Force transduction and lipid binding in MscL: a continuum-molecular approach

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Force transduction and lipid binding in MscL: a continuum-molecular approach is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9k3947V
P356DOI10.1371/JOURNAL.PONE.0113947
P3181OpenCitations bibliographic resource ID577951
P932PMC publication ID4250078
P698PubMed publication ID25437007
P5875ResearchGate publication ID269095633

P2093author name stringMarino Arroyo
Juan M Vanegas
P2860cites work3D pressure field in lipid membranes and membrane-protein complexes.Q51788823
An improved united atom force field for simulation of mixed lipid bilayers.Q51798189
Molecular dissection of the large mechanosensitive ion channel (MscL) of E. coli: mutants with altered channel gating and pressure sensitivity.Q54567112
Definition and testing of the GROMOS force-field versions 54A7 and 54B7Q56225271
CHARMM-GUI: a web-based graphical user interface for CHARMMQ80900573
Lipid-protein interactionsQ84157392
The determinants of hydrophobic mismatch response for transmembrane helicesQ85004924
Importance of Force Decomposition for Local Stress Calculations in Biomembrane Molecular SimulationsQ86720961
Crystal structure of the human two-pore domain potassium channel K2P1Q24303649
Membrane-protein interactions in mechanosensitive channelsQ24538186
Revisiting hydrophobic mismatch with free energy simulation studies of transmembrane helix tilt and rotationQ24623070
Mechanosensitive channels: what can they do and how do they do it?Q24633554
Analytic models for mechanotransduction: gating a mechanosensitive channelQ24633961
CHARMM: the biomolecular simulation programQ24658108
Hierarchies, multiple energy barriers, and robustness govern the fracture mechanics of alpha-helical and beta-sheet protein domainsQ24678577
Crystal structure of rhodopsin: A G protein-coupled receptorQ27625972
Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective AntagonistQ27666030
Structural Basis for Molecular Recognition at Serotonin ReceptorsQ27676926
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular SimulationQ27860944
Generation and evaluation of a large mutational library from the Escherichia coli mechanosensitive channel of large conductance, MscL: implications for channel gating and evolutionary designQ28188123
The gating mechanism of the large mechanosensitive channel MscLQ28202124
Structural models of the MscL gating mechanismQ28207726
Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gatingQ28217366
Loss-of-function mutations at the rim of the funnel of mechanosensitive channel MscLQ28252469
Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channelQ28291702
Single residue substitutions that change the gating properties of a mechanosensitive channel in Escherichia coliQ28293902
Structure and mechanism in prokaryotic mechanosensitive channelsQ30311180
Energetics of hydrogen bonds in peptides.Q30336189
Gating of the mechanosensitive channel protein MscL: the interplay of membrane and proteinQ30367265
g_membed: Efficient insertion of a membrane protein into an equilibrated lipid bilayer with minimal perturbationQ30387289
Membrane proteins diffuse as dynamic complexes with lipids.Q30389145
The gating mechanism of the bacterial mechanosensitive channel MscL revealed by molecular dynamics simulations: from tension sensing to channel openingQ30423526
Water clusters: untangling the mysteries of the liquid, one molecule at a timeQ31964801
Hydrophobic mismatch of mobile transmembrane helices: Merging theory and experimentsQ33353021
VORO++: a three-dimensional voronoi cell library in C++.Q33522732
Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK.Q33896398
Release of content through mechano-sensitive gates in pressurized liposomesQ34147450
An improved open-channel structure of MscL determined from FRET confocal microscopy and simulationQ34161460
Gating of MscL Studied by Steered Molecular DynamicsQ34182988
Probing the relation between force--lifetime--and chemistry in single molecular bondsQ34243206
Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniquesQ34624392
Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes.Q35606672
Three routes to modulate the pore size of the MscL channel/nanovalveQ35788552
Sensing and responding to membrane tension: the bacterial MscL channel as a model system.Q36105316
Membrane mechanics as a probe of ion-channel gating mechanisms.Q36395029
Three-dimensional stress field around a membrane protein: atomistic and coarse-grained simulation analysis of gramicidin A.Q36518513
Chimeras reveal a single lipid-interface residue that controls MscL channel kinetics as well as mechanosensitivityQ36673509
On the structure of the N-terminal domain of the MscL channel: helical bundle or membrane interfaceQ36838841
Dynamics of protein-protein interactions at the MscL periplasmic-lipid interfaceQ37533546
Assessment of potential stimuli for mechano-dependent gating of MscL: effects of pressure, tension, and lipid headgroupsQ39362425
Interactions of phospholipids with the potassium channel KcsA.Q40215125
Modulation of rhodopsin function by properties of the membrane bilayerQ40655644
Different effects of lipid chain length on the two sides of a membrane and the lipid annulus of MscL.Q42592729
Contributions of the different extramembranous domains of the mechanosensitive ion channel MscL to its response to membrane tension.Q42616686
Anionic phospholipids affect the rate and extent of flux through the mechanosensitive channel of large conductance MscL.Q43202528
Mechanosensitive ion channels of E. coli activated by amphipaths.Q45044862
Hydration properties of mechanosensitive channel pores define the energetics of gatingQ47319724
Opposite modulation of NMDA receptors by lysophospholipids and arachidonic acid: common features with mechanosensitivityQ48355564
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)e113947
P577publication date2014-01-01
P1433published inPLOS OneQ564954
P1476titleForce transduction and lipid binding in MscL: a continuum-molecular approach
P478volume9

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cites work (P2860)
Q90640032Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets
Q53122328Channel disassembled: Pick, tweak, and soak parts to soften.
Q64245550Computational Modeling of Realistic Cell Membranes
Q38725688Continuum descriptions of membranes and their interaction with proteins: Towards chemically accurate models.
Q38928950From membrane tension to channel gating: A principal energy transfer mechanism for mechanosensitive channels
Q51420842Gating mechanism of mechanosensitive channel of large conductance: a coupled continuum mechanical-continuum solvation approach.
Q35961203Gating of a mechanosensitive channel due to cellular flows
Q37690319High-Throughput Simulations Reveal Membrane-Mediated Effects of Alcohols on MscL Gating.
Q26798390Molecular Simulations of Gram-Negative Bacterial Membranes: A Vignette of Some Recent Successes
Q63547192Multiscale Simulations of Biological Membranes: The Challenge To Understand Biological Phenomena in a Living Substance
Q53717221Nonuniqueness of local stress of three-body potentials in molecular simulations.
Q41577849Pulling MscL open via N-terminal and TM1 helices: A computational study towards engineering an MscL nanovalve
Q59801457Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2
Q35950796The Combined Effect of Hydrophobic Mismatch and Bilayer Local Bending on the Regulation of Mechanosensitive Ion Channels
Q92732450The plasma membrane as a mechanochemical transducer
Q27342278The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels

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