A second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain

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A second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain is …
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scholarly articleQ13442814

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P356DOI10.1017/S1355838201000243
P932PMC publication ID1370151
P698PubMed publication ID11453071
P5875ResearchGate publication ID11888848

P2093author name stringJ Ofengand
M Del Campo
N S Gutgsell
S Raychaudhuri
P2860cites workA pseudouridine synthase required for the formation of two universally conserved pseudouridines in ribosomal RNA is essential for normal growth of Escherichia coliQ41983956
A conserved aspartate of tRNA pseudouridine synthase is essential for activity and a probable nucleophilic catalystQ46211142
Mapping the position of translational elongation factor EF-G in the ribosome by directed hydroxyl radical probingQ46303425
Mapping the inside of the ribosome with an RNA helical rulerQ46682838
Critical aspartic acid residues in pseudouridine synthasesQ47942240
The involvement of two distinct regions of 23 S ribosomal RNA in tRNA selection.Q54598388
Clustering of pseudouridine residues around the peptidyltransferase center of yeast cytoplasmic and mitochondrial ribosomes.Q54623940
Four newly located pseudouridylate residues in Escherichia coli 23S ribosomal RNA are all at the peptidyltransferase center: analysis by the application of a new sequencing technique.Q54651150
Identification of intermolecular RNA cross-links at the subunit interface of the Escherichia coli ribosomeQ54681970
Functional requirement of a site-specific ribose methylation in ribosomal RNAQ72669426
Translational defects of Escherichia coli mutants deficient in the Um(2552) 23S ribosomal RNA methyltransferase RrmJ/FTSJQ73800291
Mapping of pseudouridine residues in RNA to nucleotide resolutionQ77404759
Nucleotides in 23S rRNA protected by the association of 30S and 50S ribosomal subunitsQ77760336
X-ray crystal structures of 70S ribosome functional complexesQ27619733
The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase IQ27620912
Structure of Hsp15 reveals a novel RNA-binding motifQ27621387
The complete atomic structure of the large ribosomal subunit at 2.4 A resolutionQ27626400
RNA methylation under heat shock controlQ27626992
Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi(2819) in 21S mitochondrial ribosomal RNA.Q27931987
Pseudouridine synthases: four families of enzymes containing a putative uridine-binding motif also conserved in dUTPases and dCTP deaminasesQ27939204
Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?Q32075110
16S ribosomal RNA pseudouridine synthase RsuA of Escherichia coli: deletion, mutation of the conserved Asp102 residue, and sequence comparison among all other pseudouridine synthasesQ33865623
Functional effect of deletion and mutation of the Escherichia coli ribosomal RNA and tRNA pseudouridine synthase RluA.Q33866206
The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23 S ribosomal RNA methyltransferaseQ33896727
Deletion of the Escherichia coli pseudouridine synthase gene truB blocks formation of pseudouridine 55 in tRNA in vivo, does not affect exponential growth, but confers a strong selective disadvantage in competition with wild-type cellsQ34363266
The mechanism of pseudouridine synthase I as deduced from its interaction with 5-fluorouracil-tRNA.Q36742177
The gene for a tRNA modifying enzyme, m5U54-methyltransferase, is essential for viability in Escherichia coliQ37599653
A new heat shock protein that binds nucleic acidsQ38330093
Hsp15: a ribosome-associated heat shock proteinQ40387128
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)990-998
P577publication date2001-07-01
P1433published inRNAQ7277164
P1476titleA second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain
P478volume7

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cites work (P2860)
Q24540093A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA
Q33397658A pseudouridine synthase homologue is critical to cellular differentiation in Toxoplasma gondii
Q41355883A snoRNA that guides the two most conserved pseudouridine modifications within rRNA confers a growth advantage in yeast.
Q27641144Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification Enzyme
Q34108217Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli
Q34306791Crystal structure of the apo forms of psi 55 tRNA pseudouridine synthase from Mycobacterium tuberculosis: a hinge at the base of the catalytic cleft
Q27642972Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli
Q40430547Cytosines do it, thymines do it, even pseudouridines do it--base flipping by an enzyme that acts on RNA.
Q37033455Genetic interactions of smc, ftsK, and parB genes in Streptomyces coelicolor and their developmental genome segregation phenotypes
Q28364834Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli
Q41892615Identification of genes potentially involved in solute stress response in Sphingomonas wittichii RW1 by transposon mutant recovery
Q36575138Identification of novel virulence-associated genes via genome analysis of hypothetical genes
Q33292929Identifying modifications in RNA by MALDI mass spectrometry
Q33188085Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry
Q34484867Inactivation of the RluD pseudouridine synthase has minimal effects on growth and ribosome function in wild-type Escherichia coli and Salmonella enterica
Q30363162Insights into the biology of Escherichia coli through structural proteomics.
Q44023081Lack of pseudouridine 38/39 in the anticodon arm of yeast cytoplasmic tRNA decreases in vivo recoding efficiency
Q24536220MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase
Q34124804Methylation at nucleotide G745 or G748 in 23S rRNA distinguishes Gram-negative from Gram-positive bacteria
Q34351361Methylation of 23S rRNA nucleotide G745 is a secondary function of the RlmAI methyltransferase
Q54599572Modifications in Thermus thermophilus 23 S ribosomal RNA are centered in regions of RNA-RNA contact.
Q46503233Mutations in SUPPRESSOR OF VARIEGATION1, a factor required for normal chloroplast translation, suppress var2-mediated leaf variegation in Arabidopsis
Q47548659Positive-sense RNA viruses reveal the complexity and dynamics of the cellular and viral epitranscriptomes during infection.
Q35133639Pseudouridines and pseudouridine synthases of the ribosome.
Q34717123Pseudouridylation of helix 69 of 23S rRNA is necessary for an effective translation termination
Q41865855Random pseuoduridylation in vivo reveals critical region of Escherichia coli 23S rRNA for ribosome assembly
Q34502544Recognition of a complex substrate by the KsgA/Dim1 family of enzymes has been conserved throughout evolution
Q34571025Ribosomal RNA pseudouridines and pseudouridine synthases
Q24632475RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA
Q27642371Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit
Q34618761The Aspergillus nidulans swoC1 Mutant Shows Defects in Growth and Development
Q42010185The pseudouridine synthase RluD is required for normal ribosome assembly and function in Escherichia coli
Q31106770Thermus thermophilus L11 methyltransferase, PrmA, is dispensable for growth and preferentially modifies free ribosomal protein L11 prior to ribosome assembly
Q34816382YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.
Q28610126rRNA modifications and ribosome function

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