Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud

scientific journal article

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/DVDY.20590
P8608Fatcat IDrelease_4kjzbj357batxh425pypn3lnqi
P698PubMed publication ID16245338
P5875ResearchGate publication ID7521971

P50authorFreddy RadtkeQ41621239
P2093author name stringFreddy Radtke
Jeffrey C. Francis
Malcolm P. O. Logan
P2860cites workFunctions of FGF signalling from the apical ectodermal ridge in limb developmentQ28216618
Notch signaling: control of cell communication and cell fateQ28245948
Inducible gene targeting in mice using the Cre/lox systemQ28272460
The roles of FGFs in the early development of vertebrate limbsQ28273288
Essential role of endothelial Notch1 in angiogenesisQ28509482
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of splitQ28577019
Defects in limb, craniofacial, and thymic development in Jagged2 mutant miceQ28586431
Tbx5 is required for forelimb bud formation and continued outgrowthQ28591196
Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathwayQ28592687
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6Q28593218
Regulation of notch signaling activityQ28610136
Sonic hedgehog mediates the polarizing activity of the ZPAQ29616565
HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesisQ30176413
The distribution of Notch receptors and their ligands during articular cartilage developmentQ30959291
Arbiter of differentiation and death: Notch signaling meets apoptosisQ33755151
Suppression of differentiation and proliferation of early chondrogenic cells by NotchQ34273421
Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signalingQ34391655
Notch signaling in vascular developmentQ35077358
Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryosQ35198324
Preovulatory treatment of mice with anti-VEGF receptor 2 antibody inhibits angiogenesis in corpora luteaQ38299598
Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesisQ38327383
A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesisQ38360357
Serrate2 is disrupted in the mouse limb-development mutant syndactylismQ39454683
Control of skeletal patterning by ephrinB1-EphB interactionsQ39657563
Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1.Q40488277
Cell cycle arrest and apoptosis induced by Notch1 in B cellsQ40857740
Notch 1 impairs osteoblastic cell differentiationQ42796277
Consequences of Notch-mediated induction of Jagged1.Q42828884
A role for hairy1 in regulating chick limb bud growthQ43814674
Cortisol regulates the expression of Notch in osteoblastsQ43956288
Deficient T cell fate specification in mice with an induced inactivation of Notch1.Q45345200
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.Q45345845
Function of BMPs in the apical ectoderm of the developing mouse limbQ47774270
Abdominal B (AbdB) Hoxa genes: regulation in adult uterus by estrogen and progesterone and repression in müllerian duct by the synthetic estrogen diethylstilbestrol (DES).Q47961660
In vivo inhibition of programmed cell death by local administration of FGF-2 and FGF-4 in the interdigital areas of the embryonic chick leg bud.Q50539128
Fgf signaling controls the number of phalanges and tip formation in developing digits.Q52099058
Expression patterns of Notch1, Serrate1, Serrate2 and Delta1 in tissues of the developing chick limb.Q52182018
Fringe modulates Notch-ligand interactions.Q52194027
Complementary and combinatorial patterns of Notch gene family expression during early mouse development.Q52204884
Notch1 is essential for postimplantation development in mice.Q52512097
Short-range cell interactions and cell survival in the Drosophila wing.Q52596954
Morphological Diversity of the Avian Foot Is Related with the Pattern ofmsxGene Expression in the Developing AutopodQ60355824
Stimulation of osteoblastic cell differentiation by NotchQ64379236
Expression of Cre recombinase in the developing mouse limb bud driven by aPrxl enhancerQ64965676
Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic developmentQ69123971
Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plateQ70732933
Characterisation of hoxa gene expression in the chick limb bud in response to FGFQ73367369
Antagonistic effects of FGF4 on BMP induction of apoptosis and chondrogenesis in the chick limb budQ74326349
Bmp4 in limb bud mesoderm regulates digit pattern by controlling AER developmentQ81101395
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
Apical ectodermal ridgeQ4779801
Notch 1Q21986193
P304page(s)1006–1015
P577publication date2005-12-01
P1433published inDevelopmental DynamicsQ59752
P1476titleNotch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud
P478volume234

Reverse relations

cites work (P2860)
Q42157352BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation
Q39764124Birth and death of cells in limb development: a mapping study.
Q93140380Curcumin attenuates hypoxia/reoxygenation‑induced cardiomyocyte injury by downregulating Notch signaling
Q36319792Different regulation of limb development by p63 transcript variants
Q45399454Dimeric combinations of MafB, cFos and cJun control the apoptosis-survival balance in limb morphogenesis
Q31152378Elucidating the genetic basis of an oligogenic birth defect using whole genome sequence data in a non-model organism, Bubalus bubalis
Q40114200Formation of normal interdigital web spaces in the hand revisited: implications for the pathogenesis of syndactyly in humans and experimental animals
Q51795277Generation and characterization of a Notch1 signaling-specific reporter mouse line.
Q21145242Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
Q33589613Genetic control of programmed cell death during animal development
Q38848655Hajdu-Cheney Syndrome, a Disease Associated with NOTCH2 Mutations
Q34728226Hajdu-Cheney syndrome: a review
Q28261852Haploinsufficiency of the NOTCH1 Receptor as a Cause of Adams-Oliver Syndrome With Variable Cardiac Anomalies
Q37505652Notch signaling in chondrogenesis
Q35848797Notch signaling in skeletal health and disease
Q34808308Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish
Q33786247RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
Q33830606Senescence gives insights into the morphogenetic evolution of anamniotes.
Q38116930The molecular basis of human congenital limb malformations

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