| scholarly article | Q13442814 |
| P50 | author | James Degregori | Q71084355 |
| P2093 | author name string | Andrii I Rozhok | |
| P2860 | cites work | EVOLUTION IN MENDELIAN POPULATIONS | Q5418627 |
| DNA methylation age of human tissues and cell types | Q21183994 | ||
| Fitness and its role in evolutionary genetics | Q22122004 | ||
| Cancer genome landscapes | Q22242276 | ||
| Hallmarks of Cancer: The Next Generation | Q22252312 | ||
| Detectable clonal mosaicism and its relationship to aging and cancer | Q23916196 | ||
| A new theory on cancer-inducing mechanism | Q24564810 | ||
| The age distribution of cancer and a multi-stage theory of carcinogenesis | Q24564904 | ||
| Mesenchymal stem cells migration homing and tracking | Q27003059 | ||
| Cell competition: how to eliminate your neighbours | Q27005925 | ||
| Somatic mutation: early cancer steps depend on tissue architecture | Q28188697 | ||
| The clonal evolution of tumor cell populations | Q28271546 | ||
| Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age? | Q28383732 | ||
| Detectable clonal mosaicism from birth to old age and its relationship to cancer | Q28385149 | ||
| Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence | Q28385712 | ||
| Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis | Q28386212 | ||
| Age-related clonal hematopoiesis associated with adverse outcomes | Q28386602 | ||
| Patterns of somatically acquired amplifications and deletions in apparently normal tissues of ovarian cancer patients | Q28390831 | ||
| Comparative genetics of longevity and cancer: insights from long-lived rodents | Q28652609 | ||
| Peto's Paradox: evolution's prescription for cancer prevention | Q28741797 | ||
| Paradoxical roles of the immune system during cancer development | Q29614305 | ||
| Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia | Q29615735 | ||
| Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells | Q29619410 | ||
| Irradiation selects for p53-deficient hematopoietic progenitors. | Q30979212 | ||
| Aging of the microenvironment influences clonality in hematopoiesis | Q31081388 | ||
| p53-mediated hematopoietic stem and progenitor cell competition. | Q33857597 | ||
| The age of cancer | Q34088387 | ||
| Evidence that the number of hematopoietic stem cells per animal is conserved in mammals | Q34150114 | ||
| Contribution of an aged microenvironment to aging-associated myeloproliferative disease | Q34171027 | ||
| Accumulation of driver and passenger mutations during tumor progression | Q34276850 | ||
| Multistage carcinogenesis and the incidence of colorectal cancer | Q34381339 | ||
| Declining lymphoid progenitor fitness promotes aging-associated leukemogenesis. | Q34411132 | ||
| Rapid accumulation of genome rearrangements in liver but not in brain of old mice | Q34449310 | ||
| Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations. | Q34662452 | ||
| The replication rate of human hematopoietic stem cells in vivo | Q34997694 | ||
| Multistage models of carcinogenesis | Q35035351 | ||
| Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect | Q35052404 | ||
| The age incidence of chronic myeloid leukemia can be explained by a one-mutation model | Q35075559 | ||
| Cancer, aging and the optimal tissue design | Q36249489 | ||
| Aging and genome maintenance | Q36357846 | ||
| An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia | Q36541505 | ||
| Mechanisms of cell competition: themes and variations | Q36695589 | ||
| Estimation of the number of mutations necessary to cause chronic myeloid leukaemia from epidemiological data | Q36813659 | ||
| Coevolution of telomerase activity and body mass in mammals: from mice to beavers | Q37069829 | ||
| Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine | Q37226538 | ||
| Irradiation alters selection for oncogenic mutations in hematopoietic progenitors. | Q37350349 | ||
| Autoimmunity as a double agent in tumor killing and cancer promotion. | Q37642271 | ||
| Inflammaging (inflammation + aging): A driving force for human aging based on an evolutionarily antagonistic pleiotropy theory? | Q37682005 | ||
| The morphology, immunohistochemistry, and incidence of hematopoietic neoplasms in mice and rats | Q40766801 | ||
| Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes. | Q41615699 | ||
| The effect of one additional driver mutation on tumor progression. | Q41846748 | ||
| Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects. | Q42681979 | ||
| Minimizing the risk of cancer: tissue architecture and cellular replication limits | Q43065072 | ||
| Age-related mutation accumulation at a lacZ reporter locus in normal and tumor tissues of Trp53-deficient mice. | Q43869194 | ||
