In vitro resistance profile of the human immunodeficiency virus type 1 protease inhibitor BMS-232632

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In vitro resistance profile of the human immunodeficiency virus type 1 protease inhibitor BMS-232632 is …
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scholarly articleQ13442814

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P356DOI10.1128/AAC.44.9.2319-2326.2000
P8608Fatcat IDrelease_tzdtdfqugfelvjeolqbg4m4m3e
P3181OpenCitations bibliographic resource ID2251652
P932PMC publication ID90064
P698PubMed publication ID10952574

P2093author name stringD Stock
Y F Gong
R J Colonno
P F Lin
B S Robinson
R E Rose
C Deminie
T P Spicer
P2860cites workABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humansQ27729982
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In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl proteaseQ28367941
Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitorQ28368263
In vitro selection and characterization of human immunodeficiency virus type 1 variants with increased resistance to ABT-378, a novel protease inhibitorQ28368369
Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitorQ28368832
Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir.Q28369030
L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitorQ28369664
Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitorsQ28378853
Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitorsQ28378860
Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sitesQ28379086
Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus proteaseQ28379166
Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitorQ28379356
A mutation in human immunodeficiency virus type 1 protease at position 88, located outside the active site, confers resistance to the hydroxyethylurea inhibitor SC-55389AQ28379487
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitorsQ29620622
Treatment with amprenavir alone or amprenavir with zidovudine and lamivudine in adults with human immunodeficiency virus infection. AIDS Clinical Trials Group 347 Study Team.Q33539266
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Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir) monotherapyQ33784635
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Resistance to human immunodeficiency virus type 1 protease inhibitors.Q39559316
Resistance-associated loss of viral fitness in human immunodeficiency virus type 1: phenotypic analysis of protease and gag coevolution in protease inhibitor-treated patientsQ39580564
Novel Gag-Pol frameshift site in human immunodeficiency virus type 1 variants resistant to protease inhibitorsQ39582620
Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitorsQ39780160
The retroviral enzymesQ40394916
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Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959.Q41381139
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Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapyQ42282495
Ordered accumulation of mutations in HIV protease confers resistance to ritonavirQ42555782
The effect of high-dose saquinavir on viral load and CD4+ T-cell counts in HIV-infected patients.Q42630241
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New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activityQ45033160
A preliminary evaluation of nelfinavir mesylate, an inhibitor of human immunodeficiency virus (HIV)-1 protease, to treat HIV infectionQ45755838
In vivo resistance to a human immunodeficiency virus type 1 proteinase inhibitor: mutations, kinetics, and frequenciesQ45770453
Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538).Q48061498
Recent developments in HIV protease inhibitor therapyQ77354774
HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapyQ77386253
Antiretroviral therapies in HIV-1 infectionQ94447136
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)2319-26
P577publication date2000-09-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleIn vitro resistance profile of the human immunodeficiency virus type 1 protease inhibitor BMS-232632
P478volume44