Cystatin, a protein inhibitor of cysteine proteinases. Improved purification from egg white, characterization, and detection in chicken serum

scientific article

Cystatin, a protein inhibitor of cysteine proteinases. Improved purification from egg white, characterization, and detection in chicken serum is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ2110129
P932PMC publication ID1154336
P698PubMed publication ID6409085
P5875ResearchGate publication ID16787387

P2093author name stringM J Nicklin
D C Sunter
A J Barrett
M A Brown
A Anastasi
A A Kembhavi
C A Sayers
P2860cites workL-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and LQ24531160
Tissue sulfhydryl groupsQ26778486
Immunochemical quantitation of antigens by single radial immunodiffusionQ28248574
Cathepsin B, Cathepsin H, and cathepsin LQ28277583
The determination of enzyme inhibitor constantsQ29618526
Protein inhibitors of proteinasesQ29619496
New observations on the substrate specificity of cathepsin C (dipeptidyl aminopeptidase I). Including the degradation of beta-corticotropin and other peptide hormonesQ34206202
Isolation and characterization of papaya peptidase A from commercial chymopapainQ34371363
A reporter group delivery system with both absolute and selective specificity for thiol groups and an improved fluorescent probe containing the 7-nitrobenzo-2-oxa-1,3-diazole moietyQ39080240
Purification and Properties of Two Protease Inhibitors from Rat Skin Inhibiting Papain and Other SH-ProteasesQ39134358
The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin moleculeQ39571590
Lysosomal Cysteine ProteinasesQ41204117
A necessary modification to the preparation of papain from any high-quality latex of Carica papaya and evidence for the structural integrity of the enzyme produced by traditional methodsQ41543135
The amino acid sequence of γ-crystallin (fraction II) from calf lensQ41762387
Human cathepsin HQ41918367
A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitorsQ42924868
Purification and some characteristics of the human epidermal SH-protease inhibitorQ44755420
Observations on Molecular Weight Determinations on Polyacrylamide GelQ47393994
Some properties of a ficin-papain inhibitor from avion egg whiteQ47920229
An undescribed trypsin inhibitor in egg white.Q64945955
Chicken alpha2-proteinase inhibitor: a serum protein homologous with ovoinhibitor of egg whiteQ68351851
Inhibitory mechanism of sericystatin, an intracellular proteinase inhibitor, reacting with cysteine proteinasesQ70196813
Endogenous thiol protease inhibitor from rat liverQ70786608
Chemical Fixation of Enzymes to Cyanogen Halide Activated Polysaccharide CarriersQ71756089
Ficin and papain inhibitor from chicken egg whiteQ72044085
Separation of dansyl-amino acids by polyamide layer chromatographyQ72232081
Latent collagenase from human polymorphonuclear leucocytes and activation to collagenase by removal of an inhibitorQ72868402
Purification of the two major forms of rat pituitary corticotropin using only reversed-phase liquid chromatographyQ72910933
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)129-38
P577publication date1983-04-01
P1433published inBiochemical JournalQ864221
P1476titleCystatin, a protein inhibitor of cysteine proteinases. Improved purification from egg white, characterization, and detection in chicken serum
P478volume211

Reverse relations

cites work (P2860)
Q28361171A catalytically active high-Mr form of human cathepsin B from sputum
Q73635017A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi
Q42856825A cystatin-like cysteine proteinase inhibitor from venom of the African puff adder (Bitis arietans).
Q39051585A filarial cysteine protease inhibitor down-regulates T cell proliferation and enhances interleukin-10 production
Q28564616A rapid two-step purification of rat cystatin C, one major inhibitor of cysteine proteinases
Q33908903A virus essential for insect host-parasite interactions encodes cystatins.
Q34430599Affinity purification of the novel cysteine proteinase papaya proteinase IV, and papain from papaya latex
Q34181739Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C)
Q46498368Antigenic properties of cystatin-binding cysteine proteinases from Neodiplostomum seoulense
Q47552647Antioxidant, angiotensin-converting enzyme inhibitory activity and other functional properties of egg white proteins and their derived peptides - A review
Q30821768Atlantic salmon (Salmo salar L.) skin contains a novel kininogen and another cysteine proteinase inhibitor
Q45342885Binding of glycated ovocystatin to rat renal brush border membranes.
