3-Dimensional culture systems for anti-cancer compound profiling and high-throughput screening reveal increases in EGFR inhibitor-mediated cytotoxicity compared to monolayer culture systems

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3-Dimensional culture systems for anti-cancer compound profiling and high-throughput screening reveal increases in EGFR inhibitor-mediated cytotoxicity compared to monolayer culture systems is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9j8283H
P356DOI10.1371/JOURNAL.PONE.0108283
P3181OpenCitations bibliographic resource ID4346292
P932PMC publication ID4172726
P698PubMed publication ID25247711
P5875ResearchGate publication ID265970538

P2093author name stringKristiina Vuori
Darren Finlay
Robyn D Richardson
Amy L Howes
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HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironmentQ34111958
High-throughput 3D spheroid culture and drug testing using a 384 hanging drop arrayQ34145183
The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancerQ34291977
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Modeling tissue morphogenesis and cancer in 3D.Q34667330
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Three-dimensional tissue culture models in cancer biologyQ36173561
Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cellsQ37456176
Small-molecule inhibitors of the human epidermal receptor family.Q37638679
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcytotoxicityQ246181
high-throughput screeningQ626251
P304page(s)e108283
P577publication date2014-01-01
P1433published inPLOS OneQ564954
P1476title3-Dimensional culture systems for anti-cancer compound profiling and high-throughput screening reveal increases in EGFR inhibitor-mediated cytotoxicity compared to monolayer culture systems
P478volume9

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