Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology

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Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1005559
P3181OpenCitations bibliographic resource ID2416662
P932PMC publication ID4825991
P698PubMed publication ID27058585
P5875ResearchGate publication ID300006238

P50authorCarolyn BertozziQ7442
Juan MucciQ39986272
Carlos A. BuscagliaQ39986315
Oscar CampetellaQ42880981
P2093author name stringXi Chen
Hai Yu
Mariano Bossi
Andrés B Lantos
Giannina Carlevaro
Beatriz Araoz
María de Los Milagros Camara
Pablo Ruiz Diaz
P2860cites workRapid Cu-free click chemistry with readily synthesized biarylazacyclooctynonesQ24623486
Copper-free click chemistry for dynamic in vivo imagingQ24675560
Membrane curvature at a glanceQ27016570
TcTASV-C, a protein family in Trypanosoma cruzi that is predominantly trypomastigote-stage specific and secreted to the mediumQ27309739
Rab11 regulates trafficking of trans-sialidase to the plasma membrane through the contractile vacuole complex of Trypanosoma cruziQ27324721
Identification of contractile vacuole proteins in Trypanosoma cruziQ27349403
Trypanosoma cruzi trans-Sialidase in Complex with a Neutralizing Antibody: Structure/Function Studies towards the Rational Design of InhibitorsQ27676712
Chemical remodelling of cell surfaces in living animalsQ28277825
Chemistry in living systemsQ28291334
Lytic anti-alpha-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosyl-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruziQ28368291
The repetitive cytoskeletal protein H49 of Trypanosoma cruzi is a calpain-like protein located at the flagellum attachment zoneQ28477942
Precise nanometer localization analysis for individual fluorescent probesQ29617300
Membrane curvature and mechanisms of dynamic cell membrane remodellingQ29617321
How proteins produce cellular membrane curvatureQ29618016
Evaluation of fluorophores for optimal performance in localization-based super-resolution imagingQ30504713
A multifunctional Pasteurella multocida sialyltransferase: a powerful tool for the synthesis of sialoside librariesQ33229334
Fluorescence nanoscopy by ground-state depletion and single-molecule returnQ33369726
Imaging biological structures with fluorescence photoactivation localization microscopyQ33408754
Genomic organization and expression profile of the mucin-associated surface protein (masp) family of the human pathogen Trypanosoma cruziQ33425111
Membrane raft association is a determinant of plasma membrane localizationQ33767581
Rab23 is a flagellar protein in Trypanosoma bruceiQ33933614
Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylationQ33979079
Immunization of mice with a TolA-like surface protein of Trypanosoma cruzi generates CD4(+) T-cell-dependent parasiticidal activity.Q34001763
Genomic analyses, gene expression and antigenic profile of the trans-sialidase superfamily of Trypanosoma cruzi reveal an undetected level of complexity.Q34062280
Acylation-dependent export of Trypanosoma cruzi phosphoinositide-specific phospholipase C to the outer surface of amastigotesQ34155407
Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins.Q44316258
Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruziQ44896476
Differential expression of a virulence factor, the trans-sialidase, by the main Trypanosoma cruzi phylogenetic lineagesQ47384939
The Trypanosoma cruzi mucin family is transcribed from hundreds of genes having hypervariable regions.Q48037712
A novel phosphatidylinositol-phospholipase C of Trypanosoma cruzi that is lipid modified and activated during trypomastigote to amastigote differentiation.Q52170643
Role of sialic acid in the resistance of Trypanosoma cruzi trypomastigotes to complement.Q54193252
The flagellar adenylate kinases of Trypanosoma cruzi.Q55063250
Trypanosoma cruzi: parasite shed vesicles increase heart parasitism and generate an intense inflammatory responseQ57067411
Trypanosoma cruzi: Shedding of surface antigens as membrane vesiclesQ57067573
Mucin-like glycoproteins linked to the membrane by glycosylphosphatidylinositol anchor are the major acceptors of sialic acid in a reaction catalyzed by trans-sialidase in metacyclic forms of Trypanosoma cruziQ57935072
Immunocharacterization of the mucin-type proteins from the intracellular stage of Trypanosoma cruziQ58845376
