Crystal Structure of a Ube2S-Ubiquitin Conjugate

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Crystal Structure of a Ube2S-Ubiquitin Conjugate is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1147550L
P356DOI10.1371/JOURNAL.PONE.0147550
P3181OpenCitations bibliographic resource ID3215076
P932PMC publication ID4734694
P698PubMed publication ID26828794
P5875ResearchGate publication ID292676757

P50authorJohn KuriyanQ6243502
Sonja Gisela LorenzQ21264700
Michael RapeQ55163233
P2093author name stringMoitrayee Bhattacharyya
Christian Feiler
P2860cites workThe mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2Q24294888
Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8Q24299638
Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machineQ24317405
UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exitQ24324253
Identification of a physiological E2 module for the human anaphase-promoting complexQ24328862
Ubiquitin in motion: structural studies of the ubiquitin-conjugating enzyme∼ubiquitin conjugateQ34666396
Macromolecular juggling by ubiquitylation enzymesQ34782977
Distinct activation of an E2 ubiquitin-conjugating enzyme by its cognate E3 ligasesQ35128799
Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.Q36291328
Activation of UbcH5c~Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B.Q36882621
Ubiquitin chain elongation requires E3-dependent tracking of the emerging conjugateQ38948774
Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chainsQ42095239
Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.Q43074598
Ubiquitin manipulation by an E2 conjugating enzyme using a novel covalent intermediate.Q46598593
GROMACS: A message-passing parallel molecular dynamics implementationQ51756282
Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase CezanneQ24338586
Improved side-chain torsion potentials for the Amber ff99SB protein force fieldQ24616749
PHENIX: a comprehensive Python-based system for macromolecular structure solutionQ24654617
Atomic structure of the APC/C and its mechanism of protein ubiquitinationQ27316585
Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tailQ27635260
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclaseQ27652454
The structure of the UbcH8-ubiquitin complex shows a unique ubiquitin interaction siteQ27658283
Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L ComplexQ27658921
Crystal structure of UbcH5b~ubiquitin intermediate: insight into the formation of the self-assembled E2~Ub conjugatesQ27659805
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysisQ27670947
BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimerQ27671574
Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2Q27676384
OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme FunctionQ27677192
The mechanism of OTUB1-mediated inhibition of ubiquitinationQ27677504
A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function ScreenQ27678481
Structural Insights into the Conformation and Oligomerization of E2∼Ubiquitin ConjugatesQ27678872
Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3Q27679081
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitinQ27680817
Structural basis for the inhibition of host protein ubiquitination by Shigella effector kinase OspGQ27690286
Activation of a primed RING E3-E2-ubiquitin complex by non-covalent ubiquitinQ27700027
XDSQ27860472
Coot: model-building tools for molecular graphicsQ27860505
Overview of the CCP4 suite and current developmentsQ27860782
NMRPipe: a multidimensional spectral processing system based on UNIX pipesQ27860859
Phasercrystallographic softwareQ27860930
The ubiquitin codeQ28265104
Essential role for ubiquitin-ubiquitin-conjugating enzyme interaction in ubiquitin discharge from Cdc34 to substrateQ28740322
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkitQ29615867
HADDOCK versus HADDOCK: new features and performance of HADDOCK2.0 on the CAPRI targetsQ29615981
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complexQ29617624
Building ubiquitin chains: E2 enzymes at workQ29619578
Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formationQ29619698
Improved sensitivity of HSQC spectra of exchanging protons at short interscan delays using a new fast HSQC (FHSQC) detection scheme that avoids water saturationQ29619727
Molecular architecture and mechanism of the anaphase-promoting complexQ30653286
UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complexQ33575426
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcrystal structureQ895901
P304page(s)e0147550
P577publication date2016-01-01
P1433published inPLOS OneQ564954
P1476titleCrystal Structure of a Ube2S-Ubiquitin Conjugate
P478volume11

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cites work (P2860)
Q64229270Analysis of ubiquitin recognition by the HECT ligase E6AP provides insight into its linkage specificity
Q92105561Enzymatic Logic of Ubiquitin Chain Assembly
Q58089566Hepatitis C virus downregulates ubiquitin conjugating enzyme E2S expression to prevent proteasomal degradation of NS5A, leading to host cells more sensitive to DNA damage
Q94600140Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination
Q28067393Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3
Q92645188Ube2s expression is elevated in hepatocellular carcinoma and predicts poor prognosis of the patients
Q26751380Ubiquitin modifications
Q39149390Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism

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