| scholarly article | Q13442814 |
| P356 | DOI | 10.4172/2161-0495.1000181 |
| P8608 | Fatcat ID | release_iv35pskpyzemtliaxbwdacs3du |
| P932 | PMC publication ID | 4060629 |
| P698 | PubMed publication ID | 24949227 |
| P5875 | ResearchGate publication ID | 261761946 |
| P50 | author | Ruben K. Dagda | Q57708033 |
| P2093 | author name string | Eppie D Rael | |
| Sardar E Gasanov | |||
| P2860 | cites work | Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells | Q23910949 |
| Cancer cell injury by cytotoxins from cobra venom is mediated through lysosomal damage | Q24534905 | ||
| Therapeutic potential of snake venom in cancer therapy: current perspectives | Q24633814 | ||
| Two forms of cytotoxin II (cardiotoxin) from Naja naja oxiana in aqueous solution: spatial structures with tightly bound water molecules | Q27619247 | ||
| Elucidation of the solution structure of cardiotoxin analogue V from the Taiwan cobra (Naja naja atra)-Identification of structural features important for the lethal action of snake venom cardiotoxins | Q27622353 | ||
| Structural basis of membrane-induced cardiotoxin A3 oligomerization | Q27640836 | ||
| Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities | Q27642198 | ||
| Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins | Q27644715 | ||
| The three-dimensional structure of bothropasin, the main hemorrhagic factor from Bothrops jararaca venom: insights for a new classification of snake venom metalloprotease subgroups | Q27652381 | ||
| Interfacial catalysis: the mechanism of phospholipase A2 | Q27681640 | ||
| Crystal structure of cobra-venom phospholipase A2 in a complex with a transition-state analogue | Q27681641 | ||
| Inflammatory events induced by Lys-49 and Asp-49 phospholipases A2 isolated from Bothrops asper snake venom: role of catalytic activity | Q45246214 | ||
| Wound exudate as a proteomic window to reveal different mechanisms of tissue damage by snake venom toxins | Q45355910 | ||
| Ultrastructural evidence for the uptake of a neurotoxic snake venom phospholipase A2 into mammalian motor nerve terminals. | Q45920271 | ||
| Backbone flexibility controls the activity and specificity of a protein-protein interface: specificity in snake venom metalloproteases | Q46083143 | ||
| Isolation of two hemorrhagic toxins from Crotalus basiliscus basiliscus (Mexican west coast rattlesnake) venom and their effect on blood clotting and complement | Q46606934 | ||
| Activation of cellular functions in macrophages by venom secretory Asp-49 and Lys-49 phospholipases A(2). | Q46638842 | ||
| Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa | Q46673260 | ||
| Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and neutralization approaches | Q46715019 | ||
| Purification and functional characterization of bothrojaractivase, a prothrombin-activating metalloproteinase isolated from Bothrops jararaca snake venom. | Q46762342 | ||
| Glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin. The sulfatide.cardiotoxin complex structure in a membrane-like environment suggests a lipid-dependent cell-penetrating mechanism for membrane binding polypept | Q46786462 | ||
| Restoration of enzymatic activity in a Ser-49 phospholipase A2 homologue decreases its Ca(2+)-independent membrane-damaging activity and increases its toxicity | Q46957861 | ||
| Central Asian cobra venom cytotoxins-induced aggregation, permeability and fusion of liposomes | Q47908498 | ||
| Chemistry and functional distribution of sulfoglycolipids | Q47926761 | ||
| Cobra venom cardiotoxin (cytotoxin) isoforms and neurotoxin: comparative potency of protein kinase C inhibition and cancer cell cytotoxicity and modes of enzyme inhibition | Q48321312 | ||
| Pre-clinical and preliminary dose-finding and safety studies to identify candidate antivenoms for treatment of envenoming by saw-scaled or carpet vipers (Echis ocellatus) in northern Nigeria. | Q50607136 | ||
