Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes

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Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M002252200
P3181OpenCitations bibliographic resource ID3232396
P698PubMed publication ID10938268

P50authorTudor LuchianQ48585129
P2093author name stringL. Thomas
A. Jones
D. J. Adams
P. R. Andrews
T. Bond
R. J. Lewis
D. A. Adams
M. L. Loughnan
D. J. Craik
I. A. Sharpe
J. L. Matheson
K. J. Nielsen
P. F. Alewood
R. Drinkwater
P2860cites workStructure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channelsQ27618721
Structural and dynamic characterization of omega-conotoxin MVIIA: the binding loop exhibits slow conformational exchangeQ27622048
Solution structure of omega-conotoxin GVIA using 2-D NMR spectroscopy and relaxation matrix analysisQ27731960
A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202Q27733890
Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIAQ27748801
Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stabilityQ27756877
Torsion angle dynamics: reduced variable conformational sampling enhances crystallographic structure refinementQ28242162
A new Conus peptide ligand for mammalian presynaptic Ca2+ channelsQ28327603
Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using omega-conotoxin from Conus magus venomQ28338203
Hyperpolarization and inhibition of contraction mediated by nitric oxide released from enteric inhibitory neurones in guinea-pig taenia coliQ28396190
beta subunits influence the biophysical and pharmacological differences between P- and Q-type calcium currents expressed in a mammalian cell lineQ33743657
Structure-activity relationships of omega-conotoxins at N-type voltage-sensitive calcium channelsQ33902745
Novel alpha- and omega-conotoxins from Conus striatus venomQ34252509
Beta subunit heterogeneity in N-type Ca2+ channels.Q34378158
Three-dimensional structure of proteins determined by molecular dynamics with interproton distance restraints: application to crambinQ35608131
Inhibition of neurally-evoked transmitter release by calcium channel antagonists in rat parasympathetic gangliaQ35756694
A Xenopus oocyte beta subunit: evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunitQ36020266
Antagonists of neuronal calcium channels: structure, function, and therapeutic implicationsQ39479175
Roles of key functional groups in omega-conotoxin GVIA synthesis, structure and functional assay of selected peptide analoguesQ40812837
Structure-function relationships of omega-conotoxin GVIA. Synthesis, structure, calcium channel binding, and functional assay of alanine-substituted analogues.Q42550039
Characterization of the purified N-type Ca2+ channel and the cation sensitivity of omega-conotoxin GVIA binding.Q42602022
Precursor structure of omega-conotoxin GVIA determined from a cDNA cloneQ44642667
Peptide neurotoxins from fish-hunting cone snailsQ44887405
Characterization of the binding of omega-conopeptides to different classes of non-L-type neuronal calcium channelsQ46065077
Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxinQ46111206
Structures and functions of calcium channel beta subunitsQ46459475
Effect of continuous intrathecal infusion of omega-conopeptides, N-type calcium-channel blockers, on behavior and antinociception in the formalin and hot-plate tests in ratsQ46978379
Identification of functionally distinct isoforms of the N-type Ca2+ channel in rat sympathetic ganglia and brainQ48056255
Omega-conotoxin GVIA protects against ischemia-induced neuronal death in the Mongolian gerbil but not against quinolinic acid-induced neurotoxicity in the rat.Q48184597
Structure-activity studies of conantokins as human N-methyl-D-aspartate receptor modulatorsQ48284703
Peripheral versus central potencies of N-type voltage-sensitive calcium channel blockersQ48499005
Folding of omega-conotoxins. 2. Influence of precursor sequences and protein disulfide isomeraseQ48831347
Different types of calcium channels mediate central synaptic transmissionQ59054415
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectConus catusQ913419
P304page(s)35335–35344
P577publication date2000-11-10
P1433published inJournal of Biological ChemistryQ867727
P1476titleNovel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes
P478volume275