach: ITS for skin sensitisation. |
| Q46595751 | The application and limitations of mathematical modelling in the prediction of permeability across mammalian skin and polydimethylsiloxane membranes |
| Q39952786 | The application of Gaussian processes in the prediction of percutaneous absorption |
| Q38382133 | The application of machine learning to the modelling of percutaneous absorption: an overview and guide |
| Q40530325 | The chemistry of contact allergy: why is a molecule allergenic? |
| Q51596074 | The computation of lipophilicities of ⁶⁴Cu PET systems based on a novel approach for fluctuating charges. |
| Q51413560 | The dermal delivery of lignocaine: influence of ion pairing. |
| Q48155200 | The effect of additives on release and in vitro skin retention of flavonoids from emulsion and gel semisolid formulations. |
| Q31043697 | The effect of bilayer and hexagonal H(II) phase lipid films on transepidermal water loss |
| Q44470103 | The effect of lipid and aqueous solubilities on flux of nicotinic acid esters from water through silicone membrane |
| Q43861612 | The effect of the nature of H-bonding groups on diffusion through PDMS membranes saturated with octanol and toluene. |
| Q41995825 | The effects of equine skin preparation on transdermal drug penetration in vitro. |
| Q43225705 | The potential dermal irritating effect of residual (meth)acrylic monomers in pressure sensitive adhesive tapes |
| Q30315979 | The potential of anti-malarial compounds derived from African medicinal plants, part III: an in silico evaluation of drug metabolism and pharmacokinetics profiling |
| Q38648533 | The potential of polymeric film-forming systems as sustained delivery platforms for topical drugs |
| Q46110282 | The role of corneocytes in skin transport revised--a combined computational and experimental approach |
| Q44373508 | The role of stratum corneum and dermal microvascular perfusion in penetration and tissue levels of water-soluble drugs investigated by microdialysis |
| Q73088712 | The selection of non-steroidal anti-inflammatory agents for dermal delivery |
| Q44279187 | The usual suspects-influence of physicochemical properties on lag time, skin deposition, and percutaneous penetration of nine model compounds. |
| Q88945863 | Theoretical investigations into the intermolecular hydrogen-bonding interactions of N-(hydroxymethyl)acetamide dimers |
| Q47349691 | Time-Resolved Infrared ATR Measurements of Liposome Transport Kinetics in Human Keratinocyte Cultures and Skin Reveals a Dependence on Liposome Size and Phase State |
| Q53274831 | Tissue distribution and dermal drug determination of indomethacin transdermal-absorption patches. |
| Q34470800 | Topical application of drugs: mechanisms involved in chemical enhancement |
| Q43568245 | Topical delivery of 5-fluorouracil (5-Fu) by 3-alkylcarbonyl-5-Fu prodrugs |
| Q44435890 | Topical delivery of 5-fluorouracil and 6-mercaptopurine by their alkylcarbonyloxymethyl prodrugs from water: vehicle effects on design of prodrugs |
| Q46850063 | Topical non-peptide antagonists of sensory neurotransmitters substance P and CGRP do not modify patch test and prick test reactions: a vehicle-controlled, double-blind pilot study. |
| Q37871068 | Topically applied KTTKS: a review |
| Q35549914 | Towards a quantitative theory of epidermal calcium profile formation in unwounded skin |
| Q35127630 | Toxic Effects of Chemical Mixtures |
| Q35124677 | Transdermal Drug Delivery of Insulin with Ultradeformable Carriers |
| Q46579883 | Transdermal delivery enhancement of haloperidol from gel formulations by 1,8-cineole |
| Q24655598 | Transdermal delivery of bupropion and its active metabolite, hydroxybupropion: a prodrug strategy as an alternative approach |
| Q43508310 | Transdermal delivery of levosimendan |
| Q36329463 | Transdermal drug delivery: basic principles for the veterinarian |
| Q74341807 | Transdermal drug delivery: overcoming the skin's barrier function |
| Q41120856 | Transdermal drug delivery: useful paradigms |
| Q34599711 | Transport of proteins dissolved in organic solvents across biomimetic membranes |
| Q53776953 | Two steps modification for improvement of cyclobenzaprine transdermal delivery: releasing from patch and penetrating through skin. |
| Q28213194 | Ultradeformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements |
| Q54147516 | Ultraflexible vesicles, Transfersomes, have an extremely low pore penetration resistance and transport therapeutic amounts of insulin across the intact mammalian skin. |
| Q71854922 | Uptake of Chloroform by Skin During Short Exposures to Contaminated Water |
| Q24815781 | Use of QSARs in international decision-making frameworks to predict health effects of chemical substances |
| Q37117105 | Use of transdermal drug formulations in the elderly |
| Q52009009 | Using Argumentation for Absolute Reasoning about the Potential Toxicity of Chemicals |
| Q46990112 | Variation in barrier impairment and inflammation of human skin as determined by sodium lauryl sulphate penetration rate |
| Q51686080 | Vehicle composition influence on the microneedle-enhanced transdermal flux of naltrexone hydrochloride. |
| Q30777010 | Visualization of the lipid barrier and measurement of lipid pathlength in human stratum corneum |
| Q39694956 | What determines skin sensitization potency: Myths, maybes and realities. The 500 molecular weight cut-off: An updated analysis |
| Q51394463 | pH, pK(a) and dermal delivery. |
| Q30479595 | pH-dependent permeation of amino acids through isolated ivy cuticles is affected by cuticular water sorption and hydration shell size of the solute |
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