| A phospholipase A2-activating protein (PLAP) stimulates human neutrophil aggregation and release of lysosomal enzymes, superoxide, and eicosanoids. | Q50888135 | ||
| Binding of cardiotoxin analogue III from Formosan cobra venom to FL cells. | Q50907805 | ||
| Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies. | Q50945141 | ||
| Novel insights into capillary vessel basement membrane damage by snake venom hemorrhagic metalloproteinases: a biochemical and immunohistochemical study. | Q52574459 | ||
| Accelerated evolution and molecular surface of venom phospholipase A2 enzymes | Q56902331 | ||
| Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue | Q27681643 | ||
| First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/collagenases | Q27731442 | ||
| Surface exposure of phosphatidylserine in pathological cells | Q28239340 | ||
| Phospholipase A2 biochemistry | Q28297979 | ||
| Hemorrhagic toxins from western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e | Q28298436 | ||
| Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases. | Q30436990 | ||
| Interaction of hemorrhagic metalloproteinases with human .alpha.2-macroglobulin | Q30441381 | ||
| Insights into and speculations about snake venom metalloproteinase (SVMP) synthesis, folding and disulfide bond formation and their contribution to venom complexity | Q30446200 | ||
| A prothrombin activator from Bothrops erythromelas (jararaca-da-seca) snake venom: characterization and molecular cloning | Q30847418 | ||
| Fusion of sphingomyelin vesicles induced by proteins from Taiwan cobra (Naja naja atra) venom. Interactions of zwitterionic phospholipids with cardiotoxin analogues. | Q30915389 | ||
| Factor X activator from Vipera lebetina snake venom, molecular characterization and substrate specificity | Q32042354 | ||
| Three-finger alpha-neurotoxins and the nicotinic acetylcholine receptor, forty years on. | Q33197124 | ||
| Factor X activator from Vipera lebetina venom is synthesized from different genes | Q33207388 | ||
| Naturally occurring disulfide-bound dimers of three-fingered toxins: a paradigm for biological activity diversification | Q33326504 | ||
| Excitement ahead: structure, function and mechanism of snake venom phospholipase A2 enzymes | Q33339804 | ||
| Molecular models of the Mojave rattlesnake (Crotalus scutulatus scutulatus) venom metalloproteinases reveal a structural basis for differences in hemorrhagic activities | Q33726161 | ||
| Anionic phospholipids, interfacial binding and the regulation of cell functions | Q33817222 | ||
| Antivenomic assessment of the immunological reactivity of EchiTAb-Plus-ICP, an antivenom for the treatment of snakebite envenoming in sub-Saharan Africa | Q33880753 | ||
| Snake cytotoxins bind to membranes via interactions with phosphatidylserine head groups of lipids | Q33895247 | ||
| The fusogenic properties of the cytotoxins of cobra venom in a model membrane system | Q33915067 | ||
| Fibrinolytic enzymes from the venoms of Agkistrodon contortrix contortrix and Crotalus basiliscus basiliscus: cleavage site specificity towards the alpha-chain of fibrin | Q34333830 | ||
| Cloning and expression of a membrane receptor for secretory phospholipases A2. | Q34348680 | ||
| Phosphatidylserine, a death knell | Q34355981 | ||
| Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures | Q34474542 | ||
| Idiopathic Parkinson's disease: a review of clinical types and pathology | Q34503526 | ||
| Differential myotoxic and cytotoxic activities of pre-synaptic neurotoxins from Papuan taipan (Oxyuranus scutellatus) and Irian Jayan death adder (Acanthophis rugosus) venoms | Q34546019 | ||
| Purification and characterization of a fibrinolytic enzyme from venom of the southern copperhead snake (Agkistrodon contortrix contortrix). | Q34871200 | ||
