Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation

scientific journal article

Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/CNCR.21978
P3181OpenCitations bibliographic resource ID1332952
P698PubMed publication ID16752412
P5875ResearchGate publication ID7031383

P50authorShafaat RabbaniQ77959450
P2093author name stringDavid Goltzman
Anil Potti
Kanishka Sircar
Armen Aprikian
Gaoping Chen
P2860cites workOsteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
RANK is essential for osteoclast and lymph node developmentQ24598872
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formationQ24681552
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesisQ28293009
Metastasis to bone: causes, consequences and therapeutic opportunitiesQ29614310
Cancer statistics, 2005Q29617572
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Metastatic patterns of prostate cancer: an autopsy study of 1,589 patientsQ33904020
Receptor activator of NF-kappaB ligand (RANKL) is expressed in chondroblastoma: possible involvement in osteoclastic giant cell recruitment.Q33919157
Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: diagnostic and prognostic implications.Q33979879
RANK-Fc: a therapeutic antagonist for RANK-L in myelomaQ35053943
Aberrant expression of DeltaNp73 in benign and malignant tumours of the prostate: correlation with Gleason scoreQ35588857
Prostate cancer bone metastases promote both osteolytic and osteoblastic activityQ35678564
Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysisQ35843398
Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications.Q38446601
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerinQ39116155
Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the boneQ39946634
Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo--a role in tumour cell survival?Q40374890
The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.Q40432075
Oral squamous cell carcinoma cells induce osteoclast differentiation by suppression of osteoprotegerin expression in osteoblastsQ40440785
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines.Q40772885
Osteoprotegerin and rank ligand expression in prostate cancerQ42502915
A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastasesQ44291815
Osteoprotegerin in prostate cancer bone metastasis.Q51531894
MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL.Q53856850
Expression of osteoprotegerin correlates with aggressiveness and poor prognosis of gastric carcinoma.Q54765911
In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cellsQ57001253
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cordQ73766127
Receptor activator of nuclear factor kappaB (RANK) is expressed as a late event during malignant progression in Barrett's metaplasiaQ73904964
Expression and somatic mutation on androgen receptor gene in prostate cancerQ78553788
Prognostic significance of serum osteoprotegerin levels in patients with bladder carcinomaQ80602463
The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograftQ81323685
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectprostate cancerQ181257
P304page(s)289-298
P577publication date2006-07-01
P1433published inCancerQ326041
P1476titleExpression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation
P478volume107