Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins

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Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins is …
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P356DOI10.1371/JOURNAL.PPAT.1005277
P3181OpenCitations bibliographic resource ID2707624
P932PMC publication ID4643051
P698PubMed publication ID26562291
P5875ResearchGate publication ID283728111

P50authorPietro ScaturroQ55186626
Mirko CorteseQ55186628
Ralf BartenschlagerQ20664754
P2093author name stringWolfgang Fischl
Laurent Chatel-Chaix
P2860cites workThe global distribution and burden of dengueQ24628768
Architecture and biogenesis of plus-strand RNA virus replication factoriesQ26824445
trans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cellsQ27469561
cis- and trans-acting elements in flavivirus RNA replicationQ27469649
Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function.Q27469704
Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashionQ27469716
Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicaseQ27469756
The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivityQ27470900
Mutations in the Yellow Fever Virus Nonstructural Protein NS2A Selectively Block Production of Infectious ParticlesQ27472873
Differential Biophysical Properties of Infectious Intracellular and Secreted Hepatitis C Virus ParticlesQ27477620
West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor HQ27477691
Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral GenomesQ27480348
Monoclonal Antibodies That Bind to Common Epitopes on the Dengue Virus Type 2 Nonstructural-1 and Envelope Glycoproteins Display Weak Neutralizing Activity and Differentiated Responses to Virulent Strains: Implications for Pathogenesis and VaccinesQ27485490
trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replicationQ27485867
Construction of an infectious cDNA clone for a Brazilian prototype strain of dengue virus type 1: Characterization of a temperature-sensitive mutation in NS1Q27486156
Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like ParticlesQ27486405
West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal TransductionQ27486783
Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune SystemQ27681625
Structural basis of Flavivirus NS1 assembly and antibody recognitionQ27681981
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
Composition and three-dimensional architecture of the dengue virus replication and assembly sitesQ29615112
Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replicationQ29616271
Growth of human hepatoma cells lines with differentiated functions in chemically defined mediumQ29617962
Structural changes and functional control of the tick-borne encephalitis virus glycoprotein E by the heterodimeric association with protein prMQ29618178
Characterization of the mode of action of a potent dengue virus capsid inhibitorQ30365058
Ultrastructural characterization and three-dimensional architecture of replication sites in dengue virus-infected mosquito cellsQ30576592
Determination of the disulfide bond arrangement of dengue virus NS1 proteinQ33198586
Antagonism of the complement component C4 by flavivirus nonstructural protein NS1.Q33795001
Maintenance of dimer conformation by the dengue virus core protein α4-α4' helix pair is critical for nucleocapsid formation and virus productionQ33900372
Amphipathic alpha-helix AH2 is a major determinant for the oligomerization of hepatitis C virus nonstructural protein 4BQ34416649
(+)RNA viruses rewire cellular pathways to build replication organellesQ34433756
Highly conserved residues in the helical domain of dengue virus type 1 precursor membrane protein are involved in assembly, precursor membrane (prM) protein cleavage, and entryQ34580259
Coupling of replication and assembly in flavivirusesQ34716805
N-linked glycosylation of dengue virus NS1 protein modulates secretion, cell-surface expression, hexamer stability, and interactions with human complementQ34952610
Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoproteinQ34977722
Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activationQ35058899
NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexesQ35077749
A basic cluster in the N terminus of yellow fever virus NS2A contributes to infectious particle productionQ35488765
A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral ReplicationQ35758578
Evidence for a genetic and physical interaction between nonstructural proteins NS1 and NS4B that modulates replication of West Nile virusQ36155471
Inhibition of cellular autophagy deranges dengue virion maturationQ36559936
Nuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signalingQ36760135
NS1' colocalizes with NS1 and can substitute for NS1 in West Nile virus replicationQ37123358
Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesisQ37348012
Mutagenesis of the N-linked glycosylation sites of the yellow fever virus NS1 protein: effects on virus replication and mouse neurovirulenceQ38354618
The dengue virus nonstructural-1 protein (NS1) generates antibodies to common epitopes on human blood clotting, integrin/adhesin proteins and binds to human endothelial cells: potential implications in haemorrhagic fever pathogenesisQ38998233
High-throughput screening using dengue virus reporter genomesQ39131341
Class II ADP-ribosylation factors are required for efficient secretion of dengue virusesQ39439279
A short N-terminal peptide motif on flavivirus nonstructural protein NS1 modulates cellular targeting and immune recognitionQ39686453
KDEL Receptors Assist Dengue Virus Exit from the Endoplasmic ReticulumQ40166114
RNA binding property and RNA chaperone activity of dengue virus core protein and other viral RNA-interacting proteins.Q40317940
Proteomic analysis of endothelial cell autoantigens recognized by anti-dengue virus nonstructural protein 1 antibodiesQ40405263
Secreted complement regulatory protein clusterin interacts with dengue virus nonstructural protein 1.Q40439853
Synergistic Interactions of Anti-NS1 Monoclonal Antibodies Protect Passively Immunized Mice from Lethal Challenge with Dengue 2 VirusQ40784132
Evidence that the mature form of the flavivirus nonstructural protein NS1 is a dimerQ40791245
Analyses of the terminal sequences of West Nile virus structural proteins and of the in vitro translation of these proteins allow the proposal of a complete scheme of the proteolytic cleavages involved in their synthesisQ41853781
Aurora B-mediated abscission checkpoint protects against tetraploidizationQ42810739
The synthesis and maturation of a non-structural extracellular antigen from tick-borne encephalitis virus and its relationship to the intracellular NS1 proteinQ42989038
Maturation of Japanese encephalitis virus glycoproteins produced by infected mammalian and mosquito cellsQ42989189
The NS1 protein of tick-borne encephalitis virus forms multimeric species upon secretion from the host cellQ43036438
A novel complex formed between the flavivirus E and NS1 proteins: analysis of its structure and functionQ43038187
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectDengue virusQ476209
virion assemblyQ14916420
dengue virus protein NS1Q114697989
P304page(s)e1005277
P577publication date2015-01-01
P1433published inPLOS PathogensQ283209
P1476titleDengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins
P478volume11

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