Chemoprophylaxis of influenza A virus infections, with single doses of zanamivir, demonstrates that zanamivir is cleared slowly from the respiratory tract

scientific article

Chemoprophylaxis of influenza A virus infections, with single doses of zanamivir, demonstrates that zanamivir is cleared slowly from the respiratory tract is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/AAC.43.11.2642
P932PMC publication ID89537
P698PubMed publication ID10543741

P2093author name stringT Wong
S Parry
L Crossman
P J Morley
I J Owens
R J Fenton
D Gower
P2860cites workInfluenza vaccines. A reappraisal of their use.Q41676828
Human influenza A H5N1 virus related to a highly pathogenic avian influenza virusQ43209132
Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteersQ44779710
Efficacy of zanamivir for chemoprophylaxis of nursing home influenza outbreaks.Q45114160
A controlled trial of amantadine and rimantadine in the prophylaxis of influenza A infectionQ45148150
Amantadine resistance in clinical influenza A (H3N2) and (H1N1) virus isolatesQ45829317
Evaluation of amantadine in artificially induced A2 and B influenzaQ47770553
Field investigation of influenza vaccine effectiveness on morbidity.Q50873540
The Roles of Vaccination and Amantadine Prophylaxis in Controlling an Outbreak of Influenza A (H3N2) in a Nursing HomeQ57112977
Efficacy and safety of low dosage amantadine hydrochloride as prophylaxis for influenza AQ69595599
Randomised trial of efficacy and safety of inhaled zanamivir in treatment of influenza A and B virus infections. The MIST (Management of Influenza in the Southern Hemisphere Trialists) Study GroupQ77719323
Amantadine and ribavirin aerosol treatment of influenza A and B infection in miceQ28367135
Inhibition of influenza virus replication in mice by GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is consistent with extracellular activity of viral neuraminidase (sialidase)Q28368367
4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitroQ28378588
Rational design of potent sialidase-based inhibitors of influenza virus replicationQ29616647
Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in miceQ30431958
Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokineticsQ30451349
Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infectionsQ30462342
Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenzaQ30467966
Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections. GG167 Influenza Study Group.Q30471016
GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is a potent inhibitor of influenza virus in ferretsQ35120465
Protective efficacy of low-dose amantadine in adults challenged with wild-type influenza A virusQ35542114
Implications of viral resistance to amantadine in control of influenza AQ35811011
Immunity to influenza in ferrets. I. Response to live and killed virusQ36130219
Genetic basis of resistance to rimantadine emerging during treatment of influenza virus infectionQ36866575
Prophylaxis and treatment of influenzaQ38139920
Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071.Q39557208
Zanamivir in the prevention of influenza among healthy adults: a randomized controlled trialQ40636281
Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitorQ41042625
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectinfluenza A virusQ834390
zanamivirQ146075
P304page(s)2642-2647
P577publication date1999-11-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleChemoprophylaxis of influenza A virus infections, with single doses of zanamivir, demonstrates that zanamivir is cleared slowly from the respiratory tract
P478volume43

Reverse relations

cites work (P2860)
Q34083704In vitro and in vivo assay systems for study of influenza virus inhibitors
Q30404200Long-term respiratory follow-up of H1N1 infection
Q40424441Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen
Q24798602Progress toward generating a ferret model of cystic fibrosis by somatic cell nuclear transfer
Q44420217Semi-quantitative detection of viral RNA in influenza A virus-infected mice for evaluation of antiviral compounds
Q35976713Viral diseases of ferrets
Q34492611Zanamivir: an update of its use in influenza