Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

scientific journal article

Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1005783445
P356DOI10.1186/1744-8069-4-19
P932PMC publication ID2430948
P698PubMed publication ID18510735
P5875ResearchGate publication ID5339689

P50authorPierre VeinanteQ55856377
Pierrick PoisbeauQ55856381
P2093author name stringAngela Maria Vergnano
Jean-Didier Breton
Marie José Freund-Mercier
Rémy Schlichter
Sandra Uhl-Bronner
P2860cites workEffects of hypothalamic paraventricular nucleus: electrical stimulation produce marked analgesia in ratsQ71230050
Immunohistochemistry of vasopressin, oxytocin and neurophysin in the hypothalamus and extrahypothalamic regions of the human and primate brainQ71548759
Intrathecal oxytocin facilitates the spinal nociceptive flexor reflex in the ratQ72032089
Anti-nociceptive effects of oxytocin in rats and miceQ72084537
Localization of oxytocin binding sites in the thoracic and upper lumbar spinal cord of the adult and postnatal rat: a histoautoradiographic studyQ72299374
Oxytocin actions on afferent evoked spinal cord neuronal activities in neuropathic but not in normal ratsQ81775638
Oxytocin and electrical stimulation of the paraventricular hypothalamic nucleus produce antinociceptive effects that are reversed by an oxytocin antagonistQ82778446
The oxytocin receptor system: structure, function, and regulationQ28207331
Oxytocinergic innervation of autonomic nuclei controlling penile erection in the rat.Q30779906
Speaking out of turn: a role for silent synapses in painQ33847974
'Deaf, mute and whispering' silent synapses: their role in synaptic plasticityQ34307442
Direct hypothalamo-autonomic connectionsQ39407341
The distribution of oxytocin- and neurophysin-stained fibers in the spinal cord of the rat and monkeyQ39694622
Stimulation of the hypothalamic paraventricular nucleus produces analgesia not mediated by vasopressin or endogenous opioidsQ41827661
[3H]-[Thr4,Gly7]OT: a highly selective ligand for central and peripheral OT receptorsQ42200169
Oxytocin modulates glutamatergic synaptic transmission between cultured neonatal spinal cord dorsal horn neurons.Q42544499
Neurochemical organization of the hypothalamic projection to the spinal cord in the rat.Q43550963
Oxytocinergic innervation of the rat spinal cord. An electron microscopic studyQ43623881
Activation of silent synapses by rapid activity-dependent synaptic recruitment of AMPA receptors.Q43697226
Oxytocin decreases carrageenan induced inflammation in ratsQ43713625
Region-specific developmental specialization of GABA-glycine cosynapses in laminas I-II of the rat spinal dorsal horn.Q43757430
Actions of oxytocin and interactions with glutamate on spontaneous and evoked dorsal spinal cord neuronal activities.Q44451584
Involvement of oxytocin in spinal antinociception in rats with inflammationQ44546947
Production of 5alpha-reduced neurosteroids is developmentally regulated and shapes GABA(A) miniature IPSCs in lamina II of the spinal cord.Q44746567
Paraventricular hypothalamic influences on spinal nociceptive processing.Q46959872
Silent glutamatergic synapses and nociception in mammalian spinal cordQ47924223
125I-labelled d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH2(9)]OVT: a selective oxytocin receptor ligandQ48109068
Oxytocin modulates the effects of galanin in carrageenan-induced hyperalgesia in ratsQ48303018
GABA-mediated oxytocinergic inhibition in dorsal horn neurons by hypothalamic paraventricular nucleus stimulationQ48307291
Repeated massage-like stimulation induces long-term effects on nociception: contribution of oxytocinergic mechanismsQ48517000
Olfactory cues from an oxytocin-injected male rat can induce anti-nociception in its cagematesQ48618108
Vasopressin and oxytocin in the rat spinal cord: analysis of their role in the control of nociceptionQ48622850
Oxytocin mediates stress-induced analgesia in adult miceQ48629839
P407language of work or nameEnglishQ1860
P921main subjectoxytocinQ169960
P304page(s)19
P577publication date2008-05-29
P1433published inMolecular PainQ15766244
P1476titleOxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition
P478volume4

