Androgen antagonistic effect of estramustine phosphate (EMP) metabolites on wild-type and mutated androgen receptor

scientific article

Androgen antagonistic effect of estramustine phosphate (EMP) metabolites on wild-type and mutated androgen receptor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-2952(97)00657-6
P698PubMed publication ID10076535

P2093author name stringX M Liu
D R Budman
L G Wang
W Kreis
P2860cites workThe steroid and thyroid hormone receptor superfamilyQ27861095
Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activationQ28284288
Clinical pharmacokinetics of estramustine phosphateQ40179005
Unique synergism or antagonism of combinations of chemotherapeutic and hormonal agents in human prostate cancer cell linesQ41130409
Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancerQ41344070
Effects of antiandrogens on transformation and transcription activation of wild-type and mutated (LNCaP) androgen receptorsQ41510505
The promoter of the prostate-specific antigen gene contains a functional androgen responsive elementQ41655072
A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgensQ44507804
Synergism between androgens and protein kinase-C on androgen-regulated gene expressionQ44950083
The hydrolysis of estramustine phosphate; in vitro studiesQ59485409
Growth inhibiting effect of estramustine on two prostatic carcinoma cell lines, LNCaP and LNCaP-rQ67986180
Regulation of growth and epidermal growth factor receptor levels of LNCaP prostate tumor cells by different steroidsQ68100059
Distribution and metabolism of estramustine in HeLa cells and the human prostatic tumour cell line 1013LQ68462879
Effect of estramustine phosphate on the assembly of trypsin-treated microtubules and microtubules reconstituted from purified tubulin with either tau, MAP2, or the tubulin-binding fragment of MAP2Q70358146
Induction of differentiation and down-regulation of c-myb gene expression in ML-1 human myeloblastic leukemia cells by the clinically effective anti-leukemia agent meisoindigoQ71077815
Estramustine-induced mitotic arrest in two human prostatic carcinoma cell lines DU 145 and PC-3Q71264628
Hydroxyflutamide may not always be a pure antiandrogenQ73273929
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)1427-33
P577publication date1998-05-01
P1433published inBiochemical PharmacologyQ864229
P1476titleAndrogen antagonistic effect of estramustine phosphate (EMP) metabolites on wild-type and mutated androgen receptor
P478volume55

Reverse relations

cites work (P2860)
Q43740772Changes in prostate-specific antigen (PSA) level correlate with growth inhibition of prostate cancer cells treated in vitro with a novel anticancer drug, irofulven
Q40146115Coprinus comatus and Ganoderma lucidum interfere with androgen receptor function in LNCaP prostate cancer cells
Q40821551Phase I trial of the combination of daily estramustine phosphate and intermittent docetaxel in patients with metastatic hormone refractory prostate carcinoma
Q34707836Recent advances in chemotherapy for advanced prostate cancer
Q78251649Synergistic effect of estramustine and [3'-keto-Bmtl]-[Val2]-cyclosporine (PSC 833) on the inhibition of androgen receptor phosphorylation in LNCaP cells
Q30486738The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors
Q34318315The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.
Q35193278The androgen receptor: structure, mutations, and antiandrogens

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