New role of JAK2/STAT3 signaling in endothelial cell oxidative stress injury and protective effect of melatonin

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New role of JAK2/STAT3 signaling in endothelial cell oxidative stress injury and protective effect of melatonin is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...857941D
P356DOI10.1371/JOURNAL.PONE.0057941
P3181OpenCitations bibliographic resource ID2250494
P932PMC publication ID3590213
P698PubMed publication ID23483946
P5875ResearchGate publication ID236040248

P50authorWei YiQ43091107
Shiqiang YuQ54637193
P2093author name stringYang Yang
Ning Wang
Yue Li
Dinghua Yi
Juanjuan Yan
Weixun Duan
Wensheng Chen
Zhenxiao Jin
Zhenxin Liang
P2860cites workSignaling through the JAK/STAT pathway, recent advances and future challengesQ28201804
Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytesQ28377588
A potent lead induces apoptosis in pancreatic cancer cellsQ28480566
AG490 prevents cell death after exposure of rat astrocytes to hydrogen peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathwayQ28576489
Exposure of glia to pro-oxidant agents revealed selective Stat1 activation by H2O2 and Jak2-independent antioxidant features of the Jak2 inhibitor AG490Q28583129
Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway.Q34132787
Is red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotectionQ34166155
Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251.Q35230410
A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes.Q36228067
Inhibition of JAK2/STAT3 signalling induces colorectal cancer cell apoptosis via mitochondrial pathwayQ37294261
Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways.Q37430751
Role of melatonin in the regulation of autophagy and mitophagy: a reviewQ38009108
Anti-apoptotic and anti-oxidative mechanisms of minocycline against sphingomyelinase/ceramide neurotoxicity: implication in Alzheimer's disease and cerebral ischemiaQ38009932
Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatoninQ39285748
Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathwayQ39364017
Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cellsQ39382652
Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signalingQ39393886
Dab2 is pivotal for endothelial cell migration by mediating VEGF expression in cancer cellsQ39408655
Melatonin interferes in the desmoplastic reaction in breast cancer by regulating cytokine productionQ39431604
Nickel exposure induces oxidative damage to mitochondrial DNA in Neuro2a cells: the neuroprotective roles of melatoninQ39499163
Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathyQ39658573
Melatonin protects against hydrogen peroxide-induced cell death signaling in SH-SY5Y cultured cells: involvement of nuclear factor kappa B, Bax and Bcl-2.Q40249619
STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cellsQ40264782
Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosisQ41502830
Cytoprotective effects of CSTMP, a novel stilbene derivative, against H2O2-induced oxidative stress in human endothelial cellsQ42721036
Effects of AG490 on lens epithelial cell death induced by H(2)O(2).Q43094459
Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in ratsQ43138989
Melatonin-induced calbindin-D9k expression reduces hydrogen peroxide-mediated cell death in rat pituitary GH3 cellsQ43204868
In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF.Q43823807
Melatonin in cardiovascular disease.Q45998083
Blockade of oxidized LDL-triggered endothelial apoptosis by quercetin and rutin through differential signaling pathways involving JAK2.Q46132088
Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cellsQ46176333
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in ratsQ46231866
ERK MAPK activation mediates the antiapoptotic signaling of melatonin in UVB-stressed U937 cellsQ46309984
Melatonin prevents oxidized low-density lipoprotein-induced increase of myosin light chain kinase activation and expression in HUVEC through ERK/MAPK signal transductionQ46627745
Hyperglycemia and reactive oxygen species mediate apoptosis in aortic endothelial cells through Janus kinase 2.Q46780732
Melatonin and vitamin C ameliorate alcohol-induced oxidative stress and eNOS expression in rat kidneyQ47852608
Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model.Q48676168
Globular adiponectin improves high glucose-suppressed endothelial progenitor cell function through endothelial nitric oxide synthase dependent mechanismsQ48886329
Cytoprotective effects of melatonin on astroglial cells subjected to palmitic acid treatment in vitro.Q50786535
Melatonin inhibits IL-1β-induced monolayer permeability of human umbilical vein endothelial cells via Rac activation.Q52610572
Interleukin-6 autocrine signaling mediates melatonin MT(1/2) receptor-induced STAT3 Tyr(705) phosphorylation.Q53216378
Effects of recombinant human erythropoietin (rhEPO) on JAK2/STAT3 pathway and endothelial apoptosis in the rabbit basilar artery after subarachnoid hemorrhage.Q53423709
[Effects of JAK2/STAT3 signaling pathway on angiogenesis in non-small cell lung cancer].Q54382363
Therapeutic effect of 7, 3'-dimethoxy hesperetin on adjuvant arthritis in rats through inhibiting JAK2-STAT3 signal pathway.Q54497044
The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway.Q54519859
Pain in neonatal intensive care: role of melatonin as an analgesic antioxidantQ62268600
Chronic melatonin consumption prevents obesity-related metabolic abnormalities and protects the heart against myocardial ischemia and reperfusion injury in a prediabetic model of diet-induced obesityQ82440466
Role of the JAK-STAT pathway in protection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cellsQ82880471
Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusionQ83359949
Protective effect of Homer 1a against hydrogen peroxide-induced oxidative stress in PC12 cellsQ83708865
Protective effect of melatonin on liver ischemia-reperfusion induced pulmonary microvascular injury in ratsQ84077720
Effects of melatonin on testis histology, oxidative stress and spermatogenesis after experimental testis ischemia-reperfusion in ratsQ84546559
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
melatoninQ180912
P304page(s)e57941
P577publication date2013-01-01
P1433published inPLOS OneQ564954
P1476titleNew role of JAK2/STAT3 signaling in endothelial cell oxidative stress injury and protective effect of melatonin
P478volume8

Reverse relations

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