Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development

scientific journal article

Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI38922
P3181OpenCitations bibliographic resource ID2142646
P932PMC publication ID2701882
P698PubMed publication ID19509466

P2093author name stringMin Min Lu
Rajan Jain
Jonathan A. Epstein
Klaus H. Kaestner
Kathleen M. Loomes
Warren S. Pear
Frances A. High
Jason Z. Stoller
Nicole B. Antonucci
P2860cites workHesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2Q24294772
Notch signaling in stem cell systemsQ36556388
Origin and fate of cardiac mesenchymeQ37279203
An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heartQ37407385
Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesisQ38498581
PlexinA2 and semaphorin signaling during cardiac neural crest developmentQ40771316
The Outflow Tract of the Heart Is Recruited from a Novel Heart-Forming FieldQ42819988
Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse.Q44132458
Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouseQ45005925
The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart fieldQ46196456
Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic developmentQ46350581
Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell divisionQ47071387
Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouseQ47194311
Right ventricular myocardium derives from the anterior heart fieldQ47290410
Activated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of developmentQ52013182
Conotruncal myocardium arises from a secondary heart fieldQ77102388
The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesodermQ77153201
Jagged1 mutations in patients ascertained with isolated congenital heart defectsQ77356121
Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heartQ77431689
Secondary heart field contributes myocardium and smooth muscle to the arterial pole of the developing heartQ81680192
Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivativesQ81729304
Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynxQ83964348
Mutations in NOTCH1 cause aortic valve diseaseQ24307999
Mutations in the human Jagged1 gene are responsible for Alagille syndromeQ24314702
Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1Q24314766
Slug is a direct Notch target required for initiation of cardiac cushion cellularizationQ24318449
Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heartQ28190508
PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular developmentQ28270667
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversificationQ28275356
Isl1Cre reveals a common Bmp pathway in heart and limb developmentQ28303503
Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rateQ28304688
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineagesQ28306800
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heartQ28507415
Fgf8 is required for anterior heart field developmentQ28511534
Required, tissue-specific roles for Fgf8 in outflow tract formation and remodelingQ28511868
BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardiumQ28586500
Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal developmentQ28587312
The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesisQ28587449
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformationQ28589469
Cardiac outflow tract defects in mice lacking ALK2 in neural crest cellsQ28590197
BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve developmentQ28594976
The incidence of congenital heart diseaseQ29614195
Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesisQ30477732
Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signalingQ30479587
Notch signaling in vascular smooth muscle cells is required to pattern the cerebral vasculatureQ30480288
Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP).Q33823445
Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis.Q33912925
Familial Tetralogy of Fallot caused by mutation in the jagged1 geneQ33930877
Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3Q34014910
An Fgf8 mouse mutant phenocopies human 22q11 deletion syndromeQ34148921
Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signalingQ34524777
Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factorsQ34571556
An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.Q34608845
Notch signaling is an important regulator of type 2 immunity.Q36403646
P4510describes a project that usesImageJQ1659584
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectJagged 1Q21985075
Fibroblast growth factor 8Q21985352
P304page(s)1986–1996
P577publication date2009-07-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleMurine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development
P478volume119

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cites work (P2860)
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