AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells

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AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1167848Y
P356DOI10.1371/JOURNAL.PONE.0167848
P932PMC publication ID5148003
P698PubMed publication ID27936102

P50authorAkio KiharaQ42656232
P2093author name stringToru Nakano
Kenichi Higashino
Yoshito Numata
Shoichi Naito
Tomoyo Yoshinaga
Kenichiro Uwabe
P2860cites workThe renin-angiotensin system contributes to renal fibrosis through regulation of fibrocytesQ46713511
A new Twist in kidney fibrosisQ48137535
123I-labeled AM251: a radioiodinated ligand which binds in vivo to mouse brain cannabinoid CB1 receptorsQ48966515
Chronic administration of AM251 improves albuminuria and renal tubular structure in obese rats.Q50592702
Cannabinoid receptor 1 disturbance of PPARγ2 augments hyperglycemia induction of mesangial inflammation and fibrosis in renal glomeruli.Q52649284
Cannabinoid receptor 1 is a major mediator of renal fibrosis.Q53587541
Transforming growth factor-beta-induced alpha-smooth muscle cell actin expression in renal proximal tubular cells is regulated by p38beta mitogen-activated protein kinase, extracellular signal-regulated protein kinase1,2 and the Smad signalling durinQ64376822
Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodelingQ79339898
The RIN: an RNA integrity number for assigning integrity values to RNA measurementsQ21263010
Epithelial-mesenchymal transition and its implications for fibrosisQ24302042
A new type of transforming growth factor-beta, TGF-beta 3Q24564095
The endocannabinoid system as an emerging target of pharmacotherapyQ24648473
The basics of epithelial-mesenchymal transitionQ24652992
The orphan receptor GPR55 is a novel cannabinoid receptorQ24670137
Molecular mechanisms of epithelial-mesenchymal transitionQ27013743
Myofibroblasts and mechano-regulation of connective tissue remodellingQ28216468
Identification of GPR55 as a lysophosphatidylinositol receptorQ28244299
The role of the p38 MAPK signaling pathway in high glucose-induced epithelial-mesenchymal transition of cultured human renal tubular epithelial cellsQ28476375
Evidence that fibroblasts derive from epithelium during tissue fibrosisQ29616581
TGF-beta-induced epithelial to mesenchymal transitionQ29619820
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosisQ33556248
TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transitionQ33734595
Origin and function of myofibroblasts in kidney fibrosisQ33792700
A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function.Q34342626
Cellular and molecular mechanisms of renal fibrosisQ35903772
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosisQ36104434
Fibroblast activation and myofibroblast generation in obstructive nephropathyQ37498285
Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effectsQ37959379
Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney diseaseQ38083596
TGF-β isoforms induce EMT independent migration of ovarian cancer cellsQ38950894
The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells.Q40357523
Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.Q40464612
Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established diseaseQ40666383
Hepatocyte-derived Snail1 propagates liver fibrosis progressionQ41865587
Endocannabinoids in nervous system health and disease: the big picture in a nutshellQ42112685
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageQuantQ112270642
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)e0167848
P577publication date2016-01-01
P1433published inPLOS OneQ564954
P1476titleAM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells
P478volume11

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cites work (P2860)
Q923705482-arachidonoylglycerol reduces chondroitin sulphate proteoglycan production by astrocytes and enhances oligodendrocyte differentiation under inhibitory conditions
Q49798105Benzidine Induces Epithelial-Mesenchymal Transition of Human Bladder Cancer Cells through Activation of ERK5 Pathway
Q33687409Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer.
Q64229253Effects of UPF1 expression on EMT process by targeting E‑cadherin, N‑cadherin, Vimentin and Twist in a hepatocellular carcinoma cell line
Q48279308Opposite actions of urotensin II and relaxin-2 on cellular expression of fibronectin in renal fibrosis: A preliminary experimental study
Q47694616Photobiomodulation Therapy Improves Acute Inflammatory Response in Mice: the Role of Cannabinoid Receptors/ATP-Sensitive K(+) Channel/p38-MAPK Signalling Pathway

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