Chronic matrix metalloproteinase inhibition retards age-associated arterial proinflammation and increase in blood pressure

scientific article

Chronic matrix metalloproteinase inhibition retards age-associated arterial proinflammation and increase in blood pressure is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/HYPERTENSIONAHA.112.191270
P3181OpenCitations bibliographic resource ID4381534
P932PMC publication ID3537179
P698PubMed publication ID22689745

P50authorEdward G. LakattaQ32985045
P2093author name stringJing Zhang
James Wu
Mark Talan
Mingyi Wang
Kapil Kapoor
Liqun Jiang
Richard Telljohann
Robert E Monticone
P2860cites workIncreased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteriesQ23909575
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Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodelingQ33930863
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Arterial aging and subclinical arterial disease are fundamentally intertwined at macroscopic and molecular levelsQ34144489
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Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly.Q34542211
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Treatment of hypertension in patients 80 years of age or olderQ34766135
Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with agingQ34981297
Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young ratsQ35085406
Matrix metalloproteinase inhibitor development and the remodeling of drug discoveryQ35636536
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A Dominant Negative Inhibitor Indicates that Monocyte Chemoattractant Protein 1 Functions as a DimerQ36554378
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Inhibiting metalloproteases with PD 166793 in heart failure: impact on cardiac remodeling and beyond.Q37157939
The role of p66Shc deletion in age-associated arterial dysfunction and disease states.Q37261119
Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasionQ37394615
Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.Q40159420
Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinaseQ41646524
Arterial stiffening with ageing is associated with transforming growth factor-β1-related changes in adventitial collagen: reversal by aerobic exerciseQ42921061
Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte.Q43064761
Initial characterization of a neutral metalloproteinase, active on native 3/4-collagen fragments, synthesized by ROS 17/2.8 osteoblastic cells, periodontal fibroblasts, and identified in gingival crevicular fluidQ43653461
Coronary and aortic vasoreactivity protection with endothelin receptor antagonist, bosentan, after ischemia and hypoxia in aged ratsQ43820840
Hemodynamic patterns of age-related changes in blood pressure. The Framingham Heart StudyQ44234203
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Altered regulation of matrix metalloproteinase-2 in aortic remodeling during aging.Q54479601
Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependentQ55216617
Combination of Tumor Necrosis Factor-α Ablation and Matrix Metalloproteinase Inhibition Prevents Heart Failure After Pressure Overload in Tissue Inhibitor of Metalloproteinase-3 Knock-Out MiceQ58211733
Myocardial Infarct Expansion and Matrix Metalloproteinase InhibitionQ59651627
Proinflammatory Profile Within the Grossly Normal Aged Human Aortic WallQ63245414
Matrix Metalloproteinase 2 Activation of Transforming Growth Factor-β1 (TGF-β1) and TGF-β1–Type II Receptor Signaling Within the Aged Arterial WallQ63245415
Identification of protease(s) capable of further degrading native 3/4- and 1/4-collagen fragments generated by collagenase from native type I collagen in human neutrophilsQ69350776
Effect of chronic ANG I-converting enzyme inhibition on aging processes. II. Large arteriesQ72101596
Aerobic exercise training reduces plasma endothelin-1 concentration in older womenQ73066960
Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictorQ73175870
Matrix Metalloproteinase-3 Genotype Contributes to Age-Related Aortic Stiffening Through Modulation of Gene and Protein ExpressionQ73400898
Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive ratsQ73699573
Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failureQ73850307
Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cellsQ74254758
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)459-66
P577publication date2012-08-01
P1433published inHypertensionQ5958695
P1476titleChronic matrix metalloproteinase inhibition retards age-associated arterial proinflammation and increase in blood pressure
P478volume60

Reverse relations

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