| Snake and snail toxins acting on nicotinic acetylcholine receptors: fundamental aspects and medical applications | Q35637410 | ||
| Inflammatory effects of snake venom myotoxic phospholipases A2. | Q35690586 | ||
| Nerve terminal damage by beta-bungarotoxin: its clinical significance | Q35745331 | ||
| Phosphatidylserine exposure and red cell viability in red cell aging and in hemolytic anemia. | Q35979479 | ||
| Snake venom fibrin(ogen)olytic enzymes | Q36121437 | ||
| Structures and functions of snake venom CLPs (C-type lectin-like proteins) with anticoagulant-, procoagulant-, and platelet-modulating activities | Q36143064 | ||
| The intriguing world of prothrombin activators from snake venom | Q36143075 | ||
| Snake venom cardiotoxins and bee venom melittin activate phospholipase C activity in primary cultures of skeletal muscle | Q44020379 | ||
| Action of two phospholipases A2 purified from Bothrops alternatus snake venom on macrophages. | Q44089638 | ||
| Fibrolase, an active thrombolytic enzyme in arterial and venous thrombosis model systems. | Q44634811 | ||
| An unusual phospholipase A₂ from puff adder Bitis arietans venom--a novel blocker of nicotinic acetylcholine receptors | Q44918163 | ||
| Isolation and characterization of a cytotoxin P4 from the venom of Naja nigricollis nigricollis preferentially active on tumor cells | Q44945745 | ||
| Mojave toxin in venom of Crotalus helleri (Southern Pacific Rattlesnake): molecular and geographic characterization | Q45121013 | ||
| Comparative study of structure and activity of cytotoxins from venom of the cobras Naja oxiana, Naja kaouthia, and Naja haje. | Q45139933 | ||
| Structural basis of citrate-dependent and heparan sulfate-mediated cell surface retention of cobra cardiotoxin A3. | Q45182274 | ||
| Binding of Nucleotide Triphosphates to Cardiotoxin Analogue II from the Taiwan Cobra Venom (Naja naja atra) | Q57836437 | ||
| Mojave rattlesnakes (Crotalus scutulatus scutulatus) lacking the acidic subunit DNA sequence lack Mojave toxin in their venom | Q61847177 | ||
| Calcium Influx and Mitochondrial Alterations at Synapses Exposed to Snake Neurotoxins or Their Phospholipid Hydrolysis Products | Q63408246 | ||
| Prothrombin activation induced by ecarin - A prothrombin converting enzyme from echis carinatus venom | Q66911360 | ||
| Binding of cytotoxin P4 from Naja nigricollis nigricollis to B16F10 melanoma and WEHI-3B leukemia cells | Q67570041 | ||
| Intermembrane exchange of lipids induced by cobra venom cytotoxins | Q68079566 | ||
| Fibrinolytic proteases in snake venoms | Q68405870 | ||
| Identification and purification of a very high affinity binding protein for toxic phospholipases A2 in skeletal muscle | Q68461520 | ||
| alpha 2-macroglobulin traps a proteinase in the midregion of its arms. An immunoelectron microscopic study | Q69052964 | ||
| Cobra cardiotoxins. Purification, effects on skeletal muscle and structure/activity relationships [published errtum appears in Eur J Biochem 1988 Feb 1;171(3):727] | Q69056700 | ||
| Identification and properties of very high affinity brain membrane-binding sites for a neurotoxic phospholipase from the taipan venom | Q69351278 | ||
| [Interaction of cobra venom cytotoxin with oriented phospholipid multi-bilayers] | Q70142125 | ||
| A new class of phospholipases A2 with lysine in place of aspartate 49. Functional consequences for calcium and substrate binding | Q70507006 | ||
| Membrane disintegration and hemolysis of human erythrocytes by snake venom cardiotoxin (a membrane-disruptive polypeptide) | Q70612336 | ||
| Isolation and characterization of carinactivase, a novel prothrombin activator in Echis carinatus venom with a unique catalytic mechanism | Q71049025 | ||
| Cellular and mitochondrial changes induced in the structure of murine skeletal muscle by crotoxin, a neurotoxic phospholipase A2 complex | Q71341420 | ||
