Overexpression of the transmembrane tyrosine phosphatase LAR activates the caspase pathway and induces apoptosis

scientific journal article

Overexpression of the transmembrane tyrosine phosphatase LAR activates the caspase pathway and induces apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0960-9822(98)70106-X
P698PubMed publication ID9501065

P2093author name stringJ. Yuan
Q. Yu
L. P. Weng
P2860cites workA new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigenQ24294578
Functional association between the insulin receptor and the transmembrane protein-tyrosine phosphatase LAR in intact cellsQ24312499
The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domainsQ24314450
Tight control of gene expression in mammalian cells by tetracycline-responsive promotersQ24564850
Disruption of epithelial cell-matrix interactions induces apoptosisQ24673611
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytesQ28237565
Mechanisms and Functions of Cell DeathQ28261655
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosisQ28292299
Focal adhesions, contractility, and signalingQ28299775
The transmembrane protein-tyrosine phosphatase LAR modulates signaling by multiple receptor tyrosine kinasesQ28569180
Apoptosis: molecular regulation of cell deathQ28611445
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3Q28645710
Integrins and signal transduction pathways: the road takenQ29547895
p53 is required for radiation-induced apoptosis in mouse thymocytesQ29620281
The Fas death factorQ29620461
A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.Q30468168
Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix.Q34418845
Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils.Q35882747
Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycleQ37659597
Molecular control of life and deathQ40444997
A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cellsQ40514473
Apoptosis in cancer therapy: crossing the thresholdQ40694262
Anchorage dependence, integrins, and apoptosisQ40754534
Oncogenes and cell deathQ40757516
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.Q40792572
Integrin transmembrane signaling and cytoskeletal controlQ40952551
Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.Q41126383
Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinaseQ41191845
Suppression of interleukin-1 beta-converting enzyme-mediated cell death by insulin-like growth factorQ41224724
Consequences of altered oncogene expression in rodent cellsQ41340906
Suppression of insulin receptor activation by overexpression of the protein-tyrosine phosphatase LAR in hepatoma cellsQ41343402
Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR.Q41370376
P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzymeQ41481455
mRNA expression of two transmembrane protein tyrosine phosphatases is modulated by growth factors and growth arrest in 3T3 fibroblastsQ42828518
High Efficiency DNA-Mediated Transformation of Primate CellsQ44901923
Three receptor-linked protein-tyrosine phosphatases are selectively expressed on central nervous system axons in the Drosophila embryoQ46305718
The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in DrosophilaQ47071521
Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cellsQ48729588
Two closely related receptor-type tyrosine phosphatases are differentially expressed during rat lung development.Q52206175
Thymocyte apoptosis induced by p53-dependent and independent pathways.Q54242475
Protein tyrosine phosphatase activities are involved in apoptotic cancer cell death induced by GL331, a new homolog of etoposideQ58886263
Protein tyrosine phosphatases and the control of cellular signaling responsesQ71475516
Apoptosis in hematopoietic cells is associated with an extensive decrease in cellular phosphotyrosine content that can be inhibited by the tyrosine phosphatase antagonist pervanadateQ71725709
Effect of tumor necrosis factor-alpha on the phosphorylation of tyrosine kinase receptors is associated with dynamic alterations in specific protein-tyrosine phosphatasesQ73029439
The control of cell death in the early chick embryo wing budQ73083555
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecttransmembrane proteinQ424204
apoptotic processQ14599311
overexpressionQ61643320
P304page(s)247–256
P577publication date1998-02-26
P1433published inCurrent BiologyQ1144851
P1476titleOverexpression of the transmembrane tyrosine phosphatase LAR activates the caspase pathway and induces apoptosis
P478volume8

Reverse relations

cites work (P2860)
Q73303504CREB is cleaved by caspases during neural cell apoptosis
Q36014016Clinical Outcome 3 Years After Autologous Chondrocyte Implantation Does Not Correlate With the Expression of a Predefined Gene Marker Set in Chondrocytes Prior to Implantation but Is Associated With Critical Signaling Pathways
Q28568792Dynamics of protein-tyrosine phosphatases in rat adipocytes
Q40721131Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes
Q58486019Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene
Q58214636Induction of p53 dependent apoptosis upon overexpression of a nuclear protein tyrosine phosphatase
Q54098831Inhibition of the transmembrane protein tyrosine phosphatase lar by 3S-peptide-I enhances insulin receptor phosphorylation in intact cells.
Q28216539Interaction with podocin facilitates nephrin signaling
Q28583005Leukocyte Antigen-Related Protein Tyrosine Phosphatase Receptor: A Small Ectodomain Isoform Functions as a Homophilic Ligand and Promotes Neurite Outgrowth
Q41502830Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosis
Q30486719Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases
Q27305161MicroRNA dysregulation in the spinal cord following traumatic injury
Q28611533Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling
Q43987364Normal breast epithelial cells induce p53-dependent apoptosis and p53-independent cell cycle arrest of breast cancer cells.
Q40683710Phosphorylation-dependent cleavage of p130cas in apoptotic rat-1 cells
Q39537954Protein tyrosine phosphatase alpha regulates cell detachment and cell death profiles induced by nitric oxide donors in the A431 human carcinoma cell line.
Q88532210RhoA activation in axotomy-induced neuronal death
Q35592121Role of CSPG receptor LAR phosphatase in restricting axon regeneration after CNS injury
Q50701604Selective expression of CSPG receptors PTPσ and LAR in poorly regenerating reticulospinal neurons of lamprey.
Q28144976Specific inhibition of FGF-induced MAPK activation by the receptor-like protein tyrosine phosphatase LAR
Q33193334Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas
Q28575842Targets of fibroblast growth factor 1 (FGF-1) and FGF-2 signaling involved in the invasive and tumorigenic behavior of carcinoma cells
Q42806069The carboxyl-terminal tyrosine residue of protein-tyrosine phosphatase alpha mediates association with focal adhesion plaques
Q36319815The cascade hypothesis of keratoconus
Q28141335The transmembrane protein tyrosine phosphatase RPTPsigma modulates signaling of the epidermal growth factor receptor in A431 cells
Q32159773Within the hemopoietic system, LAR phosphatase is a T cell lineage-specific adhesion receptor-like protein whose phosphatase activity appears dispensable for T cell development, repertoire selection and function

Search more.