Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)

scientific journal article

Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm) is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.048777
P932PMC publication ID2804173
P698PubMed publication ID19858196
P5875ResearchGate publication ID38037527

P50authorManisha NautiyalQ65600769
P2093author name stringSusan M. Hutson
David T. Chuang
Mohammad Mainul Islam
James A. Mobley
R. Max Wynn
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Interaction of branched chain amino acids and keto acids upon pancreatic islet metabolism and insulin secretionQ72140508
Macromolecular interactions: tracing the rootsQ73493196
Branched-chain amino-acid aminotransferase of Escherichia coliQ74318111
Production of recombinant mammalian holo-E2 and E3 and reconstitution of functional branched-chain alpha-keto acid dehydrogenase complex with recombinant E1Q74318135
Mammalian branched-chain aminotransferasesQ74318160
A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complexQ79807582
Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membraneQ24556643
Application of a Theory of Enzyme Specificity to Protein SynthesisQ24620284
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulationQ27630686
The structure of human mitochondrial branched-chain aminotransferaseQ27630770
The structure of apo human glutamate dehydrogenase details subunit communication and allosteryQ27639129
Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate formsQ27639682
Structure-function relationships in dihydrolipoamide acyltransferasesQ28247047
Overexpression and characterization of the human mitochondrial and cytosolic branched-chain aminotransferasesQ28262954
Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysisQ28269148
Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase geneQ28269681
Regulation of mammalian pyruvate and branched-chain alpha-keto acid dehydrogenase complexes by phosphorylation-dephosphorylationQ28287050
Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cellQ28565418
Escherichia coli aromatic amino acid aminotransferase: characterization and comparison with aspartate aminotransferaseQ30421365
Identification of protein fragments as pattern features in MALDI-MS analyses of serumQ33224829
Folding funnels and binding mechanismsQ33743626
A trail of research from lipoic acid to alpha-keto acid dehydrogenase complexesQ33953799
A versatile conformational switch regulates reactivity in human branched-chain alpha-ketoacid dehydrogenaseQ33993506
Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase.Q34138951
Reversible compartmentalization of de novo purine biosynthetic complexes in living cellsQ34767701
Chapter 26 Preparation and Characterization of Mitochondria and Submitochondrial Particles of Rat Liver and Liver-Derived TissuesQ35760521
New insights into amino acid metabolism, beta-cell function and diabetesQ35950524
Alanine and inter-organ relationships in branched-chain amino and 2-oxo acid metabolism. ReviewQ39851055
Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretionQ39988003
Circular dichroism of complexes of NADH with self-associating bovine liver glutamate dehydrogenaseQ40284840
Unregulated insulin secretion by pancreatic beta cells in hyperinsulinism/hyperammonemia syndrome: role of glutamate dehydrogenase, ATP-sensitive potassium channel, and nonselective cation channelQ40313259
Distinguishing Features of Leucine and α-Ketoisocaproate Sensing in Pancreatic β-CellsQ40655102
Expression of E1 component of human branched-chain alpha-keto acid dehydrogenase complex in Escherichia coli by cotransformation with chaperonins GroEL and GroES.Q40855004
Role of the pleiotropic effects of plasminogen deficiency in infection experiments with plasminogen-deficient miceQ41479556
L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenaseQ41614642
Purification of branched chain aminotransferase from rat heart mitochondriaQ42631433
Ox glutamate dehydrogenase. Comparison of the kinetic properties of native and proteolysed preparationsQ42866212
Potential role of leucine metabolism in the leucine-signaling pathway involving mTOR.Q44482073
Branched-chain amino acid catabolism: unique segregation of pathway enzymes in organ systems and peripheral nervesQ44579245
Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzymeQ44925085
Reactive amino acid residues involved in glutamate-binding of human glutamate dehydrogenase isozymesQ44934128
Regulation of leucine and alpha-ketoisocaproate metabolism in skeletal muscleQ44987034
Uptake of individual amino acids by the human brainQ45070352
Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptationQ45143788
Identification of ADP-ribosylation site in human glutamate dehydrogenase isozymesQ46603315
A molecular model of human branched-chain amino acid metabolismQ46762438
Nonfibrinolytic functions of plasminogenQ47865721
Tissue heterogeneity of the mammalian mitochondrial proteomeQ48439191
Pyruvate carboxylaseQ48464317
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
P304page(s)265–276
P577publication date2010-01-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleBranched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)
P478volume285

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