Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s

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Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1005633
P3181OpenCitations bibliographic resource ID1534805
P932PMC publication ID4686043
P698PubMed publication ID26683624
P5875ResearchGate publication ID287482749

P50authorHarvey I PassQ51800337
Michele CarboneQ29998675
Francine BaumannQ29998677
Mary HesdorfferQ29998680
Giovanni GaudinoQ29998682
Sandra PastorinoQ29998683
Andrea NapolitanoQ30347581
Todd A. JohnsonQ37630313
Michaela B. KirschnerQ37838108
P2093author name stringTatsuhiko Tsunoda
Mitsuru Emi
Haining Yang
Walter Weder
Amy Powers
Olivia Lauk
Isabelle Opitz
Masaki Nasu
Erin G Flores
Peter Bryant-Greenwood
Michael Minaai
Dusty Behner
Harriet Hoffman
P2860cites workPrevalence of BRCA-1 associated protein 1 germline mutation in sporadic malignant pleural mesothelioma cases.Q51678043
Modern criteria to establish human cancer etiology.Q53286744
BAP1 and BRAFV600E expression in benign and malignant melanocytic proliferations.Q53675449
Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesisQ57755309
Confounding from cryptic relatedness in case-control association studiesQ21092505
An integrated map of genetic variation from 1,092 human genomesQ22122153
High incidence of somatic BAP1 alterations in sporadic malignant mesotheliomaQ24170431
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUBQ24309403
BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localizationQ24337105
An emerging model for BAP1's role in regulating cell cycle progressionQ24599005
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expressionQ24633127
Germline BAP1 mutations predispose to malignant mesotheliomaQ24635326
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
Principal components analysis corrects for stratification in genome-wide association studiesQ27860975
Minimal asbestos exposure in germline BAP1 heterozygous mice is associated with deregulated inflammatory response and increased risk of mesotheliomaQ28389071
Analysis of BAP1 Germline Gene Mutation in Young Uveal Melanoma PatientsQ30382522
A high-performance computing toolset for relatedness and principal component analysis of SNP dataQ30573123
Detecting identity by descent and estimating genotype error rates in sequence dataQ30691220
Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancersQ34218657
BAP1 loss defines a new class of renal cell carcinomaQ34280223
Haplotype estimation using sequencing readsQ34375384
Mesothelioma patients with germline BAP1 mutations have 7-fold improved long-term survival.Q34917972
BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITsQ36384018
BAP1 and cancerQ37221089
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repairQ37474898
Multiple primary cancers as a guide to heritabilityQ38221583
Germline mutations in BAP1 impair its function in DNA double-strand break repairQ38988548
Germline BAP1 mutations predispose also to multiple basal cell carcinomas.Q42463261
Asbestos is not just asbestos: an unrecognised health hazardQ44719750
Genetic-susceptibility factor and malignant mesothelioma in the Cappadocian region of TurkeyQ47322651
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)e1005633
P577publication date2015-12-01
P1433published inPLOS GeneticsQ1893441
P1476titleCombined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s
P478volume11

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cites work (P2860)
Q58096223A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations
Q64927500Analyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos.
Q39321847Ancestry Testing and the Practice of Genetic Counseling
Q89458226BAP1 Germline Mutation Associated with Bilateral Primary Uveal Melanoma
Q39290955BAP1 mutations in high-grade meningioma: implications for patient care
Q59126392BAP1 regulates different mechanisms of cell death
Q90612183BAP1: role in carcinogenesis and clinical implications
Q90281138Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide
Q27908468Consensus report of the 2015 Weinman International Conference on Mesothelioma
Q57461758Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine
Q55665416Detecting germline BAP1 mutations in patients with peritoneal mesothelioma: benefits to patient and family members.
Q26748767Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis
Q91897698Effects of marker type and filtering criteria on Q ST-F ST comparisons
Q40553616Environmental risk of mesothelioma in the United States: An emerging concern-epidemiological issues
Q47972869Genotypic and Phenotypic Features of BAP1 Cancer Syndrome: A Report of 8 New Families and Review of Cases in the Literature.
Q38805682Germline BAP1 alterations in familial uveal melanoma.
Q38700344Germline BAP1 mutations induce a Warburg effect
Q28395181High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma
Q90612169How asbestos and other fibers cause mesothelioma
Q39051001Improving the Accuracy of Mesothelioma Diagnosis in China
Q38429562Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma.
Q47672873Loss of BRCA1-associated protein 1 (BAP1) expression is useful in diagnostic cytopathology of malignant mesothelioma in effusions
Q39366003Malignant Mesothelioma: Time to Translate?
Q57814182Mesothelial to mesenchyme transition as a major developmental and pathological player in trunk organs and their cavities
Q33871606Mesothelioma: recent highlights
Q52581757New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma.
Q55455186Overview of BAP1 cancer predisposition syndrome and the relationship to uveal melanoma.
Q29248126Positive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesothelioma
Q52663125Progress in the Management of Malignant Pleural Mesothelioma in 2017.
Q90612176SV40 and human mesothelioma
Q58553501Sensitivity to asbestos is increased in patients with mesothelioma and pathogenic germline variants in BAP1 or other DNA repair genes
Q26738488Software for Apportionment of Asbestos-Related Mesotheliomas
Q29248727Switching off malignant mesothelioma: exploiting the hypoxic microenvironment
Q47133472Targeting microRNA to improve diagnostic and therapeutic approaches for malignant mesothelioma
Q33871638The Cappadocia mesothelioma epidemic: its influence in Turkey and abroad
Q96022920Tumour predisposition and cancer syndromes as models to study gene-environment interactions

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