| scholarly article | Q13442814 |
| P2093 | author name string | R A Harris | |
| R A Morrisett | |||
| W R Wilson | |||
| R D Mayfield | |||
| S J Brozowski | |||
| J M Lewohl | |||
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| IRK(1-3) and GIRK(1-4) inwardly rectifying K+ channel mRNAs are differentially expressed in the adult rat brain | Q28280082 | ||
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| Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? | Q37438358 | ||
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| Twelfth Gaddum memorial lecture. Drug receptors and the inhibition of nerve cells | Q38707891 | ||
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| Evidence that direct binding of Gβγ to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation | Q42065529 | ||
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| Actions of long chain alcohols on GABAA and glutamate receptors: relation to in vivo effects | Q42704387 | ||
| The role of protein kinase C in cellular tolerance to ethanol | Q46126245 | ||
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| G-protein-gated inward rectifier K+ channel proteins (GIRK1) are present in the soma and dendrites as well as in nerve terminals of specific neurons in the brain | Q49058691 | ||
| A region of the muscarinic-gated atrial K+ channel critical for activation by G protein beta gamma subunits | Q49090603 | ||
| Alcohols inhibit a cloned potassium channel at a discrete saturable site. Insights into the molecular basis of general anesthesia. | Q51596719 | ||
| Calcium-dependent chloride currents elicited by injection of ethanol into Xenopus oocytes | Q69361436 | ||
| Substrate specificity of alcohol dehydrogenases | Q70717226 | ||
| G beta gamma binds directly to the G protein-gated K+ channel, IKACh | Q71573436 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1084-90 | |
| P577 | publication date | 1999-12-01 | |
| P1433 | published in | Nature Neuroscience | Q1535359 |
| P1476 | title | G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action | |
| P478 | volume | 2 |
| Q40631923 | A Site of Alcohol Action in the Fourth Membrane-associated Domain of the N-Methyl-D-aspartate Receptor |
| Q42097716 | A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels. |
| Q36108725 | A conceptualization of integrated actions of ethanol contributing to its GABAmimetic profile: a commentary |
| Q24643496 | A discrete alcohol pocket involved in GIRK channel activation |
| Q34467815 | A pervasive mechanism for analgesia: activation of GIRK2 channels |
| Q37383662 | Acute alcohol action and desensitization of ligand-gated ion channels |
| Q36778516 | Acute effects of traditional Japanese alcohol beverages on blood glucose and polysomnography levels in healthy subjects |
| Q37559612 | Acute ethanol exposure inhibits silencing of cerebellar Golgi cell firing induced by granule cell axon input. |
| Q26799805 | Advances in Electrophysiological Research |
| Q34053689 | Alcohol and adult hippocampal neurogenesis: promiscuous drug, wanton effects |
| Q47901530 | Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits. |
| Q38194551 | Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics |
| Q37890000 | Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution |
| Q33787183 | Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity |
| Q22241964 | Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior |
| Q35236604 | Alcoholism: the dissection for endophenotypes |
| Q44575118 | Allosteric modulation of a neuronal K+ channel by 1-alkanols is linked to a key residue in the activation gate |
| Q37102172 | Alterations in the levels of heterotrimeric G protein subunits induced by psychostimulants, opiates, barbiturates, and ethanol: Implications for drug dependence, tolerance, and withdrawal |
| Q35120747 | Antagonists of alcohol inhibition of cell adhesion. |
| Q26783948 | Behavioral and Genetic Evidence for GIRK Channels in the CNS: Role in Physiology, Pathophysiology, and Drug Addiction |
| Q36951665 | CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels |
| Q35184533 | Cell death in weaver mouse cerebellum |
| Q36501908 | Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs |
| Q36372867 | Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse |
| Q37705765 | Deleterious effects of a low amount of ethanol on LTP-like plasticity in human cortex |
| Q41145672 | Differential Effects of Toluene and Ethanol on Dopaminergic Neurons of the Ventral Tegmental Area. |
