OspA-CD40 dyad: ligand-receptor interaction in the translocation of neuroinvasive Borrelia across the blood-brain barrier

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OspA-CD40 dyad: ligand-receptor interaction in the translocation of neuroinvasive Borrelia across the blood-brain barrier is …
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P6179Dimensions Publication ID1047187292
P356DOI10.1038/SREP00086
P932PMC publication ID3216572
P698PubMed publication ID22355605

P2093author name stringMichal Novak
Andrej Kovac
Mangesh Bhide
Patrik Mlynarcik
Rastislav Mucha
Elena Bencurova
Lucia Pulzova
Marian Madar
P2860cites workBorrelia burgdorferi, host-derived proteases, and the blood-brain barrierQ24557407
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Borrelia burgdorferi adhesins identified using in vivo phage displayQ33296896
Induction of host matrix metalloproteinases by Borrelia burgdorferi differs in human and murine lyme arthritisQ33559321
DbpA, but not OspA, is expressed by Borrelia burgdorferi during spirochetemia and is a target for protective antibodiesQ33767776
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A monoclonal antibody to OspA inhibits association of Borrelia burgdorferi with human endothelial cellsQ34523034
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Decorin-binding proteins A and B confer distinct mammalian cell type-specific attachment by Borrelia burgdorferi, the Lyme disease spirocheteQ35163595
Identification of an immunologically important hypervariable domain of major outer surface protein A of Borrelia burgdorferiQ35400449
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Outer surface lipoproteins of Borrelia burgdorferi activate vascular endothelium in vitro.Q35511753
CD14 mediates cross talk between mononuclear cells and fibroblasts for upregulation of matrix metalloproteinase 9 by Borrelia burgdorferiQ35913446
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The Urokinase Receptor Can Be Induced byBorrelia burgdorferithrough Receptors of the Innate Immune SystemQ36046670
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Adhesion of Borrelia garinii to neuronal cells is mediated by the interaction of OspA with proteoglycansQ40294483
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CD40 ligand stimulates proinflammatory cytokine production by human endothelial cellsQ42453856
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Borrelia burgdorferi and other bacterial products induce expression and release of the urokinase receptor (CD87).Q50117815
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Borrelia burgdorferi adherence and injury to undifferentiated and differentiated neural cells in vitro.Q55478322
Adherence of the Lyme disease spirochete to glial cells and cells of glial origin.Q55485133
Blood—Brain Barrier GenomicsQ57677396
CD40 activation induces p53-dependent vascular endothelial growth factor secretion in human multiple myeloma cellsQ64379194
Borrelia burgdorferi and other related spirochetes bind to galactocerebrosideQ68187581
Adaptation of the Lyme disease spirochaete to the mammalian host environment results in enhanced glycosaminoglycan and host cell bindingQ73042813
Borrelia burgdorferi induces matrix metalloproteinases by neural culturesQ73232819
CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expressionQ74310001
Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaquesQ77756578
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectbrainQ1073
blood–brain barrierQ221694
P304page(s)86
P577publication date2011-01-01
P1433published inScientific ReportsQ2261792
P1476titleOspA-CD40 dyad: ligand-receptor interaction in the translocation of neuroinvasive Borrelia across the blood-brain barrier
P478volume1