A single-amino acid substitution in a gamma-aminobutyric acid subtype A receptor locus is associated with cyclodiene insecticide resistance in Drosophila populations

scientific article

A single-amino acid substitution in a gamma-aminobutyric acid subtype A receptor locus is associated with cyclodiene insecticide resistance in Drosophila populations is …
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scholarly articleQ13442814

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P819ADS bibcode1993PNAS...90.1957F
P356DOI10.1073/PNAS.90.5.1957
P932PMC publication ID45999
P698PubMed publication ID8095336
P5875ResearchGate publication ID15104588

P50authorRichard ffrench-ConstantQ41847859
P2093author name stringR T Roush
K Aronstein
J C Steichen
T A Rocheleau
P2860cites workGene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.)Q28333319
Acetylcholinesterase. Two types of modifications confer resistance to insecticideQ33227330
Sequence of a functional invertebrate GABAA receptor subunit which can form a chimeric receptor with a vertebrate alpha subunitQ35933008
Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate gamma-aminobutyric acid subtype A receptor locus.Q37579965
Receptors for gamma-aminobutyric acid and voltage-dependent chloride channels as targets for drugs and toxicantsQ38179155
Improved detection of insecticide resistance through conventional and molecular techniquesQ39757159
Worldwide migration of amplified insecticide resistance genes in mosquitoes.Q41905105
Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptorQ43866558
Drosophila cyclodiene resistance gene shows conserved genomic organization with vertebrate gamma-aminobutyric acidA receptors.Q52441406
Isolation of dieldrin resistance from field populations of Drosophila melanogaster (Diptera: Drosophilidae).Q52449251
Monogenic inheritance of cyclodiene insecticide resistance in mosquitofish, Gambusia affinis.Q52464853
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectinsecticideQ181322
insecticide resistanceQ60036895
DrosophilaQ312154
P1104number of pages5
P304page(s)1957-1961
P577publication date1993-03-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleA single-amino acid substitution in a gamma-aminobutyric acid subtype A receptor locus is associated with cyclodiene insecticide resistance in Drosophila populations
P478volume90