Q41815677Calorimetric measurements of thermal denaturation of stefins A and B. Comparison to predicted thermodynamics of stefin-B unfolding
Q39935408Candida albicans produces a cystatin-type cysteine proteinase inhibitor
Q47303692Canine plasma kininogen: evidence for the presence of two kininogens and purification of high molecular weight kininogen and characterization as multi-functional molecule
Q37435051Cathepsin L and cystatin B gene expression discriminates immune coelomic cells in the leech Theromyzon tessulatum
Q43685349Changes in chicken egg white cystatin concentration and isoforms during embryogenesis
Q53848923Characterisation of a cysteine protease from bloodstream forms of Trypanosoma congolense.
Q42161502Characterization by rapid-kinetic and equilibrium methods of the interaction between N-terminally truncated forms of chicken cystatin and the cysteine proteinases papain and actinidin
Q28551898Characterization of a Recombinant Cathepsin B-Like Cysteine Peptidase from Diaphorina citri Kuwayama (Hemiptera: Liviidae): A Putative Target for Control of Citrus Huanglongbing
Q42847423Characterization of the interface structure of enzyme-inhibitor complex by using hydrogen-deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
Q34484586Chelidocystatin, a novel phytocystatin from Chelidonium majus
Q24531214Cloning and expression of mouse legumain, a lysosomal endopeptidase
Q24336534Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase
Q74611956Comparison of three liquid chromatographic methods for egg-white protein analysis
Q42463912Cystatin C is highly expressed in the human male reproductive system
Q37002169Cystatin E/M Suppresses Tumor Cell Growth through Cytoplasmic Retention of NF-κB.
Q28362928Cystatin capture enzyme-linked immunosorbent assay for serodiagnosis of human clonorchiasis and profile of captured antigenic protein of Clonorchis sinensis
Q44740563Cystatin forms a tetramer through structural rearrangement of domain-swapped dimers prior to amyloidogenesis
Q41868134Cystatin-like cysteine proteinase inhibitors from human liver
Q41883524Cystatin. Amino acid sequence and possible secondary structure
Q69043076Cystatins from bovine brain: purification, some properties, and action on substance P degrading activity
Q34105072Cystatins in human tear fluid
Q44024607Cystatins of filarial nematodes up-regulate the nitric oxide production of interferon-gamma-activated murine macrophages
Q35361416Cystatins--inhibitors of cysteine proteinases
Q46800567Cysteine protease and its inhibitor in experimentally produced squamous cell carcinomas in hairless mouse skin
Q69737440Degradation of laminin by human tumor cathepsin B
Q41820346Differential changes in the association and dissociation rate constants for binding of cystatins to target proteinases occurring on N-terminal truncation of the inhibitors indicate that the interaction mechanism varies with different enzymes
Q33640459Effect of contact lenses on the protein composition in tear film: a ProteinChip study
Q47330486Effect of serine protease inhibitor from squid ovary on gel properties of surimi from Indian mackerel.
Q36848432Egg white proteins
Q42425115Enzymatic characterization of germination-specific cysteine protease-1 expressed transiently in cotyledons during the early phase of germination
Q42048203Escherichia coli dihydrodipicolinate synthase. Identification of the active site and crystallization
Q41828555Evidence by chemical modification that tryptophan-104 of the cysteine-proteinase inhibitor chicken cystatin is located in or near the proteinase-binding site
Q86624448Factors affecting the binding between fusicoccin and plasma membranes from maize roots
Q42745469Functional expression of recombinant human stefin A in mammalian and bacterial cells
Q72067837Genetic polymorphisms of the CST2 locus coding for cystatin SA
Q38597454Genetics of human salivary proteins
Q44597635Global proteome changes in larvae of Callosobruchus maculatus Coleoptera:Chrysomelidae:Bruchinae) following ingestion of a cysteine proteinase inhibitor.
