Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis

scientific article

Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.00723-10
P932PMC publication ID3133224
P698PubMed publication ID21343341

P2093author name stringRama K Mallampalli
Bill B Chen
Jennifer R Glasser
Tiffany A Coon
P2860cites workThe F-box protein family.Q21194893
Identification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeatsQ22010611
Identification of a family of human F-box proteinsQ22010703
A family of mammalian F-box proteinsQ22010704
Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumoniaQ23918727
Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replicationQ24302046
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerQ24648025
Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domainQ28119149
Sequence motifs for calmodulin recognitionQ28237401
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulinQ28247685
Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activationQ28292768
F-box proteins: the key to protein degradationQ28296039
Calmodulin binds and stabilizes the regulatory enzyme, CTP: phosphocholine cytidylyltransferaseQ28578252
Implication of the F-Box Protein FBXL21 in circadian pacemaker function in mammalsQ33379609
The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU.Q35107685
Membrane traffic: GGAs sort ubiquitinQ35761474
The novel functions of ubiquitination in signalingQ35804780
E3 ubiquitin ligases as regulators of membrane protein trafficking and degradationQ36121124
Ca(2+)-dependent proteolysis in muscle wasting.Q36127683
Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathwayQ36846031
Myofibrillar protein turnover: the proteasome and the calpainsQ36914804
Oxidized lipoproteins inhibit surfactant phosphatidylcholine synthesis via calpain-mediated cleavage of CTP:phosphocholine cytidylyltransferaseQ37401562
15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferaseQ39963327
Human adenovirus modulates surfactant phospholipid traffickingQ40076000
Proapoptotic effects of P. aeruginosa involve inhibition of surfactant phosphatidylcholine synthesisQ40251529
Effects of polycations on pulmonary vascular permeability in conscious sheepQ40379846
Tumor necrosis factor-alpha inhibits expression of CTP:phosphocholine cytidylyltransferase.Q40891313
Effects of Altered Phosphorylation Sites on the Properties of CTP:Phosphocholine CytidylyltransferaseQ41323331
Masking of a nuclear signal motif by monoubiquitination leads to mislocalization and degradation of the regulatory enzyme cytidylyltransferaseQ41761558
The regulatory role of calmodulin in the proteolysis of individual neurofilament proteins by calpainQ41911299
Inhibition of autophagy causes tau proteolysis by activating calpain in rat brainQ41939339
Transcriptional regulation of lung cytidylyltransferase in developing transgenic mice.Q42000596
Calmodulin antagonist W-7 inhibits de novo synthesis of cholesterol and suppresses secretion of de novo synthesized and preformed lipids from cultured hepatocytesQ44907203
Adenoviral gene transfer of a mutant surfactant enzyme ameliorates pseudomonas-induced lung injury.Q45856453
Ca2+‐dependent ubiquitination of calmodulin in yeastQ67485652
Mapping of the calpain proteolysis products of the junctional foot protein of the skeletal muscle triad junctionQ67504778
Expression of a calmodulin inhibitor peptide in progenitor alveolar type II cells disrupts lung developmentQ71435865
Both proteasomes and lysosomes degrade the activated erythropoietin receptorQ80546895
SnapShot: F box proteins IQ84067256
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
F-box and leucine-rich repeat protein 2Q21495694
Cullin 1Q21981310
Ring-box 1Q21987468
Phosphate cytidylyltransferase 1, choline, alpha isoformQ21990438
P304page(s)1905-20
P577publication date2011-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleCalmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis
P478volume31

Reverse relations

cites work (P2860)
Q33819289A CULLINary ride across the secretory pathway: more than just secretion
Q36781352A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation
Q58245861A novel F-box protein with leucine-rich repeats affects defecation frequency and daumone response inCaenorhabditis elegans
Q35150069Acyl-CoA:lysophosphatidylcholine acyltransferase I (Lpcat1) catalyzes histone protein O-palmitoylation to regulate mRNA synthesis
Q37272000Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins.
Q58179880CFL-1, a novel F-box protein with leucine-rich repeat may interact with UNC-10 for the regulation of defecation and daumone response in Caenorhabditis elegans
Q36091846Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal
Q28395452Calmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis
Q36407323Cleavage of Signal Regulatory Protein α (SIRPα) Enhances Inflammatory Signaling
Q28389630E3 ligase subunit Fbxo15 and PINK1 kinase regulate cardiolipin synthase 1 stability and mitochondrial function in pneumonia
Q28396057F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest
Q28383185F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferation
Q36347238F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7
Q42854569F-box protein substrate recognition: a new insight
Q28396015FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest
Q24338848FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade
Q92826515GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase
Q37935680How ubiquitination regulates the TGF-β signalling pathway: new insights and new players: new isoforms of ubiquitin-activating enzymes in the E1-E3 families join the game
Q36178060Hypoxia-induced migration in pulmonary arterial smooth muscle cells requires calcium-dependent upregulation of aquaporin 1
Q35995064Identification of C-terminal Hsp70-interacting protein as a mediator of tumour necrosis factor action in osteoblast differentiation by targeting osterix for degradation
Q28385337LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1
Q36170497Lipopolysaccharide triggers nuclear import of Lpcat1 to regulate inducible gene expression in lung epithelia
Q37738018Low-intensity pulsed ultrasound (LIPUS) prevents periprosthetic inflammatory loosening through FBXL2-TRAF6 ubiquitination pathway
Q38776083Nedd8 modification of Cullin-5 regulates lipopolysaccharide-induced acute lung injury
Q37182870New insights on the function of SCF ubiquitin E3 ligases in the lung
Q42270235Phospholipid synthesis participates in the regulation of diacylglycerol required for membrane trafficking at the Golgi complex
Q34628087SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation
Q38267996SCF ubiquitin ligase-targeted therapies.
Q36647292SCF(Fbxw15) mediates histone acetyltransferase binding to origin recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate cell proliferation
Q28388125Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis
Q36600976Small molecule therapeutics targeting F-box proteins in cancer
Q28392009Targeting F box protein Fbxo3 to control cytokine-driven inflammation
Q37307538The emerging role of the ubiquitin proteasome in pulmonary biology and disease
Q28383410The proinflammatory role of HECTD2 in innate immunity and experimental lung injury
Q35097070The ubiquitin E3 ligase SCF-FBXO24 recognizes deacetylated nucleoside diphosphate kinase A to enhance its degradation
Q92932013Tumor suppressive Ca2+ signaling is driven by IP3 receptor fitness
Q38724896UBE3B Is a Calmodulin-regulated, Mitochondrion-associated E3 Ubiquitin Ligase.
Q35811448Ubiquitination and proteolysis in acute lung injury
Q41618935miRNA-346 promotes proliferation, migration and invasion in liver cancer

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