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cites work (P2860)
Q37269707A locus in Drosophila sechellia affecting tolerance of a host plant toxin
Q35237427A pentasymmetric open channel blocker for Cys-loop receptor channels
Q60935261A review on the progress of sex-separation techniques for sterile insect technique applications against Anopheles arabiensis
Q42016316A single major QTL controls expression of larval Cry1F resistance trait in Ostrinia nubilalis (Lepidoptera: Crambidae) and is independent of midgut receptor genes
Q28367616A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms
Q42282924Actions of picrodendrin antagonists on dieldrin-sensitive and -resistant Drosophila GABA receptors
Q42708156Actions of the insecticide fipronil, on dieldrin‐sensitive and ‐resistant GABA receptors of Drosophila melanogaster
Q36815237Affordable assays for genotyping single nucleotide polymorphisms in insects
Q41983842Agonist pharmacology of two Drosophila GABA receptor splice variants
Q24683607Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification
Q46818563An ionotropic GABA receptor in cultured mushroom body Kenyon cells of the honeybee and its modulation by intracellular calcium
Q40715400Cloning and sequencing of the cyclodiene insecticide resistance gene from the yellow fever mosquito Aedes aegypti. Conservation of the gene and resistance associated mutation with Drosophila.
Q37088829Cloning, expression analysis, and molecular modeling of the gamma-aminobutyric acid receptor alpha2 subunit gene from the common cutworm, Spodoptera litura
Q38558791Conservation of cyclodiene insecticide resistance-associated mutations in insects.
Q56930840Cross resistance between insecticides in coffee berry borer, Hypothenemus hampei (Coleoptera: Scolytidae) from New Caledonia
Q33746235Cytochromes P450 and insecticide resistance
Q51201852Discovery of the Rdl mutation in association with a cyclodiene resistant population of horn flies, Haematobia irritans (Diptera: Muscidae).
Q41513150Ecogenetics: from ecology to health.
Q44144584Effects of the essential oils of Lippia turbinata and Lippia polystachya (Verbenaceae) on the temporal pattern of locomotion of the mosquito Culex quinquefasciatus (Diptera: Culicidae) larvae.
Q41509312Expression of a Drosophila GABA receptor in a baculovirus insect cell system. Functional expression of insecticide susceptible and resistant GABA receptors from the cyclodiene resistance gene Rdl.
Q36682783Fipronil insecticide: novel photochemical desulfinylation with retention of neurotoxicity
Q52594665Fly-ing from genes to drugs.
Q50640704Functional characterization of Musca glutamate- and GABA-gated chloride channels expressed independently and coexpressed in Xenopus oocytes.
Q40694885Functional expression of insecticide-resistant GABA receptors from the mosquito Aedes aegypti.
Q44477223GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons.
Q37157277Gene duplication in the major insecticide target site, Rdl, in Drosophila melanogaster
Q52552329Genetic approaches to CNS disorders with particular reference to GABAA-receptor mutations.
Q36709241Global variation in the genetic and biochemical basis of diamondback moth resistance to Bacillus thuringiensis
Q41707937Heritable mutations in the glycine, GABAA, and nicotinic acetylcholine receptors provide new insights into the ligand-gated ion channel receptor superfamily.
Q41621474Homology modeling of human alpha 1 beta 2 gamma 2 and house fly beta 3 GABA receptor channels and Surflex-docking of fipronil
Q40348112Identification of a dieldrin resistance-associated mutation in Rhipicephalus (Boophilus) microplus (Acari: Ixodidae).
Q33986689Identification, analysis, and linkage mapping of expressed sequence tags from the Australian sheep blowfly
Q44751315Inheritance of resistance to flumethrin in the Mexican Aldama strain of the cattle tick Boophilus microplus (Acari: Ixodidae).
Q93606201Insect resistance to Bacillus thuringiensis: uniform or diverse
Q37092617Insecticide resistance and vector control
Q36728967Insecticide resistance resulting from an absence of target-site gene product
Q34047528Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants.
Q41241974Isolation and characterization of a dihydrofolate reductase gene mutation in methotrexate-resistant Drosophila cells.
Q41160536Knockdown of the ionotropic γ-aminobutyric acid receptor (GABAR) RDL gene decreases fipronil susceptibility of the small brown planthopper, Laodelphax striatellus (Hemiptera: Delphacidae).
Q38464075Lufenuron, a chitin-synthesis inhibitor, interrupts development of Drosophila melanogaster
Q35187767Model systems in drug discovery: chemical genetics meets genomics
Q35026741Modulation of a recombinant invertebrate gamma-aminobutyric acid receptor-chloride channel complex by isoflurane: effects of a point mutation in the M2 domain
Q41673439Molecular biology of insect neuronal GABA receptors
Q38562236Neo-Darwinian developmental evolution: can we bridge the gap between pattern and process?
Q44086531Peripheral GABAergic inhibition of spider mechanosensory afferents
Q48661788Pharmacological characterization of the Haemonchus contortus GABA-gated chloride channel, Hco-UNC-49: modulation by macrocyclic lactone anthelmintics and a receptor for piperazine
Q34597191Picrotoxin-like channel blockers of GABAA receptors
Q43049138Polymerase chain reaction diagnostic for cyclodiene insecticide resistance in the mosquito Aedes aegypti
Q111346856Resistance of Colorado potato beetle (Leptinotarsa decemlineata Say) to commonly used insecticides in Iran
Q41122023Resistance status of the Colorado potato beetle, Leptinotarsa decemlineata, to endosulfan in East Azarbaijan and Ardabil provinces of Iran
Q38922224Resistance to dieldrin + fipronil assorts with chromosome inversion 2La in the malaria vector Anopheles gambiae.
Q33628412Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain
Q38563956Single-stranded DNA conformation polymorphism at the Rdl locus in Hypothenemus hampei (Coleoptera: Scolytidae).
Q57945087Target site mediated insecticide resistance: what questions remain?
Q43621598The acetylcholinesterase gene and organophosphorus resistance in the Australian sheep blowfly, Lucilia cuprina.
Q35045966Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster
Q43580950Using model-system genetics for drug-based target discovery
Q46258888When evolution is the solution to pollution: Key principles, and lessons from rapid repeated adaptation of killifish (Fundulus heteroclitus) populations.
Q33533886Why are there so few resistance-associated mutations in insecticide target genes?