Fatty acids-stress attenuates gluconeogenesis induction and glucose production in primary hepatocytes

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Fatty acids-stress attenuates gluconeogenesis induction and glucose production in primary hepatocytes is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1037338440
P356DOI10.1186/1476-511X-11-66
P932PMC publication ID3391994
P698PubMed publication ID22676303
P5875ResearchGate publication ID225281558

P2093author name stringZecharia Madar
Oren Tirosh
Sarit Anavi
Noga Budick-Harmelin
P2860cites workThe role of HNF1alpha, HNF3gamma, and cyclic AMP in glucose-6-phosphatase gene activationQ24336697
An analysis of regulatory elements in the phosphoenolpyruvate carboxykinase (GTP) gene which are responsible for its tissue-specific expression and metabolic control in transgenic miceQ72272453
Mitochondrial reactive oxygen species signal hepatocyte steatosis by regulating the phosphatidylinositol 3-kinase cell survival pathwayQ80411962
A general introduction to the biochemistry of mitochondrial fatty acid β-oxidationQ26699142
Transcriptional regulation by the phosphorylation-dependent factor CREBQ28210623
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1Q28216275
Long-chain fatty acids regulate liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome-proliferator-activated receptor alpha (PPARalpha)-independent pathwayQ28348167
The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB)Q28572804
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1Q29615692
Mechanism for the stimulation of gluconeogenesis by fatty acids in perfused rat liverQ33799804
The effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjectsQ33836122
Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humansQ33903864
Fatty acid regulation of gene transcriptionQ33996658
Mitochondrial fatty acid oxidation disorders: pathophysiological studies in mouse modelsQ34163820
Control of mitochondrial beta-oxidation fluxQ34508227
Evaluation of free fatty acid metabolism in vivo.Q34702034
Is there a single mechanism for fatty acid regulation of gene transcription?Q34816136
Mechanisms of the free fatty acid-induced increase in hepatic glucose productionQ35099530
Novel concepts in insulin regulation of hepatic gluconeogenesisQ35213690
Role of the liver in the control of carbohydrate and lipid homeostasisQ36020648
Mitochondrial fatty-acid oxidation disordersQ37245445
Pathophysiology of fatty acid oxidation disordersQ37786229
Identification of a cAMP response element within the glucose- 6-phosphatase hydrolytic subunit gene promoter which is involved in the transcriptional regulation by cAMP and glucocorticoids in H4IIE hepatoma cellsQ38328020
Lipotoxic effects of triacylglycerols in J774.2 macrophagesQ40029374
Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicityQ40379756
Glucose fatty acid interactions and the regulation of glucose disposalQ40634209
Inhibitory effect of plasma free fatty acids on glucose production in the conscious dogQ41535432
Regulation of gene transcription by fatty acids, fibrates and prostaglandins: the phosphoenolpyruvate carboxykinase gene as a model.Q41557177
Stimulation of phosphoenolpyruvate carboxykinase gene expression by fatty acidsQ42496874
Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed ratsQ42512039
Transcriptional regulation of p90 with sequence homology to Escherichia coli glycerol-3-phosphate acyltransferaseQ42617216
Effects of free fatty acids on gluconeogenesis and autoregulation of glucose production in type 2 diabetesQ43566160
Mitochondrial redox state and the regulation of gluconeogenesis in the isolated, perfused cat liverQ43757218
Polyunsaturated fatty acyl coenzyme A suppress the glucose-6-phosphatase promoter activity by modulating the DNA binding of hepatocyte nuclear factor 4 alpha.Q43895794
Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sitesQ44280864
Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alphaQ44547321
Palmitate potentiation of glucose-induced insulin release: a study using 2-bromopalmitateQ44621535
Effects of oleate, palmitate, and octanoate on gluconeogenesis in isolated rabbit liver cellsQ45043125
Triglycerides potentiate the inflammatory response in rat Kupffer cells.Q46424300
Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytesQ46685648
Development and regulation of glucose-6-phosphatase gene expression in rat liver, intestine, and kidney: in vivo and in vitro studies in cultured fetal hepatocytesQ48460010
Role of fat-derived substrates in the regulation of gluconeogenesis during fasting.Q51581463
Control of gluconeogenesis in liver. IV. Differential effects of fatty acids and glucagon on ketogenesis and gluconeogenesis in the perfused rat liver.Q51685942
p38 Mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes.Q53594219
Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin geneQ59084755
Control of hepatic gluconeogenesis: role of fatty acid oxidationQ69595617
P921main subjectglucoseQ37525
gluconeogenesisQ191835
P304page(s)66
P577publication date2012-07-09
P1433published inLipids in Health and DiseaseQ15756695
P1476titleFatty acids-stress attenuates gluconeogenesis induction and glucose production in primary hepatocytes
P478volume11

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cites work (P2860)
Q64069791Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acid
Q39623084L-arginine conjugates of bile acids-a possible treatment for non-alcoholic fatty liver disease
Q64080514Metformin attenuates the onset of non-alcoholic fatty liver disease and affects intestinal microbiota and barrier in small intestine
Q38760996Modulation of cAMP levels by high-fat diet and curcumin and regulatory effects on CD36/FAT scavenger receptor/fatty acids transporter gene expression.
Q38075862Molecular mechanisms of hypolipidemic effects of curcumin