Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort

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Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1004930
P8608Fatcat IDrelease_x6aitselobedrhm5b7voojqucm
P3181OpenCitations bibliographic resource ID2119175
P932PMC publication ID4309593
P698PubMed publication ID25629170
P5875ResearchGate publication ID271598471

P50authorLaurel A HabelQ82880626
Stephen K Van Den EedenQ87734385
Lori C SakodaQ89685276
Catherine SchaeferQ92862391
Charles QuesenberryQ102048181
Douglas A. CorleyQ110251065
P2093author name stringNeil Risch
Ling Shen
John S Witte
Jinghua Liu
Eric Jorgenson
Lawrence H Kushi
Maryam M Asgari
Mark N Kvale
Thomas J Hoffmann
Yambazi Banda
P2860cites workA flexible and accurate genotype imputation method for the next generation of genome-wide association studiesQ21129496
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Germline mutations in HOXB13 and prostate-cancer riskQ28257179
HOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signalingQ28298697
A rare variant in MYH6 is associated with high risk of sick sinus syndromeQ28306661
Performance of genotype imputation for rare variants identified in exons and flanking regions of genesQ28744692
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Fast and accurate genotype imputation in genome-wide association studies through pre-phasingQ29614942
Rare variants create synthetic genome-wide associationsQ29614955
Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project.Q30419441
Imputation of coding variants in African Americans: better performance using data from the exome sequencing projectQ30662194
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Predictive relevance of HOXB13 protein expression for tamoxifen benefit in breast cancerQ34173474
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Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84E.Q34606248
Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancerQ57265601
Association between germline HOXB13 G84E mutation and risk of prostate cancerQ84559578
Effect of genome-wide genotyping and reference panels on rare variants imputationQ85250099
Deregulation of HOX B13 expression in urinary bladder cancer progressionQ85815600
Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputationQ34734140
Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studiesQ34849667
Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference setsQ35030986
Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancerQ35097143
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Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health InitiativeQ36136132
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Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithmQ36413365
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).Q36503369
A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancerQ36582798
HOXB13 mutations in a population-based, case-control study of prostate cancerQ36728798
HOXB13 mutation and prostate cancer: studies of siblings and aggressive diseaseQ36741627
The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trialQ36895390
Genotype-imputation accuracy across worldwide human populationsQ37156125
Association of a HOXB13 variant with breast cancerQ37588396
Uncovering the roles of rare variants in common disease through whole-genome sequencingQ37755970
Statistical power and significance testing in large-scale genetic studiesQ38205106
The homeodomain protein HOXB13 regulates the cellular response to androgensQ39773980
Genome-wide association analysis of imputed rare variants: application to seven common complex diseasesQ41820122
Confirmation of the HOXB13 G84E germline mutation in familial prostate cancerQ42269072
A population-based assessment of germline HOXB13 G84E mutation and prostate cancer riskQ44440396
HOXB13 G84E mutation in Finland: population-based analysis of prostate, breast, and colorectal cancer riskQ44708071
The G84E mutation in the HOXB13 gene is associated with an increased risk of prostate cancer in PolandQ44733776
G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysisQ45369342
Germline homeobox B13 (HOXB13) G84E mutation and prostate cancer risk in European descendants: a meta-analysis of 24,213 cases and 73, 631 controls.Q45903526
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimputationQ1660484
P304page(s)e1004930
P577publication date2015-01-28
P1433published inPLOS GeneticsQ1893441
P1476titleImputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort
P478volume11

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Q35925225A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences
Q30399616Computational Modeling of complete HOXB13 protein for predicting the functional effect of SNPs and the associated role in hereditary prostate cancer
Q42396024Correction: Imputation of the Rare HOXB13 G84E Mutation and Cancer Risk in a Large Population-Based Cohort
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