A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes

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A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes is …
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scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.23-32-10214.2003
P932PMC publication ID6741010
P698PubMed publication ID14614079

P50authorThomas J. HudsonQ3525236
Reza ForghaniQ38801565
P2093author name stringLuc Jasmin
Webb Miller
Alan C Peterson
Pierre Lepage
Wayel Orfali
Hana C H Friedman
Hooman F Farhadi
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
The DNA sequence and comparative analysis of human chromosome 20Q21735926
Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence ComparisonsQ22065547
The Sequence of the Human GenomeQ22065842
Genomic cis-regulatory logic: experimental and computational analysis of a sea urchin geneQ46041940
Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respirationQ46300253
Cis-regulatory logic in the endo16 gene: switching from a specification to a differentiation mode of control.Q46537128
Structure and developmental regulation of Golli-mbp, a 105-kilobase gene that encompasses the myelin basic protein gene and is expressed in cells in the oligodendrocyte lineage in the brainQ48129601
The proximal region of the MBP gene promoter is sufficient to induce oligodendroglial-specific expression in transgenic mice.Q48281761
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genomeQ48300754
Myelin acquisition in the central nervous system of the mouse revealed by an MBP-Lac Z transgeneQ48405146
Cell and tissue-specific expression of a heterologous gene under control of the myelin basic protein gene promoter in transgenic miceQ48526756
A minimal human MBP promoter-lacZ transgene is appropriately regulated in developing brain and after optic enucleation, but not in shiverer mutant miceQ48531575
Dysmyelination in transgenic mice resulting from expression of class I histocompatibility molecules in oligodendrocytesQ48640177
The specificity of the myelin basic protein gene promoter studied in transgenic miceQ48723405
Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves.Q52118842
A distal upstream enhancer from the myelin basic protein gene regulates expression in myelin-forming schwann cells.Q52135105
Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice.Q52175781
P0 promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice.Q52232541
Long Human–Mouse Sequence Alignments Reveal Novel Regulatory Elements: A Reason to Sequence the Mouse GenomeQ63433341
Hypomyelination in the peripheral nervous system of shiverer mice and inShiverer ?Normal chimaeraQ72745839
Linkage disequilibrium between the MBP tetranucleotide repeat and multiple sclerosis is restricted to a geographically defined subpopulation in FinlandQ73083005
Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombinationQ73334400
The re-expression of the homeodomain transcription factor Gtx during remyelination of experimentally induced demyelinating lesions in young and old rat brainQ74341544
Initial sequencing and comparative analysis of the mouse genomeQ22122521
An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencingQ24291759
Analysis of vertebrate SCL loci identifies conserved enhancersQ28143951
Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10Q28511593
PipMaker--a web server for aligning two genomic DNA sequencesQ28776457
Xist yeast artificial chromosome transgenes function as X-inactivation centers only in multicopy arrays and not as single copiesQ33957815
Why does remyelination fail in multiple sclerosis?Q34147437
The TRANSFAC system on gene expression regulation.Q34304310
Krox-20 controls myelination in the peripheral nervous systemQ34324119
Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domainsQ34422276
Endogenous progenitors remyelinate demyelinated axons in the adult CNS.Q34434566
Modeling DNA sequence-based cis-regulatory gene networksQ34654776
Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the diseaseQ35057231
A myelin proteolipid protein-LacZ fusion protein is developmentally regulated and targeted to the myelin membrane in transgenic miceQ36233433
Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expressionQ36532104
Identification of an embryonic isoform of myelin basic protein that is expressed widely in the mouse embryoQ36634942
Transgenic mouse model for central nervous system demyelinationQ36747079
Single-copy transgenic mice with chosen-site integrationQ37384432
The transcription factor Sox10 is a key regulator of peripheral glial development.Q40423560
Gtx, an oligodendrocyte-specific homeodomain protein, has repressor activityQ40863557
Local recruitment of remyelinating cells in the repair of demyelination in the central nervous systemQ41066214
Evidence that the homeodomain protein Gtx is involved in the regulation of oligodendrocyte myelinationQ42425834
Four-kilobase sequence of the mouse CNP gene directs spatial and temporal expression of lacZ in transgenic miceQ42460062
Expression of a myelin basic protein gene in transgenic shiverer mice: correction of the dysmyelinating phenotype.Q44381714
Schwann cells are removed from the spinal cord after effecting recovery from paraplegia.Q44489549
The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.Q46021705
P4510describes a project that usesImageQuantQ112270642
P433issue32
P407language of work or nameEnglishQ1860
P921main subjectMyelin basic proteinQ14876145
P304page(s)10214-10223
P577publication date2003-11-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleA combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes
P478volume23