| Dissociation of enzymatic activity from lethality and pharmacological properties by carbamylation of lysines in Naja nigricollis and Naja naja atra snake venom phospholipases A2 | Q71576268 | ||
| Phospholipase A2 and cobra venom cytotoxin Vc5 interactions and membrane structure | Q71627404 | ||
| In vitro evaluation of Pyrularia thionin-anti-CD5 immunotoxin | Q71707790 | ||
| Myotoxic activity of the toxic phospholipase, notexin, from the venom of the Australian tiger snake | Q71866621 | ||
| Refined 2.0 A X-ray crystal structure of the snake venom zinc-endopeptidase adamalysin II. Primary and tertiary structure determination, refinement, molecular structure and comparison with astacin, collagenase and thermolysin | Q72003150 | ||
| Evidence that meizothrombin is an intermediate product in the clotting of whole blood | Q72294564 | ||
| Studies on the complex between human and Crotalus adamanteus proteinase II. Release of active proteinase from the complex | Q72624372 | ||
| Modulation of phospholipase A2 activity by membrane-active peptides on liposomes of different phospholipid composition | Q72630147 | ||
| Hemorrhagic and Mojave toxins in the venoms of the offspring of two Mojave rattlesnakes (Crotalus scutulatus scutulatus) | Q72708681 | ||
| Thrombolytic effects of recombinant fibrolase or APSAC in a canine model of carotid artery thrombosis | Q72791775 | ||
| Modification of phospholipid membrane structure by the plant toxic peptide Pyrularia thionin | Q72961268 | ||
| The amino acid region 115-119 of ammodytoxins plays an important role in neurotoxicity | Q73067326 | ||
| Cobra venom cytotoxin free of phospholipase A2 and its effect on model membranes and T leukemia cells | Q73107630 | ||
| Differences in fibrinolysis and complement inactivation by venom from different northern blacktailed rattlesnakes (Crotalus molossus molossus) | Q73303285 | ||
| Structures of heparin-derived tetrasaccharide bound to cobra cardiotoxins: heparin binding at a single protein site with diverse side chain interactions | Q80764913 | ||
| Hemorrhagic activity of the vascular apoptosis-inducing proteins VAP1 and VAP2 from Crotalus atrox | Q81703232 | ||
| Invited commentary. Efficacy and safety of alfimeprase in patients with acute peripheral arterial occlusion (PAO) | Q83144308 | ||
| Alfimeprase for the treatment of acute peripheral arterial occlusion | Q94696833 | ||
| Practical applications of snake venom toxins in haemostasis | Q36143100 | ||
| Snake venom metalloproteases--structure and function of catalytic and disintegrin domains | Q36376643 | ||
| Phosphatidic acid- and phosphatidylserine-binding proteins | Q36453653 | ||
| Snakebite nephropathy | Q36609884 | ||
| cDNA cloning and deduced amino acid sequence of prothrombin activator (ecarin) from Kenyan Echis carinatus venom | Q36715062 | ||
| Mitochondrial proteolipids | Q36758496 | ||
| Serpins in thrombosis, hemostasis and fibrinolysis | Q36884340 | ||
| Genetic Basis for Variation of Metalloproteinase-Associated Biochemical Activity in Venom of the Mojave Rattlesnake (Crotalus scutulatus scutulatus). | Q37101222 | ||
| Three-dimensional domain architecture of the ADAM family proteinases | Q37244846 | ||
| The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease | Q37455021 | ||
| Snakebite envenomation and death in the developing world. | Q37502969 | ||
| Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis | Q37862381 | ||
| Inhibition of phospholipase A2 by uteroglobin and antiflammin peptides | Q37868131 | ||
| Snake venom metalloproteinases: structure, function and relevance to the mammalian ADAM/ADAMTS family proteins | Q37870424 | ||
| Immune response towards snake venoms | Q37913413 | ||
| Fibrolase: trials and tribulations | Q37954287 | ||
| Snake venom metalloproteinases | Q38045664 | ||
| Structure and dynamics of cardiotoxins | Q38045944 | ||