| Q37386396 | Discovering genes involved in alcohol dependence and other alcohol responses: role of animal models |
| Q57157460 | Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) Channels |
| Q35144776 | Drosophila melanogaster, a genetic model system for alcohol research |
| Q40966038 | Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol. |
| Q41445173 | Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel |
| Q36515619 | Effect of chronic administration of ethanol on the regulation of the delta-subunit of GABA(A) receptors in the rat brain |
| Q44015282 | Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activity |
| Q44830719 | Effects of ethanol and GABAB drugs on working memory in C57BL/6J and DBA/2J mice |
| Q43660159 | Effects of ethanol on the dorsal raphe nucleus and its projections to the caudate putamen |
| Q34643934 | Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. |
| Q44422935 | Ethanol Excitation of Dopaminergic Ventral Tegmental Area Neurons Is Blocked by Quinidine |
| Q27687624 | Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs |
| Q51739075 | Ethanol actions on the ventral tegmental area: novel potential targets on reward pathway neurons. |
| Q40685010 | Ethanol alters opioid regulation of Ca(2+) influx through L-type Ca(2+) channels in PC12 cells. |
| Q37632742 | Ethanol and acetaldehyde action on central dopamine systems: mechanisms, modulation, and relationship to stress |
| Q36893200 | Ethanol effects on dopaminergic ventral tegmental area neurons during block of Ih: involvement of barium-sensitive potassium currents |
| Q34277701 | Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans |
| Q37393255 | Ethanol modulates BKCa channels by acting as an adjuvant of calcium |
| Q45163153 | Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: role of presynaptic GABA(B) receptors. |
| Q37027080 | Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons |
| Q46621162 | Ethanol triggers neural crest apoptosis through the selective activation of a pertussis toxin-sensitive G protein and a phospholipase Cbeta-dependent Ca2+ transient |
| Q37165668 | Ethanol's molecular targets |
| Q35061649 | Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA(A) receptors and has measureable metabolic effects at very low concentrations |
| Q44031828 | Ethanol-sensitive sites on the human dopamine transporter |
| Q39636612 | G protein {beta}{gamma} gating confers volatile anesthetic inhibition to Kir3 channels |
| Q46667871 | G-protein-gated potassium (GIRK) channels containing the GIRK2 subunit are control hubs for pharmacologically induced hypothermic responses. |
| Q36405967 | GABAB receptor activation attenuates the stimulant but not mesolimbic dopamine response to ethanol in FAST mice |
| Q37775217 | GABAB-GIRK2-mediated signaling in Down syndrome. |
| Q38225536 | GABAergic neurotransmission and new strategies of neuromodulation to compensate synaptic dysfunction in early stages of Alzheimer's disease |
| Q35699323 | GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol. |
| Q24677018 | Gamma-aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence |
| Q34400860 | Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayers |
| Q35046224 | General anesthetic octanol and related compounds activate wild-type and delF508 cystic fibrosis chloride channels |
| Q39101511 | Genetic studies of alcohol dependence in the context of the addiction cycle |
| Q36604310 | Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood |
| Q36953108 | Genomic insights into acute alcohol tolerance |
| Q42814470 | Identification of selective agonists and antagonists to g protein-activated inwardly rectifying potassium channels: candidate medicines for drug dependence and pain |
| Q34099069 | Inhibition of G protein-activated inwardly rectifying K+ channels by different classes of antidepressants |
| Q35045125 | Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac). |
| Q33989582 | Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil |
| Q42461849 | Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs |
| Q24602850 | Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine |
| Q33761327 | Intron 4 containing novel GABAB1 isoforms impair GABAB receptor function |
| Q24296441 | Inwardly rectifying potassium channels: their structure, function, and physiological roles |