Q41874926Glutathione S-transferase can be used as a C-terminal, enzymatically active dimerization module for a recombinant protease inhibitor, and functionally secreted into the periplasm of Escherichia coli
Q38297464Hairpin loop mutations of chicken cystatin have different effects on the inhibition of cathepsin B, cathepsin L and papain
Q41966572Hereditary cystatin C amyloid angiopathy: monitoring the presence of the Leu-68-->Gln cystatin C variant in cerebrospinal fluids and monocyte cultures by MS.
Q34257291Human cystatin, a new protein inhibitor of cysteine proteinases
Q42852932Human low-Mr kininogen contains three copies of a cystatin sequence that are divergent in structure and in inhibitory activity for cysteine proteinases
Q41840247Human plasma alpha-cysteine proteinase inhibitor. Purification by affinity chromatography, characterization and isolation of an active fragment
Q24529583Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry
Q41785785Human sputum cathepsin B degrades proteoglycan, is inhibited by α2-macroglobulin and is modulated by neutrophil elastase cleavage of cathepsin B precursor and cystatin C
Q38362165Hybrids of chicken cystatin with human kininogen domain 2 sequences exhibit novel inhibition of calpain, improved inhibition of actinidin and impaired inhibition of papain, cathepsin L and cathepsin B.
Q41838678Identification of monomeric alpha-macroglobulin proteinase inhibitors in birds, reptiles, amphibians and mammals, and purification and characterization of a monomeric alpha-macroglobulin proteinase inhibitor from the American bullfrog Rana catesbeia
Q41639259In Vitro Antibacterial Activity of Cysteine Protease Inhibitor from Kiwifruit (Actinidia deliciosa).
Q37790560In search of decoy/guardee to R genes: deciphering the role of sugars in defense against Fusarium wilt in chickpea
Q50495950In vitro and in vivo antifungal properties of cysteine proteinase inhibitor from green kiwifruit.
Q50935254Influence of aminoglycoside antibiotics on chicken cystatin binding to renal brush-border membranes.
Q42673765Inhibition of chicken calpain II by proteins of the cystatin superfamily and alpha 2-macroglobulin
Q42848203Inhibition of cysteine proteinases and dipeptidyl peptidase I by egg-white cystatin
Q68921539Inhibition of cysteine proteinases by a protein inhibitor from potato
Q70547216Interaction between cystatin-derived peptides and papain
Q41878875Interaction of chicken cystatin with inactivated papains
Q24527331Interaction of recombinant human cystatin C with the cysteine proteinases papain and actinidin
Q39951107Internalization of cystatin C in human cell lines
Q42709692Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors
Q49885401Involvement of Cystatin C in Immunity and Apoptosis.
Q71621320Isolation and amino acid sequence of a cystatin-type cysteine proteinase inhibitor from bovine hoof
Q43699272Isolation of Nine Human Plasma Proteinase Inhibitors by Sequential Affinity Chromatography
Q72765495Isolation of cysteine proteinase inhibitor, cystatin A, from human nails
Q38557771Journey of cystatins from being mere thiol protease inhibitors to at heart of many pathological conditions
Q42794953Kinetics of inhibition of platelet calpain II by human kininogens
Q24811240Late stage inhibition of hematogenous melanoma metastasis by cystatin C over-expression
Q47748493Membrane lipid oxidation and proteolytic activity in thigh muscles from broilers fed different diets.
Q44931732Modification of sheep plasma kininogen by free radicals
Q45025400Molecular cloning, expression, and functional characterization of a cystatin from pineapple stem
Q43726243Molecular cloning, genomic structure, and tissue distribution of EW135, a novel chicken egg white protein with group B scavenger receptor cysteine-rich domains
Q41833360Papain labelled with fluorescent thiol-specific reagents as a probe for characterization of interactions between cysteine proteinases and their protein inhibitors by competitive titrations
Q72659613Pig leukocyte cysteine proteinase inhibitor (PLCPI), a new member of the stefin family
Q73996168PinA inhibits ATP hydrolysis and energy-dependent protein degradation by Lon protease
Q44720795Potential utility of various protease inhibitors for improving the intestinal absorption of insulin in rats
Q42160688Probing the functional role of the N-terminal region of cystatins by equilibrium and kinetic studies of the binding of Gly-11 variants of recombinant human cystatin C to target proteinases
Q46132641Production of a His-tagged canecystatin in transgenic sugarcane and subsequent purification.
