Exploring the Mechanism of Zanamivir Resistance in a Neuraminidase Mutant: A Molecular Dynamics Study

scientific article published on September 6, 2012

Exploring the Mechanism of Zanamivir Resistance in a Neuraminidase Mutant: A Molecular Dynamics Study is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...744057H
P356DOI10.1371/JOURNAL.PONE.0044057
P953full work available at URLhttps://europepmc.org/articles/PMC3435372
https://europepmc.org/articles/PMC3435372?pdf=render
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0044057&type=printable
P932PMC publication ID3435372
P698PubMed publication ID22970161
P5875ResearchGate publication ID230834543

P2093author name stringNanyu Han
Yuguang Mu
Xuewei Liu
P2860cites workAssessing the Accuracy of Metadynamics†Q58465804
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Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivoQ44025966
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Origins of Resistance Conferred by the R292K Neuraminidase Mutation via Molecular Dynamics and Free Energy CalculationsQ51869959
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Escaping free-energy minimaQ34151010
Flexible docking in solution using metadynamicsQ34396573
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectmolecular dynamics simulationQ901663
zanamivirQ146075
viral drug resistanceQ71228770
P304page(s)e44057
P577publication date2012-01-01
2012-09-06
P1433published inPLOS OneQ564954
P1476titleExploring the mechanism of zanamivir resistance in a neuraminidase mutant: a molecular dynamics study
Exploring the Mechanism of Zanamivir Resistance in a Neuraminidase Mutant: A Molecular Dynamics Study
P478volume7

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cites work (P2860)
Q38258646A review of neuraminidase inhibitor susceptibility in influenza strains
Q34057596Characterization of drug-resistant influenza virus A(H1N1) and A(H3N2) variants selected in vitro with laninamivir
Q42273750Design of multiligand inhibitors for the swine flu H1N1 neuraminidase binding site
Q28486224Drug screening for autophagy inhibitors based on the dissociation of Beclin1-Bcl2 complex using BiFC technique and mechanism of eugenol on anti-influenza A virus activity
Q30353814In silico study on multidrug resistance conferred by I223R/H275Y double mutant neuraminidase.
Q30432293Insight into the Oseltamivir Resistance R292K Mutation in H5N1 Influenza Virus: A Molecular Docking and Molecular Dynamics Approach
Q28535754Locking the 150-cavity open: in silico design and verification of influenza neuraminidase inhibitors
Q28486130Plasticity of 150-Loop in Influenza Neuraminidase Explored by Hamiltonian Replica Exchange Molecular Dynamics Simulations
Q35923779Understanding the cross-resistance of oseltamivir to H1N1 and H5N1 influenza A neuraminidase mutations using multidimensional computational analyses

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