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cites work (P2860)
Q92296537A principled strategy for mapping enhancers to genes
Q34151669A regulatory toolbox of MiniPromoters to drive selective expression in the brain
Q28256953A tale of two citrullines--structural and functional aspects of myelin basic protein deimination in health and disease
Q36560563Artificial chromosome-based transgenes in the study of genome function
Q83828090Axonal degeneration stimulates the formation of NG2+ cells and oligodendrocytes in the mouse
Q28505601CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure
Q24656272Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences
Q46261532Characterization of the regulatory region of the dopa decarboxylase gene in Medaka: an in vivo green fluorescent protein reporter assay combined with a simple TA-cloning method
Q58091778Corticohippocampal Dysfunction In The OBiden Mouse Model Of Primary Oligodendrogliopathy
Q36279083Differential Sox10 genomic occupancy in myelinating glia
Q33707460Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells
Q52032792Functional organization of a Schwann cell enhancer.
Q38441469Functional organization of an Mbp enhancer exposes striking transcriptional regulatory diversity within myelinating glia
Q61065665Generation of mice with conditionally activated transforming growth factor beta signaling through the TβRI/ALK5 receptor
Q37032402Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy
Q40173356Hypo-osmolar stress induces p75NTR expression by activating Sp1-dependent transcription.
Q55346781In Vivo Optical Imaging of Myelination Events in a Myelin Basic Protein Promoter-Driven Luciferase Transgenic Mouse Model.
Q43994351Induction of experimental autoimmune encephalomyelitis in transgenic mice expressing ovalbumin in oligodendrocytes
Q38735100Inflammation and remyelination in the central nervous system: a tale of two systems
Q37263985Integrin-mediated axoglial interactions initiate myelination in the central nervous system
Q36832884Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS.
Q58836375Multicolor analysis of oligodendrocyte morphology, interactions, and development with Brainbow
Q34388928Multiple transcripts of sodium channel SCN8A (Na(V)1.6) with alternative 5'- and 3'-untranslated regions and initial characterization of the SCN8A promoter
Q34699724Neural stem cell differentiation is dictated by distinct actions of nuclear receptor corepressors and histone deacetylases
Q43535949Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus.
Q33588592Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice
Q39642235Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer
Q30483578PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation
Q42228859Phosphodiesterase-5 is a therapeutic target for peripheral neuropathy in diabetic mice
Q36753717Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination.
Q35950121Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system.
Q34779364Regulatory modules function in a non-autonomous manner to control transcription of the mbp gene.
Q41994444Schwann cell myelination requires Dynein function
Q46506127Separate proteolipid protein/DM20 enhancers serve different lineages and stages of development
Q43194991Spatial monitoring of toxicity in HMOX-LacZ transgenic mice.
Q37711706Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.
Q36569224Targeted deletion of the antisilencer/enhancer (ASE) element from intron 1 of the myelin proteolipid protein gene (Plp1) in mouse reveals that the element is dispensable for Plp1 expression in brain during development and remyelination
Q49033569Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation
Q46658617Temporally controlled prostate epithelium-specific gene alterations
Q34092185The molecular machinery of myelin gene transcription in Schwann cells
Q32874749The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes
Q35259052Towards resolving the transcription factor network controlling myelin gene expression
Q63616086Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele
Q50709614Ubiquitous expression of mRFP-1 in vivo by site-directed transgenesis.
Q29029045Use of Transgenic Animals to Improve Human Health and Animal Production
Q37815869When needles look like hay: how to find tissue-specific enhancers in model organism genomes

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