| Phospholipases A2: unveiling the secrets of a functionally versatile group of snake venom toxins | Q38048397 | ||
| Cobra cardiotoxins: membrane interactions and pharmacological potential | Q38158055 | ||
| Active-site mutagenesis of a Lys49-phospholipase A2: biological and membrane-disrupting activities in the absence of catalysis | Q38292301 | ||
| Neutralizing interaction between heparins and myotoxin II, a lysine 49 phospholipase A2 from Bothrops asper snake venom. Identification of a heparin-binding and cytolytic toxin region by the use of synthetic peptides and molecular modeling. | Q38302217 | ||
| A model to explain the pharmacological effects of snake venom phospholipases A2. | Q38664430 | ||
| The anticancer effect of cytotoxin 1 from Naja atra Cantor venom is mediated by a lysosomal cell death pathway involving lysosomal membrane permeabilization and cathepsin B release | Q39147019 | ||
| Acute renal failure after Crotalus durissus snakebite: a prospective survey on 100 patients | Q39357094 | ||
| Structure and pharmacology of elapid cytotoxins | Q39628032 | ||
| Proteinase K-resistant alpha-synuclein is deposited in presynapses in human Lewy body disease and A53T alpha-synuclein transgenic mice | Q39722484 | ||
| Efficacy and safety of alfimeprase in patients with acute peripheral arterial occlusion (PAO). | Q39905616 | ||
| Role of glycosphingolipid conformational change in membrane pore forming activity of cobra cardiotoxin | Q40071561 | ||
| Amphiphilic beta-sheet cobra cardiotoxin targets mitochondria and disrupts its network | Q40416049 | ||
| Alpha-synuclein up-regulates expression of caveolin-1 and down-regulates extracellular signal-regulated kinase activity in B103 neuroblastoma cells: role in the pathogenesis of Parkinson's disease | Q40642550 | ||
| Possible mechanisms of action of cobra snake venom cardiotoxins and bee venom melittin | Q40830596 | ||
| Three-dimensional structures of neurotoxins and cardiotoxins | Q40847242 | ||
| Snake venom cardiotoxins-structure, dynamics, function and folding | Q40872119 | ||
| Heart and T-lymphocyte cell surfaces both exhibit positive cooperativity in binding a membrane-lytic toxin | Q41222180 | ||
| Contribution of bee venom phospholipase A2 contamination in melittin fractions to presumed activation of tissue phospholipase A2. | Q41241341 | ||
| Characterization of the inactive fragment resulting from limited proteolysis of human alpha1-proteinase inhibitor by Crotalus adamanteus proteinase II. | Q41629227 | ||
| Membrane interactions of amphiphilic polypeptides mastoparan, melittin, polymyxin B, and cardiotoxin. Differential inhibition of protein kinase C, Ca2+/calmodulin-dependent protein kinase II and synaptosomal membrane Na,K-ATPase, and Na+ pump and di | Q41695494 | ||
| Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper | Q42459179 | ||
| Pathogenesis of hemorrhage induced by bilitoxin, a hemorrhagic toxin isolated from the venom of the common cantil (Agkistrodon bilineatus bilineatus). | Q42481849 | ||
| Pathogenesis of hemorrhage induced by hemorrhagic proteinase IV from timber rattlesnake (Crotalus horridus horridus) venom | Q42517098 | ||
| Mass spectrometry analysis of the phospholipase A(2) activity of snake pre-synaptic neurotoxins in cultured neurons. | Q43284922 | ||
| Involvement of specific integrins in apoptosis induced by vascular apoptosis-inducing protein 1. | Q43872597 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | snake venom | Q424200 |
| snake | Q2102 | ||
| pharmacology | Q128406 | ||
| P304 | page(s) | 1000181 | |
| P577 | publication date | 2014-01-25 | |
| P1433 | published in | Journal of clinical toxicology | Q26839864 |
| P1476 | title | Snake Venom Cytotoxins, Phospholipase A2s, and Zn(2+)-dependent Metalloproteinases: Mechanisms of Action and Pharmacological Relevance | |
| P478 | volume | 4 |
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