| Q48115623 | Ivermectin activates GIRK channels in a PIP2 -dependent, Gβγ -independent manner and an amino acid residue at the slide helix governs the activation |
| Q30460166 | KCNQ channels show conserved ethanol block and function in ethanol behaviour. |
| Q59802718 | Label-Free Whole Cell Biosensing for High-Throughput Discovery of Activators and Inhibitors Targeting G Protein-Activated Inwardly Rectifying Potassium Channels |
| Q33761809 | Low dose acute alcohol effects on GABA A receptor subtypes |
| Q30492936 | Mapping a barbiturate withdrawal locus to a 0.44 Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol. |
| Q28365230 | Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels |
| Q33972094 | Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297. |
| Q35910884 | Microarray analysis identifies cerebellar genes sensitive to chronic ethanol treatment in PKCgamma mice |
| Q34191211 | Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain |
| Q37318078 | Molecular mechanism underlying ethanol activation of G-protein-gated inwardly rectifying potassium channels |
| Q34922365 | Molecular mechanisms of analgesia induced by opioids and ethanol: is the GIRK channel one of the keys? |
| Q43721038 | Mutational analysis of ethanol interactions with G-protein-coupled inwardly rectifying potassium channels |
| Q36421916 | N-Docosahexaenoylethanolamine ameliorates ethanol-induced impairment of neural stem cell neurogenic differentiation |
| Q35089876 | Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q. |
| Q22251110 | Neuropharmacology of alcohol addiction |
| Q38165545 | New insights into the therapeutic potential of Girk channels. |
| Q50213869 | Optical control of GIRK channels using visible light |
| Q37585109 | Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO). |
| Q43962704 | Oral sensation of ethanol in a primate model III: responses in the lingual branch of the trigeminal nerve of Macaca mulatta |
| Q37201611 | Pharmacogenetic treatments for drug addiction: alcohol and opiates. |
| Q31961933 | Possible involvement of Fyn kinase in ethanol-stimulated Cas tyrosine phosphorylation in rat cerebellum and cerebral cortex |
| Q34359231 | Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system |
| Q42795716 | Promitogenic effects of ethanol, methanol, and ethanolamine in insulin-treated fibroblasts. |
| Q44423342 | Reduced ethanol-induced conditioned taste aversion and conditioned place preference in GIRK2 null mutant mice |
| Q34738660 | Role of GABA abnormalities in the inferior colliculus pathophysiology - audiogenic seizures |
| Q37386501 | Shared mechanisms of alcohol and other drugs |
| Q53834764 | Structural basis for the ethanol action on G-protein-activated inwardly rectifying potassium channel 1 revealed by NMR spectroscopy. |
| Q46961785 | Structural constraints for alcohol-stimulated Ca2+ release in neural crest, and dual agonist/antagonist properties of n-octanol |
| Q30388351 | Synaptic effects induced by alcohol |
| Q36309741 | The "ups and downs" of signaling cascades in addiction |
| Q35107891 | The Selective Serotonin Reuptake Inhibitor Paroxetine, but not Fluvoxamine, Decreases Methamphetamine Conditioned Place Preference in Mice |
| Q90629306 | The intriguing effect of ethanol and nicotine on acetylcholine-sensitive potassium current IKAch: Insight from a quantitative model |
| Q21090144 | The mechanistic classification of addictive drugs |
| Q35202929 | The neurobiology and control of anxious states |
| Q38055664 | The recent progress in research on effects of anesthetics and analgesics on G protein-coupled receptors |
| Q36490541 | The residue I257 at S4-S5 linker in KCNQ1 determines KCNQ1/KCNE1 channel sensitivity to 1-alkanols |
| Q35618326 | The role of neurotransmission and the Chopper domain in p75 neurotrophin receptor death signaling |
| Q35982852 | The search for genes contributing to the low level of response to alcohol: patterns of findings across studies |
| Q38735597 | Titrating Tipsy Targets: The Neurobiology of Low-Dose Alcohol |
| Q44085593 | Two-shot cocktail: adenosine, dopamine and a twist of beta gamma |
| Q26864720 | Virogenetic and optogenetic mechanisms to define potential therapeutic targets in psychiatric disorders |
| Q40599305 | betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation |
| Q50651710 | p75 neurotrophin receptor mediates neuronal cell death by activating GIRK channels through phosphatidylinositol 4,5-bisphosphate. |
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