Utilization of Model Compounds to Evaluate Effects of Slight Chemical Modifications on Their Distribution Pharmacokinetic Parameters in Rats and Mechanisms Inferred for Their Transmembrane Transport

scientific article (publication date: November 1975)

Utilization of Model Compounds to Evaluate Effects of Slight Chemical Modifications on Their Distribution Pharmacokinetic Parameters in Rats and Mechanisms Inferred for Their Transmembrane Transport is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JPS.2600641112
P8608Fatcat IDrelease_qotq245cxfainhfjix3p4vor5i
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S002235491540512X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S002235491540512X?httpAccept=text/plain
P698PubMed publication ID1195111

P2093author name stringY. M. Amin
J. B. Nagwekar
P2860cites workJournal of Chemical PhysicsQ900472
Pharmacological ReviewsQ2085079
Mechanistic Evaluation of Modifications of Distribution Pharmacokinetic Parameters of Model Organic Anions in Presence of a Model Renal Tubular Secretion Inhibitor in RatsQ28340703
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Kinetics of Urinary Excretion of D-(−)-Mandelic Acid and its Homologs II: Competitive Inhibitory Effect of D-(−)-Mandelic Acid and Dl-Tropic Acid on Their Renal Tubular Secretion in RatsQ39383134
Pharmacokinetics Molecular Modification: Implications in Drug Design EvaluationQ39927738
Patterns of nonelectrolyte permeability in human red blood cell membraneQ41920826
Michaelis–Menten Kinetics of Renal Tubular Secretion of D-(−)-p-Methyl Mandelic Acid and D-(−)-p-Ethyl Mandelic Acid in RatsQ42239254
The cerebrospinal fluid valves.Q51307242
Influence of temperature and nature of hydrophobic groups on thermodynamic parameters of hydrophobic bonding in a model polymeric system and their implications in drug-biopolymer interactions.Q52935950
COMPT, a time-sharing program for nonlinear regression analysis of compartmental models of drug distributionQ68519310
Michaelis—menten Kinetic Parameters of Renal Tubular Secretion of para-alkylated Mandelic Acids and Their Use in Revealing Possible Chemical Characteristics around Receptor Site of Secretion Carrier in RatsQ69543000
Kinetics of three structurally related bicyclic antidepressant compounds--a comparison in the dogQ70044248
Pharmacokinetics of three sulfonamides in the rabbitQ70339772
Pharmacokinetics, metabolism, and urinary excretion of [3H]-alphaprodine in dogsQ70418925
Utilization of a Model Copolymer to Evaluate the Contribution of Hydrophobic Bonding in Drug BindingQ71442862
Kinetics of Urinary Excretion of D-(−)-Mandelic Acid and its Homologs I: Mutual Inhibitory Effect of D-(−)-Mandelic Acid and its Certain Homologs on Their Renal Tubular Secretion in RatsQ71442882
Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeabilityQ75878007
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
pharmaceutical scienceQ7180763
transmembrane proteinQ424204
transmembrane transportQ14820680
P304page(s)1804-12
P577publication date1975-11-01
P1433published inJournal of Pharmaceutical SciencesQ3186933
P1476titleUtilization of model compounds to evaluate effects of slight chemical modifications on their distribution. Pharmacokinetic parameters in rats and mechanisms inferred for their transmembrane transport
Utilization of Model Compounds to Evaluate Effects of Slight Chemical Modifications on Their Distribution Pharmacokinetic Parameters in Rats and Mechanisms Inferred for Their Transmembrane Transport
P478volume64

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cites work (P2860)
Q34694247A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent.
Q28340703Mechanistic Evaluation of Modifications of Distribution Pharmacokinetic Parameters of Model Organic Anions in Presence of a Model Renal Tubular Secretion Inhibitor in Rats
Q39290709Pharmacokinetic Evidence for Possible Renal Accumulation of Model Organic Anions in Rats
Q57803380Photogenerated Radical in Phenylglyoxylic Acid for in Vivo Hyperpolarized C MR with Photosensitive Metabolic Substrates

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