| Intestinal stem cell replacement follows a pattern of neutral drift | Q44951523 | ||
| Evidence that hematopoiesis may be a stochastic process in vivo | Q45876111 | ||
| Law of the Minimum paradoxes. | Q51635710 | ||
| Physiological migration of hematopoietic stem and progenitor cells. | Q52126942 | ||
| Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age. | Q52373791 | ||
| Defining stem cell dynamics in models of intestinal tumor initiation. | Q53130842 | ||
| Retarded senescence in an insular population of Virginia opossums (Didelphis virginiana) | Q55890583 | ||
| BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros | Q57734316 | ||
| In vivo kinetics of murine hemopoietic stem cells | Q73172781 | ||
| Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay | Q73374085 | ||
| Evolutionary dynamics of mutator phenotypes in cancer: implications for chemotherapy | Q79219027 | ||
| Leukocyte telomere dynamics and human hematopoietic stem cell kinetics during somatic growth | Q83346611 | ||
| P433 | issue | 29 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 8914-8921 | |
| P577 | publication date | 2015-07-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations | |
| P478 | volume | 112 |
| Q64081122 | A generalized theory of age-dependent carcinogenesis |
| Q97652732 | A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution |
| Q37051745 | Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo |
| Q45902054 | Cancer and intercellular cooperation. |
| Q38737808 | Cancer and life-history traits: lessons from host-parasite interactions |
| Q89637350 | Cancer as a disease of old age: changing mutational and microenvironmental landscapes |
| Q37661123 | Cancer: A disease at the crossroads of trade-offs |
| Q33767473 | Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity |
| Q50908461 | Changing mutational and adaptive landscapes and the genesis of cancer. |
| Q53184012 | Connecting Cancer to Its Causes Requires Incorporation of Effects on Tissue Microenvironments. |
| Q91510495 | Deriving safe short-term chemical exposure values (STEV) for drinking water |
| Q94502506 | Drug-Induced Resistance in Micrometastases: Analysis of Spatio-Temporal Cell Lineages |
| Q39603486 | Emergent properties of a computational model of tumour growth |
| Q26751065 | Energy metabolic dysfunction as a carcinogenic factor in cancer cells |
| Q47607723 | Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene-induced lung tumors in aged mice |
| Q28385959 | Epithelial neoplasia coincides with exacerbated injury and fibrotic response in the lungs of Gprc5a-knockout mice following silica exposure |
| Q47104438 | Folate dietary insufficiency and folic acid supplementation similarly impair metabolism and compromise hematopoiesis. |
| Q37672703 | Hierarchical tissue organization as a general mechanism to limit the accumulation of somatic mutations |
| Q35895639 | In the light of evolution IX: Clonal reproduction: Alternatives to sex. |
| Q28383417 | Loss of Y Chromosome in Peripheral Blood of Colorectal and Prostate Cancer Patients |
| Q64963532 | Multi-stage models for the failure of complex systems, cascading disasters, and the onset of disease. |
| Q41989445 | Press-pulse: a novel therapeutic strategy for the metabolic management of cancer. |
| Q38273280 | Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions |
| Q92292066 | Relating evolutionary selection and mutant clonal dynamics in normal epithelia |
| Q60922756 | Remodeling the Microenvironment before Occurrence and Metastasis of Cancer |
| Q37414125 | Role of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stress |
| Q33565858 | Significant Prognostic Features and Patterns of Somatic TP53 Mutations in Human Cancers |
| Q28598444 | Size, longevity and cancer: age structure |
| Q92827050 | Somatic maintenance impacts the evolution of mutation rate |
| Q38702921 | Stem cells and healthy aging |
| Q28386119 | Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia |
| Q37266021 | TP53 mutation, mitochondria and cancer |
| Q39260251 | The evolution of lifespan and age-dependent cancer risk |
| Q98613072 | The three dimensions of somatic evolution: Integrating the role of genetic damage, life-history traits, and aging in carcinogenesis |
| Q90622731 | Tumour Initiation: a Discussion on Evidence for a "Load-Trigger" Mechanism |
| Q40150370 | Ultra-sensitive Sequencing Identifies High Prevalence of Clonal Hematopoiesis-Associated Mutations throughout Adult Life |
| Q38649987 | Variation in organ-specific PIK3CA and KRAS mutant levels in normal human tissues correlates with mutation prevalence in corresponding carcinomas. |
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