Matrix metalloproteinase-8 mediates the unfavorable systemic impact of local irradiation on pharmacokinetics of anti-cancer drug 5-Fluorouracil

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Matrix metalloproteinase-8 mediates the unfavorable systemic impact of local irradiation on pharmacokinetics of anti-cancer drug 5-Fluorouracil is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...621000H
P356DOI10.1371/JOURNAL.PONE.0021000
P932PMC publication ID3111455
P698PubMed publication ID21695264
P5875ResearchGate publication ID51240427

P50authorLi-Ying WangQ57614171
P2093author name stringChen-Hsi Hsieh
Chia-Yuan Liu
Hung-Chi Tai
Tung-Hu Tsai
Yen-Ju Hsieh
Yu-Jen Chen
P2860cites workRadiation-induced bystander effects--implications for cancer.Q53370770
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Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: results from NSABP protocol R-01Q68125681
Nonlinear pharmacokinetics of 5-fluorouracil in ratsQ73426684
Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5,6-dihydrouracil after conventional and reduced test dose in cancer patientsQ74216080
Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administrationQ79370218
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Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junctionQ28215716
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapyQ28255501
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Whole pelvic helical tomotherapy for locally advanced cervical cancer: technical implementation of IMRT with helical tomotherapyQ33387475
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Dose monitoring of 5-fluorouracil in patients with colorectal or head and neck cancer--status of the art.Q33706220
Abdominal irradiation modulates 5-Fluorouracil pharmacokinetics.Q33816059
Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathwayQ34078442
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Radiation-induced hepatitis B virus reactivation in liver mediated by the bystander effect from irradiated endothelial cellsQ40172983
Apical trypsin increases ion transport and resistance by a phospholipase C-dependent rise of Ca2+.Q40475862
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Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumorsQ43054611
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The effect of prednisolone and other factors on the catabolism of 5-fluorouracil in ratsQ44432134
Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: an update of radiation therapy oncology group trial (RTOG) 90-01.Q44780583
Plasma concentrations of 5-fluorouracil and its metabolites in colon cancer patientsQ44921023
5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.Q46616107
Effect of hemodialysis on the metabolic clearance of 5-Fluorouracil in a patient with end-stage renal failureQ46819187
Membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinaseQ47371084
Comparison of radiotherapy strategies for locally advanced hypopharyngeal cancer after resection and ileocolic flap reconstructionQ47588268
Collagenase 2 (MMP-8) expression in murine tissue-remodeling processes. Analysis of its potential role in postpartum involution of the uterusQ48025905
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectfluorouracilQ238512
pharmacokineticsQ323936
P304page(s)e21000
P577publication date2011-01-01
P1433published inPLOS OneQ564954
P1476titleMatrix metalloproteinase-8 mediates the unfavorable systemic impact of local irradiation on pharmacokinetics of anti-cancer drug 5-Fluorouracil
P478volume6