N-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses

scientific journal article

N-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M801555200
P3181OpenCitations bibliographic resource ID4629652
P932PMC publication ID2414292
P698PubMed publication ID18430734

P50authorAdam M WegnerQ58150659
Alissa M. WeaverQ87871173
P2093author name stringCaroline A Nebhan
Donna J Webb
Lan Hu
Devi Majumdar
Kristen M Meier
P2860cites workDevelopmental expression of neural Wiskott-Aldrich syndrome protein (N-WASP) and WASP family verprolin-homologous protein (WAVE)-related proteins in postnatal rat cerebral cortex and hippocampusQ48393641
Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors.Q48493391
Activity-induced rapid synaptic maturation mediated by presynaptic cdc42 signaling.Q48555006
Rapid formation and remodeling of postsynaptic densities in developing dendritesQ48774312
Dendritic Spine Pathology: Cause or Consequence of Neurological Disorders?Q58064430
Activity-dependent fluorescent staining and destaining of living vertebrate motor nerve terminalsQ67531875
Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and RhoQ73010224
The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocationQ24293287
Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerizationQ24309118
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.Q24541317
The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filamentsQ24653380
Synapse formation is regulated by the signaling adaptor GIT1Q24675182
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilinQ24678564
A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerizationQ28139787
The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42Q28181795
Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenesQ28301594
Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulationQ28568741
A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLCQ28574525
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assemblyQ28609843
N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinasesQ29614248
Evidence for a role of dendritic filopodia in synaptogenesis and spine formationQ29616333
The WASP-WAVE protein network: connecting the membrane to the cytoskeletonQ29616493
The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPaseQ30438135
Selective clustering of glutamate and gamma-aminobutyric acid receptors opposite terminals releasing the corresponding neurotransmittersQ30453983
Filopodia formation in the absence of functional WAVE- and Arp2/3-complexesQ30477396
Developmental regulation of spine motility in the mammalian central nervous systemQ30482070
Monitoring secretory membrane with FM1-43 fluorescenceQ33593382
Structure, development, and plasticity of dendritic spinesQ33680903
Actin-based plasticity in dendritic spinesQ34071209
Molecular mechanisms of dendritic spine development and remodelingQ34417235
Synaptogenesis via dendritic filopodia in developing hippocampal area CA1.Q34476864
Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP.Q35820542
High actin concentrations in brain dendritic spines and postsynaptic densitiesQ36325303
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complexQ36450248
A neural Wiskott-Aldrich Syndrome protein-mediated pathway for localized activation of actin polymerization that is regulated by cortactinQ40484725
N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factorQ40501703
Imaging exocytosis and endocytosisQ40937794
Rapid actin-based plasticity in dendritic spinesQ41035734
The Wiskott-Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complexQ41667056
Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.Q41734676
Sequential implication of the mental retardation proteins ARHGEF6 and PAK3 in spine morphogenesisQ42833666
Optical analysis of synaptic vesicle recycling at the frog neuromuscular junctionQ43552239
Small GTPase Cdc42 Is Required for Multiple Aspects of Dendritic MorphogenesisQ45983104
The kinetics of synaptic vesicle recycling measured at single presynaptic boutonsQ46230329
Serotonin-induced regulation of the actin network for learning-related synaptic growth requires Cdc42, N-WASP, and PAK in Aplysia sensory neuronsQ46410223
The dynamics of dendritic structure in developing hippocampal slices.Q46418630
Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformationQ47244406
The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesisQ47913103
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectdendritic spineQ902079
P304page(s)15912-15920
P577publication date2008-04-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleN-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses
P478volume283

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