A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis

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A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9j7182R
P356DOI10.1371/JOURNAL.PONE.0107182
P3181OpenCitations bibliographic resource ID2202001
P932PMC publication ID4169656
P698PubMed publication ID25238069
P5875ResearchGate publication ID265859541

P2093author name stringBasappa
Kanchugarakoppal S Rangappa
Kesturu S Girish
Swamy Jagadish
Mahalingam S Sundaram
Kempaiah Kemparaju
Manoj Paul
Chakrabhavi D Mohan
Toreshettahally R Swaroop
Mahadevappa Hemshekhar
Ajjampura C Vinayaka
Marilinganadoddi P Sadashiva
Ram M Thushara
Kodagahalli S Rakesh
P2860cites workSelective triggering of platelet apoptosis, platelet activation or both.Q53120716
Thrombin induces apoptotic events through the generation of reactive oxygen species in human platelets.Q53546960
Cinnamtannin B-1 from bay wood exhibits antiapoptotic effects in human plateletsQ62090059
Antioxidant actions of du-zhong (Eucommia ulmoides Oliv.) toward oxidative damage in biomoleculesQ73518074
HPLC method for evaluation of the free radical-scavenging activity of foods by using 1,1-diphenyl-2-picrylhydrazylQ74841762
Advances in antiplatelet therapyQ79353188
Early caspase-3 activation independent of apoptosis is required for cellular functionQ79769437
Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulationQ85197039
The metalloprotease, NN-PF3 from Naja naja venom inhibits platelet aggregation primarily by affecting α2β1 integrinQ85216603
Influence of platelet γ-glutamyltransferase on oxidative stress and apoptosis in the presence of holo-transferrinQ85720759
Aspirin Induces platelet apoptosisQ85860682
Crocin, a dietary additive protects platelets from oxidative stress-induced apoptosis and inhibits platelet aggregationQ87442820
Protein measurement with the Folin phenol reagentQ20900776
Blood platelets in the progression of Alzheimer's diseaseQ27318080
A systematic evaluation of laboratory testing for drug-induced immune thrombocytopeniaQ27686838
Aspirin induces platelet receptor shedding via ADAM17 (TACE)Q28192102
Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDsQ33354062
Immunological HCV-associated thrombocytopenia: short reviewQ33402517
Pathophysiology and management of primary immune thrombocytopeniaQ33407942
Melatonin elevates apoptosis in human platelets via ROS mediated mitochondrial damageQ33409295
Therapeutic drug-induced platelet apoptosis: an overlooked issue in pharmacotoxicologyQ33412254
Nonalcoholic fatty liver disease may cause thrombocytopeniaQ33413578
Redox control of platelet functions in physiology and pathophysiologyQ33413673
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's diseaseQ34306241
Fever management: evaluating the use of ibuprofen and paracetamolQ34619145
Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis.Q37127450
Aldose reductase-mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic plateletsQ37707000
Apoptosis in the anucleate plateletQ37953023
Ibuprofen: from invention to an OTC therapeutic mainstayQ38060825
Differential action of phytochemicals on platelet apoptosis: a biological overviewQ38064940
Pharmacogenomics of anti-platelet and anti-coagulation therapyQ38116753
Membrane microparticles and diseasesQ38148733
Mitochondria: biological roles in platelet physiology and pathology.Q38191094
Usefulness of selective COX-2 inhibitors as therapeutic agents against canine mammary tumorsQ39026414
Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70.Q39028807
Mitochondrial analysis in living cells: the use of rhodamine 123 and flow cytometryQ39479961
Genipin suppresses A23187-induced cytotoxicity in neuro2a cellsQ39844818
Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxisQ41570554
A colorimetric method for the measurement of platelet adhesion in microtiter platesQ42285656
Severe platelet desialylation in a patient with glycoprotein Ib/IX antibody-mediated immune thrombocytopenia and fatal pulmonary hemorrhageQ42385045
Dual role of the p38 MAPK/cPLA2 pathway in the regulation of platelet apoptosis induced by ABT-737 and strong platelet agonistsQ42854205
Mean platelet volume in patients with obstructive sleep apnea syndrome and its relationship with cardiovascular diseasesQ43769079
Mean platelet volume is associated with glycaemic control and retinopathy in patients with type 2 diabetes mellitusQ44068825
Drug/drug interaction of common NSAIDs with antiplatelet effect of aspirin in human plateletsQ44648420
Thrombin-induced caspases 3 and 9 translocation to the cytoskeleton is independent of changes in cytosolic calcium in human platelets.Q46437817
Misinterpretation of the effect of amlodipine on cytosolic calcium concentration with fura-2 fluorospectrometryQ46785761
Assay for apoptosis using the mitochondrial probes, Rhodamine123 and 10-N-nonyl acridine orangeQ46850584
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectplatelet aggregationQ14913634
P304page(s)e107182
P577publication date2014-01-01
P1433published inPLOS OneQ564954
P1476titleA new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis
P478volume9

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