Early-life exposure to benzo[a]pyrene increases mutant frequency in spermatogenic cells in adulthood

scientific article

Early-life exposure to benzo[a]pyrene increases mutant frequency in spermatogenic cells in adulthood is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2014PLoSO...987439X
P356DOI10.1371/JOURNAL.PONE.0087439
P932PMC publication ID3906184
P698PubMed publication ID24489914
P5875ResearchGate publication ID260063518

P2093author name stringC Alex McMahan
Christi A Walter
Guogang Xu
P2860cites workThe blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epitheliumQ93714075
Children's health and the environment: public health issues and challenges for risk assessmentQ23919545
Health and environmental consequences of the World Trade Center disasterQ23923310
Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient airQ24529932
Assessing susceptibility from early-life exposure to carcinogensQ24815464
Characterization of the dust/smoke aerosol that settled east of the World Trade Center (WTC) in lower Manhattan after the collapse of the WTC 11 September 2001Q24817081
Tobacco smoke carcinogens and lung cancerQ28140233
Every sperm is sacred--or is it?Q28264541
How are children different from adults?Q28389667
The origins of the developmental origins theoryQ29615689
Dose translation from animal to human studies revisitedQ29618049
Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterizationQ29619534
Prepubertal human spermatogonia and mouse gonocytes share conserved gene expression of germline stem cell regulatory moleculesQ33564776
Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient miceQ33588219
Environmental exposure of the mouse germ line: DNA adducts in spermatozoa and formation of de novo mutations during spermatogenesisQ33623729
Induction of cytochrome P4501A1.Q33636653
Critical windows of exposure for children's health: cancer in human epidemiological studies and neoplasms in experimental animal modelsQ33942505
Childhood exposure to secondhand smoke and functional mannose binding lectin polymorphisms are associated with increased lung cancer riskQ34183548
Mutation spectral changes in spermatogenic cells obtained from old miceQ34313516
Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.Q34399850
Air pollution induces heritable DNA mutationsQ34414772
Second hand smoke, age of exposure and lung cancer riskQ34587020
Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissuesQ34663619
A critical evaluation of DNA adducts as biological markers for human exposure to polycyclic aromatic compounds.Q35051084
Nucleotide excision repair in rat male germ cells: low level of repair in intact cells contrasts with high dual incision activity in vitroQ35091162
Sidestream tobacco smoke is a male germ cell mutagenQ35149695
Parental smoking in childhood and adult obstructive lung disease: results from the European Community Respiratory Health SurveyQ35573143
Spermatogonial stem cells of the testisQ35906981
Mutation frequency declines during spermatogenesis in young mice but increases in old miceQ36283159
Molecular mechanisms of mammalian global genome nucleotide excision repair.Q36389623
Degeneration of germ cells in normal, hypophysectomized and hormone treated hypophysectomized ratsQ36785124
Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNAQ36868866
Recovery of a low mutant frequency after ionizing radiation-induced mutagenesis during spermatogenesisQ36891621
Multilocus DNA fingerprinting reveals high rate of heritable genetic mutation in herring gulls nesting in an industrialized urban siteQ37227055
Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic miceQ37592150
Children's health and the environment: an overviewQ37831848
Reduction of particulate air pollution lowers the risk of heritable mutations in miceQ39685092
Sertoli cell junctions: morphological and functional correlatesQ39824950
Spontaneous mutation in Big Blue mice from fetus to old age: tissue-specific time courses of mutation frequency but similar mutation typesQ40528537
Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metaboliteQ40700833
Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic studyQ40845183
DNA adducts in human carcinogenesis: etiological relevance and structure-activity relationshipQ41022838
Stage-specific signals in germ line differentiation: control of Sertoli cell phagocytic activity by spermatogenic cellsQ41118247
A transversion mutation hypothesis for chemical carcinogenesis by N2-substitution of guanine in DNA.Q41645470
Morphological and histometric study of human spermatogonia from birth to the onset of puberty.Q42458317
Postnatal development of the Sertoli cell barrier, tubular lumen, and cytoskeleton of Sertoli and myoid cells in the rat, and their relationship to tubular fluid secretion and flowQ42646663
Molecular cloning of CYP1A gene and its expression by benzo(a)pyrene from goldfish (Carassius auratus).Q42663234
The transgenerational impact of benzo(a)pyrene on murine male fertilityQ42930017
Age-related changes in hepatic expression and activity of cytochrome P450 in male rats.Q43174287
DNA adduct kinetics in reproductive tissues of DNA repair proficient and deficient male mice after oral exposure to benzo(a)pyrene.Q45919161
Nucleotide excision repair activity varies among murine spermatogenic cell typesQ46367896
Disparities in secondhand smoke exposure--United States, 1988-1994 and 1999-2004.Q46492465
Mutations induced by benzo[a]pyrene and dibenzo[a,l]pyrene in lacI transgenic B6C3F1 mouse lung result from stable DNA adducts.Q46523206
The Big Blue(R) transgenic mouse mutation detection assay: the mutation pattern of sectored mutant plaquesQ47605363
Spontaneous mutations in the Big Blue transgenic system are primarily mouse derivedQ47607298
LacI mutation spectra following benzo[a]pyrene treatment of Big Blue mice.Q50513019
Spontaneous mutation in Big Blue transgenic mice: analysis of age, gender, and tissue type.Q50753712
Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium.Q51329313
Study in vitro of the phagocytic function of Sertoli cells in the ratQ67994762
The phagocytic function of Sertoli cells: a morphological, biochemical, and endocrinological study of lysosomes and acid phosphatase localization in the rat testisQ69616923
Gamma-radiation-induced mutation spectrum in the episomal lacI gene of Escherichia coli under oxic conditionsQ70998473
Infertility in mice exposed in utero to benzo(a)pyreneQ71506189
Purification, culture, and fractionation of spermatogenic cellsQ72583949
Lack of association between induction of dominant-lethal mutations and induction of heritable translocations with benzo[a]pyrene in postmeiotic germ cells of male miceQ72937425
Children and increased susceptibility to environmental carcinogens: evidence or empathy?Q75205425
Detection of benzo(a)pyrene diol epoxide-DNA adducts in sperm of men exposed to cigarette smokeQ78103158
Evaluation of benzo(a)pyrene-induced gene mutations in male germ cellsQ85229679
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)e87439
P577publication date2014-01-01
P1433published inPLOS OneQ564954
P1476titleEarly-life exposure to benzo[a]pyrene increases mutant frequency in spermatogenic cells in adulthood
P478volume9

Reverse relations

cites work (P2860)
Q93027449A Return to the Origin of the EMGS: Rejuvenating the Quest for Human Germ Cell Mutagens and Determining the Risk to Future Generations
Q42101489Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia.
Q92758739Development of broad-acting clays for the tight adsorption of benzo[a]pyrene and aldicarb
Q40175200Dose-response mutation and spectrum analyses reveal similar responses at two microsatellite loci in benzo(a)pyrene-exposed mouse spermatogonia.
Q37733372Evaluation of in vivo mutagenesis for assessing the health risk of air pollutants
Q36863290Genetic Effect of Chemotherapy Exposure in Children of Testicular Cancer Survivors
Q41829529Next generation sequencing of benzo(a)pyrene-induced lacZ mutants identifies a germ cell-specific mutation spectrum.

Search more.