Q54627972Production, inhibitory activity, folding and conformational analysis of an N-terminal and an internal deletion variant of chicken cystatin.
Q45942638Prolyl endopeptidase purified from granulomatous inflammation in mice.
Q28202088Protein inhibitors form complexes with procathepsin L and augment cleavage of the propeptide
Q36836252Protein inhibitors of proteinases from brain
Q39831060Proteinases in inflammatory demyelinating disease
Q47749081Proteolysis and tenderisation in reindeer (Rangifer tarandus tarandus L.) bull longissimus thoracis muscle of varying ultimate pH.
Q44765382Purification and characterization of a chicken egg white cystatin variant expressed in an Escherichia coli pIN-III-ompA system
Q67472024Purification and characterization of a cystatin-type cysteine proteinase inhibitor in the human hair shaft
Q42159289Purification and characterization of a new cystatin inhibitor from Taiwan cobra (Naja naja atra) venom
Q41093399Purification and characterization of an alpha-macroglobulin proteinase inhibitor from the mollusc Octopus vulgaris
Q46286189Purification and characterization of cathepsin B-like cysteine protease from cotyledons of daikon radish, Raphanus sativus
Q48388158Purification and characterization of high molecular mass and low molecular mass cystatin from goat brain
Q42283892Purification and characterization of thaumatopain, a cysteine protease from the arils of the plant Thaumatococcus daniellii
Q47185476Purification and characterization of α1-thiol proteinase inhibitor and its identity with kinin- and fragment 1·2-free high molecular weight kininogen
Q45297051Purification and determination of inhibitory activity of recombinant soyacystatin for surimi application
Q44608510Purification and properties of cysteine proteinase inhibitors from rabbit skeletal muscle
Q70309096Purification of two species of exudate cysteine-proteinase inhibitors that are acute-phase reactants in the carrageenin-induced inflammation in rats
Q28505331Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme
Q42662817Quail cystatin: isolation and characterisation of a new member of the cystatin family and its hypothetical interaction with cathepsin B.
Q48150578Recombinant chicken egg white cystatin variants of the QLVSG region
Q74590951Refolding of recombinant sulphonated procathepsin S and of reduced chicken cystatin; implications for renaturation experiments
Q44695448Regulation of cathepsin B and L expression in vitro in gastric cancer tissues by egg cystatin
Q36429583Role of cystatins in tumor neovascularization
Q72077110Structural dissection of the multidomain kininogens. Fine mapping of the target epitopes of antibodies interfering with their functional properties
Q69485751Synthesis of a (desSer1 Ile29 Leu89) chicken cystatin gene, expression in E. coli as fusion protein and its isolation
Q73901978T-kininogen present in the liver of old rats is biologically active and readily forms complexes with endogenous cysteine proteinases
Q27728538The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases
Q45956857The antifungal properties of chicken egg cystatin against Candida yeast isolates showing different levels of azole resistance.
Q68070006The complete primary structure of bovine stefin B
Q41948918The crystal structure of human dipeptidyl peptidase I (cathepsin C) in complex with the inhibitor Gly-Phe-CHN2.
Q28283958The cystatins: Protein inhibitors of cysteine proteinases
Q69611059The cysteine proteinase inhibitor chicken cystatin is a phosphoprotein
Q28282395The cysteine proteinases of the pineapple plant
Q47748837The effect of meat quality, salt and ageing time on biochemical parameters of dry-cured Longissimus dorsi muscle.
Q35749134The major transition state in folding need not involve the immobilization of side chains
Q24300962The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors
Q24556546The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction
Q71786703The removal of 2-oxoacyl residues from the N-terminus of peptides and cystatin in non-denaturing conditions
Q40401867The role of vascular permeability factor and basic fibroblast growth factor in tumor angiogenesis
Q27634658Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily
Q38342347Transcriptomic analysis in the leech Theromyzon tessulatum: involvement of cystatin B in innate immunity.
Q36888942UDP-GlcNAc:Ser-protein N-acetylglucosamine-1-phosphotransferase from Dictyostelium discoideum recognizes serine-containing peptides and eukaryotic cysteine proteinases

Search more.