Augmenting endogenous Wnt signaling improves skin wound healing

scientific article (publication date: 2013)

Augmenting endogenous Wnt signaling improves skin wound healing is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...876883W
P356DOI10.1371/JOURNAL.PONE.0076883
P932PMC publication ID3799989
P698PubMed publication ID24204695
P5875ResearchGate publication ID258350762

P50authorNicholas D EvansQ56445859
P2093author name stringBo Liu
Howard Y Chang
Andrew A Smith
Jill A Helms
Girija R Dhamdhere
Mark Y Fang
Jemima L Whyte
Anthony E Oro
Wilfred R Manzano
P2860cites workFibroblasts, myofibroblasts, and wound contractionQ24673630
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Skin regeneration in adult axolotls: a blueprint for scar-free healing in vertebratesQ27307724
A common human skin tumour is caused by activating mutations in beta-cateninQ28115245
Hair cycle regulation of Hedgehog signal receptionQ28185267
The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesisQ28207636
Retinoic acid signaling is required during early chick limb development.Q52201912
Hair and wound healing: anagen gets an "A".Q53275733
Safe harbours for the integration of new DNA in the human genomeQ57008552
Skin, heal thyselfQ59292535
Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the SkinQ63406949
Excisional wound biomechanics, skin tension lines, and elastic contractionQ67552338
Apoptosis is increased in a model of diabetes-impaired wound healing in genetically diabetic miceQ73169451
Epidermal stem cells arise from the hair follicle after woundingQ79666857
Cellular senescence mechanisms in chronic wound healingQ81699208
The role of R-spondin2 in keratinocyte proliferation and epidermal thickening in keloid scarringQ82901140
Skin shedding and tissue regeneration in African spiny mice (Acomys)Q28275914
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3betaQ28505773
NFATc1 balances quiescence and proliferation of skin stem cellsQ28511548
Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartmentsQ28590882
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiationQ28591262
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epitheliaQ28591794
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathwayQ28640887
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumorsQ28640916
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell nicheQ29614984
Defining the epithelial stem cell niche in skinQ29614985
Wound healing--aiming for perfect skin regenerationQ29616715
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumorsQ29619814
Involvement of Wnt signaling in dermal fibroblastsQ33597125
Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair.Q33999191
Wnt-dependent de novo hair follicle regeneration in adult mouse skin after woundingQ34629066
Cyclic dermal BMP signalling regulates stem cell activation during hair regenerationQ34737529
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.Q35079614
Wnt signaling maintains the hair-inducing activity of the dermal papillaQ35193923
Craniosynostosis caused by Axin2 deficiency is mediated through distinct functions of beta-catenin in proliferation and differentiationQ35677733
Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skinQ35793451
Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiationQ35841035
New insights into craniofacial morphogenesisQ36037960
Distinct Wnt signaling pathways have opposing roles in appendage regenerationQ38507574
Wnt proteins promote bone regenerationQ39709638
Scarless wound healing: implications for the aesthetic surgeon.Q40478496
An extended epidermal response heals cutaneous wounds in the absence of a hair follicle stem cell contribution.Q42820170
Exploring the "hair growth-wound healing connection": anagen phase promotes wound re-epithelializationQ43407107
Exogenous Smad3 accelerates wound healing in a rabbit dermal ulcer modelQ44436892
A zone of frontonasal ectoderm regulates patterning and growth in the face.Q45999105
Controlling the in vivo activity of Wnt liposomes.Q46163007
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumoursQ47764649
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectwound healingQ1509074
P304page(s)e76883
P577publication date2013-10-18
P1433published inPLOS OneQ564954
P1476titleAugmenting endogenous Wnt signaling improves skin wound healing
P478volume8

Reverse relations

cites work (P2860)
Q35105698A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cells
Q33730074Adipose-derived stem cells cooperate with fractional carbon dioxide laser in antagonizing photoaging: a potential role of Wnt and β-catenin signaling
Q40888327An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function
Q36009506Differentially expressed miRNAs in acute wound healing of the skin: a pilot study
Q33787188Elevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signaling
Q36299831Inhibition of Wnt/β-catenin pathway promotes regenerative repair of cutaneous and cartilage injury.
Q43599075Keloid-derived, plasma/fibrin-based skin equivalents generate de novo dermal and epidermal pathology of keloid fibrosis in a mouse model
Q39100891Minimizing Skin Scarring through Biomaterial Design
Q38570923Nanomaterials for wound healing: scope and advancement
Q36244482Neotenic phenomenon in gene expression in the skin of Foxn1- deficient (nude) mice - a projection for regenerative skin wound healing
Q50448386PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations
Q26823939Palatogenesis and cutaneous repair: A two-headed coin
Q37152121Rescuing failed oral implants via Wnt activation
Q47561285Scarless wound healing: Transitioning from fetal research to regenerative healing
Q47701333Skin and Its Regenerative Powers: An Alliance between Stem Cells and Their Niche
Q26748513Stem Cells in Skin Wound Healing: Are We There Yet?
Q48142989Stromal Gli2 activity coordinates a niche signaling program for mammary epithelial stem cells.
Q26821978Targeting the Wnt pathways for therapies
Q33736914Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2.
Q35824206The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing
Q92139929Tissue engineering strategies combining molecular targets against inflammation and fibrosis, and umbilical cord blood stem cells to improve hampered muscle and skin regeneration following cleft repair
Q41628458Wnt Acts as a Prosurvival Signal to Enhance Dentin Regeneration.
Q38569131Wnt Signaling and Its Contribution to Craniofacial Tissue Homeostasis.
Q26797262Wnt signaling induces epithelial differentiation during cutaneous wound healing
Q64954038β-Catenin-Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding.

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