The surface coat of the mammal-dwelling infective trypomastigote stage of Trypanosoma cruzi is formed by highly diverse immunogenic mucinsQ58845802
The Surface Coat of the Mammal-dwelling Infective Trypomastigote Stage ofTrypanosoma cruziIs Formed by Highly Diverse Immunogenic MucinsQ58855119
Visualization of the flagellar surface of protists by atomic force microscopyQ84761624
The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles.Q34264871
Molecular and electrophysiological characterization of a novel cation channel of Trypanosoma cruziQ34299402
Implications of lipid microdomains for membrane curvature, budding and fissionQ34309080
Raft domains of variable properties and compositions in plasma membrane vesiclesQ35105065
Membrane organization and lipid raftsQ35230032
Trypanosoma cruzi trans-sialidase prevents elicitation of Th1 cell response via interleukin 10 and downregulates Th1 effector cellsQ35439736
Altering the motility of Trypanosoma cruzi with rabbit polyclonal anti-peptide antibodies reduces infection to susceptible mammalian cells.Q35551345
Formation and remodeling of inositolphosphoceramide during differentiation of Trypanosoma cruzi from trypomastigote to amastigoteQ35612945
Multigene families in Trypanosoma cruzi and their role in infectivityQ36156052
A Trypanosoma cruzi small surface molecule provides the first immunological evidence that Chagas' disease is due to a single parasite lineageQ36369928
Trypanosoma cruzi surface mucins: host-dependent coat diversityQ36401388
Macro, micro and nano domains in the membrane of parasitic protozoaQ36755091
Actin mediates the nanoscale membrane organization of the clustered membrane protein influenza hemagglutininQ36864524
Flagellar membrane localization via association with lipid raftsQ37271610
Glycobiology of Trypanosoma cruziQ37510071
Structural organization of Trypanosoma cruziQ37597049
Trans-sialidase and mucins of Trypanosoma cruzi: an important interplay for the parasiteQ37885531
T rypanosoma cruzi trans-sialidase as a multifunctional enzyme in Chagas' diseaseQ38022759
Trypanosoma cruzi Trans-sialidase: structural features and biological implicationsQ38165063
Mucin-like molecules form a negatively charged coat that protects Trypanosoma cruzi trypomastigotes from killing by human anti-alpha-galactosyl antibodiesQ38314745
The N-linked carbohydrate chain of the 85-kilodalton glycoprotein from Trypanosoma cruzi trypomastigotes contains sialyl, fucosyl and galactosyl (alpha 1-3)galactose unitsQ38342188
Developmental expression of a Trypanosoma cruzi phosphoinositide-specific phospholipase C in amastigotes and stimulation of host phosphoinositide hydrolysisQ39220157
Molecular diversity of the Trypanosoma cruzi TcSMUG family of mucin genes and proteinsQ39986212
Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emittersQ40101186
Stage-specific expression and intracellular shedding of the cell surface trans-sialidase of Trypanosoma cruziQ40146889
Mice infected with Trypanosoma cruzi produce antibodies against the enzymatic domain of trans-sialidase that inhibit its activity.Q40374953
Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agentsQ40410786
Structural and functional properties of Trypanosoma trans-sialidaseQ40572972
Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages.Q41104715
Trypanosoma cruzi trans-sialidase and neuraminidase activities can be mediated by the same enzymesQ42029468
Ultrastructure of Trypanosoma cruzi revisited by atomic force microscopyQ42521322
Developmentally regulated, phospholipase C-mediated release of the major surface glycoprotein of amastigotes of Trypanosoma cruziQ42939016
Effect of the structure of natural sterols and sphingolipids on the formation of ordered sphingolipid/sterol domains (rafts). Comparison of cholesterol to plant, fungal, and disease-associated sterols and comparison of sphingomyelin, cerebrosides, aQ43658464
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectphysiologyQ521
Trypanosoma cruziQ150162
glycobiologyQ899224
trypomastigoteQ106395156
P304page(s)e1005559
P577publication date2016-04-01
P1433published inPLOS PathogensQ283209
P1476titleSialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology
P478volume12

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