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cites work (P2860)
Q33767128Analgesic strategies aimed at stimulating the endogenous production of allopregnanolone
Q37428171Antinociceptive action of oxytocin involves inhibition of potassium channel currents in lamina II neurons of the rat spinal cord
Q34951870Bilateral descending hypothalamic projections to the spinal trigeminal nucleus caudalis in rats.
Q90133279Cellular Mechanisms for Antinociception Produced by Oxytocin and Orexins in the Rat Spinal Lamina II-Comparison with Those of Other Endogenous Pain Modulators
Q41682930Developmental change and sexual difference in synaptic modulation produced by oxytocin in rat substantia gelatinosa neurons
Q64910434Effects of exogenous oxytocin and atosiban antagonist on GABA in different region of brain.
Q48192225Fluorescent Visualisation of Oxytocin in the Hypothalamo-neurohypophysial/-spinal Pathways After Chronic Inflammation in Oxytocin-Monomeric Red Fluorescent Protein 1 Transgenic Rats.
Q96135546Gentle stroking stimuli induce affiliative responsiveness to humans in male rats
Q35563616Intranasal Oxytocin Administration is Associated with Enhanced Endogenous Pain Inhibition and Reduced Negative Mood States
Q47902613Intranasal Oxytocin Attenuates Reactive and Ongoing, Chronic Pain in a Model of Mild Traumatic Brain Injury
Q36185945Intrathecal oxytocin inhibits visceromotor reflex and spinal neuronal responses to noxious distention of the rat urinary bladder
Q90283745Leptin and Associated Mediators of Immunometabolic Signaling: Novel Molecular Outcome Measures for Neurostimulation to Treat Chronic Pain
Q39331154Long-lasting spinal oxytocin analgesia is ensured by the stimulation of allopregnanolone synthesis which potentiates GABA(A) receptor-mediated synaptic inhibition.
Q90599533Molecular Mechanisms of Oxytocin Signaling at the Synaptic Connection
Q54558145Neurotensin inhibits background K+ channels and facilitates glutamatergic transmission in rat spinal cord dorsal horn.
Q26864853Oxytocin - a multifunctional analgesic for chronic deep tissue pain
Q90675081Oxytocin Relieves Neuropathic Pain Through GABA Release and Presynaptic TRPV1 Inhibition in Spinal Cord
Q47615009Oxytocin Signaling in Pain: Cellular, Circuit, System, and Behavioral Levels
Q42442561Oxytocin activates calcium signaling in rat sensory neurons through a protein kinase C-dependent mechanism
Q34257617Oxytocin and vasopressin agonists and antagonists as research tools and potential therapeutics
Q50616372Oxytocin down-regulates mesenteric afferent sensitivity via the enteric OTR/nNOS/NO/KATP pathway in rat.
Q28570992Oxytocin enhances cranial visceral afferent synaptic transmission to the solitary tract nucleus
Q36054711Oxytocin inhibits the membrane depolarization-induced increase in intracellular calcium in capsaicin sensitive sensory neurons: a peripheral mechanism of analgesic action
Q51742579Oxytocin produces thermal analgesia via vasopressin-1a receptor by modulating TRPV1 and potassium conductance in the dorsal root ganglion neurons.
Q59808581Oxytocin, GABA, and TRPV1, the Analgesic Triad?
Q33989258Oxytocin-induced analgesia and scratching are mediated by the vasopressin-1A receptor in the mouse
Q38472460Oxytocin: recent developments
Q24651638Oxytocin: the great facilitator of life.
Q64085129Pain, Parental Involvement, and Oxytocin in the Neonatal Intensive Care Unit
Q28468543Phase 1 safety assessment of intrathecal oxytocin
Q57818272Pituitary Hormones and Orofacial Pain
Q89134596Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury
Q48769838Possible Involvement of the Rat Hypothalamo-Neurohypophysial/-Spinal Oxytocinergic Pathways in Acute Nociceptive Responses.
Q33566397Preclinical toxicity screening of intrathecal oxytocin in rats and dogs
Q38833653Protocol for a placebo-controlled, within-participants crossover trial evaluating the efficacy of intranasal oxytocin to improve pain and function among women with chronic pelvic musculoskeletal pain
Q34275403REVIEW: Oxytocin: Crossing the bridge between basic science and pharmacotherapy
Q90084353Recurrent antinociception induced by intrathecal or peripheral oxytocin in a neuropathic pain rat model
Q54444763Synaptic modulation and inward current produced by oxytocin in substantia gelatinosa neurons of adult rat spinal cord slices.
Q35867587The Analgesic Effect of Oxytocin in Humans: A Double-Blind, Placebo-Controlled Cross-Over Study Using Laser-Evoked Potentials.
Q24288817The search for novel analgesics: targets and mechanisms
Q39345323Toward Understanding Myometrial Regulation: Metabolomic Investigation Reveals New Pathways of Oxytocin and Ritodrine Activity on the Myometrium.
Q34472905Visualization of oxytocin release that mediates paired pulse facilitation in hypothalamic pathways to brainstem autonomic neurons
Q88440115[Effect of oxytocin on human pain perception]

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