A significant reduction in the frequency of HIV-1 drug resistance in Québec from 2001 to 2011 is associated with a decrease in the monitored viral load

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A significant reduction in the frequency of HIV-1 drug resistance in Québec from 2001 to 2011 is associated with a decrease in the monitored viral load is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9j9420C
P356DOI10.1371/JOURNAL.PONE.0109420
P932PMC publication ID4190276
P698PubMed publication ID25295725
P5875ResearchGate publication ID266626278

P50authorMark WainbergQ3294273
Michel RogerQ57303410
Bluma BrennerQ60299886
Hugues CharestQ86870110
Cécile TremblayQ88627432
Daniela MoisiQ115623576
Jean-Guy BarilQ121183517
Isabelle HardyQ122902540
P2093author name stringDonald G Murphy
Ernest Lo
Florence Doualla-Bell
Linda Lemieux
Régis Cantin
P2860cites workPrevalence of HIV-1 drug resistance in treated patients: a French nationwide study.Q51914235
Low level of the K103N HIV-1 above a threshold is associated with virological failure in treatment-naive individuals undergoing efavirenz-containing therapy.Q54397378
Reduced emergence of the M184V/I resistance mutation when antiretroviral-naïve subjects use emtricitabine versus lamivudine in regimens composed of two NRTIs plus the NNRTI efavirenz.Q54596202
Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studiesQ24597052
Prevention of HIV-1 infection with early antiretroviral therapyQ24634688
Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009Q28476489
Sentinel surveillance of HIV-1 transmitted drug resistance, acute infection and recent infectionQ28477399
Recent HIV-1 infection contributes to the viral diffusion over the French territory with a recent increasing frequencyQ28480667
Low prevalence of transmitted drug resistance in patients newly diagnosed with HIV-1 infection in Sweden 2003-2010Q28481603
Impact of low-level-viremia on HIV-1 drug-resistance evolution among antiretroviral treated-patientsQ28483630
Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study GroupQ29614934
Brief but efficient: acute HIV infection and the sexual transmission of HIV.Q30341429
Decreases in community viral load are accompanied by reductions in new HIV infections in San FranciscoQ33604727
Treatment to prevent transmission of HIV-1Q34102424
Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based studyQ34126545
Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapineQ35021860
A Guide to HIV-1 Reverse Transcriptase and Protease Sequencing for Drug Resistance StudiesQ35742512
Prevalence of transmitted antiretroviral drug resistance differs between acutely and chronically HIV-infected patientsQ36279238
Transmission networks of drug resistance acquired in primary/early stage HIV infectionQ37115372
Longitudinal community plasma HIV-1 RNA concentrations and incidence of HIV-1 among injecting drug users: prospective cohort study.Q37175647
Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: a systematic review and meta-analysisQ37531320
Preventing HIV transmission through antiretroviral treatment-mediated virologic suppression: aspects of an emerging scientific agendaQ37974036
Temporal changes in the epidemiology of transmission of drug-resistant HIV-1 across the world.Q37980615
The prevalence of antiretroviral drug resistance in the United StatesQ39687529
High rates of forward transmission events after acute/early HIV-1 infectionQ39788342
The impact of transmission clusters on primary drug resistance in newly diagnosed HIV-1 infectionQ39887453
Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical managementQ40396257
Different evolution of genotypic resistance profiles to emtricitabine versus lamivudine in tenofovir-containing regimensQ42925586
Trends in transmitted drug-resistant HIV-1 and demographic characteristics of newly diagnosed patients: Nationwide surveillance from 2003 to 2008 in JapanQ44103745
Decline in deaths from AIDS due to new antiretroviralsQ44184848
Transmission of drug-resistant HIV-1 is stabilizing in EuropeQ44591236
Long-term trends of HIV type 1 drug resistance prevalence among antiretroviral treatment-experienced patients in SwitzerlandQ45069480
Transmission network of an HIV type 1 strain with K103N in young Belgian patients from different risk groupsQ45114115
In vivo dynamics of the K103N mutation following the withdrawal of non-nucleoside reverse transcriptase inhibitors in Human Immunodeficiency Virus-infected patientsQ45421198
Resistance profiles of emtricitabine and lamivudine in tenofovir-containing regimensQ45811702
Antiretroviral-drug resistance among patients recently infected with HIV.Q46277555
Prevalence of transmitted drug resistance associated mutations and HIV-1 subtypes in new HIV-1 diagnoses, U.S.-2006.Q46520376
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectviral loadQ2528140
P304page(s)e109420
P577publication date2014-01-01
P1433published inPLOS OneQ564954
P1476titleA significant reduction in the frequency of HIV-1 drug resistance in Québec from 2001 to 2011 is associated with a decrease in the monitored viral load
P478volume9

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cites work (P2860)
Q33664179A decade of viral mutations and associated drug resistance in a population of HIV-1+ Puerto Ricans: 2002-2011
Q64058710Assessing the role of transmission chains in the spread of HIV-1 among men who have sex with men in Quebec, Canada
Q38898453Clinical benefit of dolutegravir in HIV-1 management related to the high genetic barrier to drug resistance
Q92016273Delayed linkage to HIV care among asylum seekers in Quebec, Canada
Q47560008Genotypic and Phylogenetic Insights on Prevention of the Spread of HIV-1 and Drug Resistance in "Real-World" Settings
Q30245693HIV-1 drug resistance and resistance testing
Q40215127HIV-1 strains belonging to large phylogenetic clusters show accelerated escape from integrase inhibitors in cell culture compared with viral isolates from singleton/small clusters