scholarly article | Q13442814 |
P2093 | author name string | Min Min Lu | |
Rajan Jain | |||
Jonathan A. Epstein | |||
Klaus H. Kaestner | |||
Kathleen M. Loomes | |||
Warren S. Pear | |||
Frances A. High | |||
Jason Z. Stoller | |||
Nicole B. Antonucci | |||
P2860 | cites work | Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2 | Q24294772 |
Notch signaling in stem cell systems | Q36556388 | ||
Origin and fate of cardiac mesenchyme | Q37279203 | ||
An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart | Q37407385 | ||
Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis | Q38498581 | ||
PlexinA2 and semaphorin signaling during cardiac neural crest development | Q40771316 | ||
The Outflow Tract of the Heart Is Recruited from a Novel Heart-Forming Field | Q42819988 | ||
Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. | Q44132458 | ||
Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse | Q45005925 | ||
The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field | Q46196456 | ||
Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development | Q46350581 | ||
Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division | Q47071387 | ||
Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse | Q47194311 | ||
Right ventricular myocardium derives from the anterior heart field | Q47290410 | ||
Activated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of development | Q52013182 | ||
Conotruncal myocardium arises from a secondary heart field | Q77102388 | ||
The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm | Q77153201 | ||
Jagged1 mutations in patients ascertained with isolated congenital heart defects | Q77356121 | ||
Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart | Q77431689 | ||
Secondary heart field contributes myocardium and smooth muscle to the arterial pole of the developing heart | Q81680192 | ||
Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives | Q81729304 | ||
Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx | Q83964348 | ||
Mutations in NOTCH1 cause aortic valve disease | Q24307999 | ||
Mutations in the human Jagged1 gene are responsible for Alagille syndrome | Q24314702 | ||
Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1 | Q24314766 | ||
Slug is a direct Notch target required for initiation of cardiac cushion cellularization | Q24318449 | ||
Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart | Q28190508 | ||
PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development | Q28270667 | ||
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification | Q28275356 | ||
Isl1Cre reveals a common Bmp pathway in heart and limb development | Q28303503 | ||
Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rate | Q28304688 | ||
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages | Q28306800 | ||
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart | Q28507415 | ||
Fgf8 is required for anterior heart field development | Q28511534 | ||
Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling | Q28511868 | ||
BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium | Q28586500 | ||
Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development | Q28587312 | ||
The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis | Q28587449 | ||
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation | Q28589469 | ||
Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells | Q28590197 | ||
BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development | Q28594976 | ||
The incidence of congenital heart disease | Q29614195 | ||
Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis | Q30477732 | ||
Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling | Q30479587 | ||
Notch signaling in vascular smooth muscle cells is required to pattern the cerebral vasculature | Q30480288 | ||
Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP). | Q33823445 | ||
Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis. | Q33912925 | ||
Familial Tetralogy of Fallot caused by mutation in the jagged1 gene | Q33930877 | ||
Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3 | Q34014910 | ||
An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome | Q34148921 | ||
Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling | Q34524777 | ||
Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors | Q34571556 | ||
An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation. | Q34608845 | ||
Notch signaling is an important regulator of type 2 immunity. | Q36403646 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Jagged 1 | Q21985075 |
Fibroblast growth factor 8 | Q21985352 | ||
P304 | page(s) | 1986–1996 | |
P577 | publication date | 2009-07-01 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development | |
P478 | volume | 119 |
Q28589314 | A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis |
Q92686567 | A Tie2-Notch1 signaling axis regulates regeneration of the endothelial bone marrow niche |
Q36309299 | Apelin-13 increases myocardial progenitor cells and improves repair postmyocardial infarction |
Q30497723 | Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves |
Q38135363 | Cardiac outflow tract anomalies |
Q38017470 | Cellular decisions in cardiac outflow tract and coronary development: An act by VEGF and NOTCH |
Q34538505 | Common variations in BMP4 confer genetic susceptibility to sporadic congenital heart disease in a Han Chinese population |
Q42768111 | Constitutively active Notch1 signaling promotes endothelial‑mesenchymal transition in a conditional transgenic mouse model |
Q26822995 | Coordinating Tissue Interactions: Notch Signaling in Cardiac Development and Disease |
Q28255041 | Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients |
Q92354322 | Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation |
Q24292921 | Differential Notch Signaling in the Epicardium Is Required for Cardiac Inflow Development and Coronary Vessel Morphogenesis |
Q42322638 | Disheveled mediated planar cell polarity signaling is required in the second heart field lineage for outflow tract morphogenesis |
Q36831801 | Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract |
Q28277874 | Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome |
Q92543211 | Endothelial/Epithelial Mesenchymal Transition in Ascending Aortas of Patients With Bicuspid Aortic Valve |
Q28652450 | Evolutionary and developmental origins of the cardiac neural crest: building a divided outflow tract |
Q36916465 | FRS2α-Mediated FGF Signals Suppress Premature Differentiation of Cardiac Stem Cells Through Regulating Autophagy Activity |
Q39673288 | Fibronectin and integrin alpha 5 play essential roles in the development of the cardiac neural crest |
Q37645871 | Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner |
Q92240511 | Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development |
Q34355325 | Heart fields and cardiac morphogenesis |
Q28513290 | Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome |
Q36283869 | Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development |
Q35576426 | Histone Deacetylase 3 Regulates Smooth Muscle Differentiation in Neural Crest Cells and Development of the Cardiac Outflow Tract |
Q42551402 | Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart |
Q28261364 | Islet1 derivatives in the heart are of both neural crest and second heart field origin |
Q35013321 | Jagged1 is essential for osteoblast development during maxillary ossification |
Q34599920 | Jun Is Required in Isl1-Expressing Progenitor Cells for Cardiovascular Development |
Q35239339 | Loss of Wnt5a disrupts second heart field cell deployment and may contribute to OFT malformations in DiGeorge syndrome |
Q37976513 | Mechanisms of Cardiogenesis in Cardiovascular Progenitor Cells |
Q88970178 | Molecular basis of functional myogenic specification of Bona Fide multipotent adult cardiac stem cells |
Q38320233 | Molecular regulation of cardiomyocyte differentiation |
Q37736652 | Multiple gene variations contributed to congenital heart disease via GATA family transcriptional regulation |
Q47841255 | Mutations in Hnrnpa1 cause congenital heart defects |
Q60924364 | Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function |
Q38045804 | Myocardial regeneration of the failing heart |
Q38570387 | NOTCH1 missense alleles associated with left ventricular outflow tract defects exhibit impaired receptor processing and defective EMT. |
Q36040233 | Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation |
Q35095178 | Nfatc1 Coordinates Valve Endocardial Cell Lineage Development Required for Heart Valve Formation |
Q34541286 | Notch Signaling in Descending Thoracic Aortic Aneurysm and Dissection |
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Q35946564 | Notch signaling and cardiac repair |
Q49262687 | Notch1 haploinsufficiency causes ascending aortic aneurysms in mice |
Q36108192 | Numb family proteins: novel players in cardiac morphogenesis and cardiac progenitor cell differentiation |
Q33655265 | Outflow tract septation and the aortic arch system in reptiles: lessons for understanding the mammalian heart. |
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Q35904479 | Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure |
Q36877617 | Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development. |
Q38269616 | Review of molecular and mechanical interactions in the aortic valve and aorta: implications for the shared pathogenesis of aortic valve disease and aortopathy |
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