TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing

scientific journal article

TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NN.3468
P3181OpenCitations bibliographic resource ID1922553
P932PMC publication ID4034143
P698PubMed publication ID23872594
P5875ResearchGate publication ID250924044

P50authorAllan BasbaumQ4730473
Tulip NuwalQ112640647
P2093author name stringYuh-Nung Jan
Bo Huang
Lily Yeh Jan
Fen Huang
Xidao Wang
Eric M. Ostertag
P2860cites workANOs 3–7 in the anoctamin/Tmem16 Cl− channel family are intracellular proteinsQ24296747
Anoctamins are a family of Ca2+-activated Cl- channelsQ24297964
Calcium-dependent phospholipid scrambling by TMEM16FQ24308774
TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminalsQ24314645
Superresolution imaging of chemical synapses in the brainQ24599389
Mutations in ANO3 cause dominant craniocervical dystonia: ion channel implicated in pathogenesisQ24602504
An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neuronsQ24810749
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesiaQ28144926
A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neuronsQ28215950
Molecular mechanisms of nociceptionQ28216291
International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channelsQ28289138
Ca2+-activated Cl− currents are dispensable for olfactionQ28505852
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neuronsQ28506470
TRPM8 is required for cold sensation in miceQ28509502
The sodium-activated potassium channel is encoded by a member of the Slo gene familyQ28570518
Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATPQ28574688
TMEM16A confers receptor-activated calcium-dependent chloride conductanceQ28590097
TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood CoagulationQ28590146
The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perceptionQ28591983
Cellular and Molecular Mechanisms of PainQ29011961
Studies on expression and function of the TMEM16A calcium-activated chloride channelQ30491820
Expanding the neuron's calcium signaling repertoire: intracellular calcium release via voltage-induced PLC and IP3R activationQ33277110
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studiesQ33277841
Expression cloning of TMEM16A as a calcium-activated chloride channel subunitQ33370813
Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neuronsQ34086296
External cadmium and internal calcium block of single calcium channels in smooth muscle cells from rabbit mesenteric arteryQ34125250
Data mining of high density genomic variant data for prediction of Alzheimer's disease riskQ34138248
Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons.Q34160850
Tackling Pain at the Source: New Ideas about NociceptorsQ34467545
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activityQ34821709
Conservation and evolution of gene coexpression networks in human and chimpanzee brainsQ35215128
Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampusQ35833781
Calcium-Activated Chloride Channels (CaCCs) Regulate Action Potential and Synaptic Response in Hippocampal NeuronsQ35898680
For K+ channels, Na+ is the new Ca2+.Q36175148
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contractionQ36342946
Effect of Na(+) flow on Cd(2+) block of tetrodotoxin-resistant Na(+) channels.Q36447163
Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neuronsQ36678533
Na+-mediated coupling between AMPA receptors and KNa channels shapes synaptic transmissionQ37081626
Na+-activated K+ channels express a large delayed outward current in neurons during normal physiologyQ37266972
Development in the STORMQ38067207
Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residueQ40404449
NAD+ activates KNa channels in dorsal root ganglion neurons.Q42452591
Amino-termini isoforms of the Slack K+ channel, regulated by alternative promoters, differentially modulate rhythmic firing and adaptationQ42597137
Restriction of Transient Receptor Potential Vanilloid-1 to the Peptidergic Subset of Primary Afferent Neurons Follows Its Developmental Downregulation in Nonpeptidergic NeuronsQ42848498
An electronic pressure-meter nociception paw test for ratsQ44827445
Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neuronsQ48250784
The presence and role of the tetrodotoxin-resistant sodium channel Na(v)1.9 (NaN) in nociceptive primary afferent neurons.Q49056592
Isolectin B(4)-positive and -negative nociceptors are functionally distinct.Q51449831
Electrophysiological differences between nociceptive and non-nociceptive dorsal root ganglion neurones in the rat in vivoQ60736394
Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunitsQ77299369
Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon systemQ80448597
Production of Endoribonuclease-Prepared Short Interfering RNAs (esiRNAs) for Specific and Effective Gene Silencing in Mammalian CellsQ83489629
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)1284–1290
P577publication date2013-09-01
P1433published inNature NeuroscienceQ1535359
P1476titleTMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing
P478volume16

Reverse relations

cites work (P2860)
Q28066190A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipid
Q30830965A novel ANO3 variant identified in a 53-year-old woman presenting with hyperkinetic dysarthria, blepharospasm, hyperkinesias, and complex motor tics
Q89964944ANO3 Mutations in Chinese Dystonia: A Genetic Screening Study Using Next-Generation Sequencing
Q47661281ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer.
Q50000586An ancestral TMEM16 homolog from Dictyostelium discoideum forms a scramblase
Q37593191Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity
Q92316393Anoctamin 3: A Possible Link between Cluster Headache and Ca2+ Signaling
Q28077344Cellular functions of TMEM16/anoctamin
Q55265914Chloride Homeostasis in Neurons With Special Emphasis on the Olivocerebellar System: Differential Roles for Transporters and Channels.
Q34572775Common variants associated with general and MMR vaccine-related febrile seizures
Q36949874Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+) channel
Q33958421Emerging role of the KCNT1 Slack channel in intellectual disability
Q27319989Epilepsy-Related Slack Channel Mutants Lead to Channel Over-Activity by Two Different Mechanisms
Q92257321Exposure to Ionizing Radiation Triggers Prolonged Changes in Circular RNA Abundance in the Embryonic Mouse Brain and Primary Neurons
Q64076570Haploinsufficiency of the brain-derived neurotrophic factor gene is associated with reduced pain sensitivity
Q34957755Human slack potassium channel mutations increase positive cooperativity between individual channels
Q41436986Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development
Q39166252International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels
Q36270776Knockout of Slo2.2 enhances itch, abolishes KNa current, and increases action potential firing frequency in DRG neurons
Q64938265Known structures and unknown mechanisms of TMEM16 scramblases and channels.
Q34506445Modulating Ca²⁺ signals: a common theme for TMEM16, Ist2, and TMC.
Q39102527Molecular, biophysical, and pharmacological properties of calcium-activated chloride channels.
Q37622078MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain
Q35555080Multiple transcripts of anoctamin genes expressed in the mouse submandibular salivary gland
Q64923978Nociceptor Signalling through ion Channel Regulation via GPCRs.
Q36238581Permeation Mechanisms in the TMEM16B Calcium-Activated Chloride Channels
Q42318144Profile of Lily and Yuh Nung Jan, winners of the 2017 Vilcek Prize in Biomedical Science
Q47689959Protein kinase A-induced internalization of Slack channels from the neuronal membrane occurs by adaptor protein-2/clathrin-mediated endocytosis
Q98188932Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes
Q36950726Recent advances in the genetics of dystonia
Q38182826Regulating excitability of peripheral afferents: emerging ion channel targets
Q42281905SLC26A11 (KBAT) in Purkinje Cells Is Critical for Inhibitory Transmission and Contributes to Locomotor Coordination
Q34339412SLO-2 potassium channel is an important regulator of neurotransmitter release in Caenorhabditis elegans
Q38915666Selective serotonin reuptake inhibitors facilitate ANO6 (TMEM16F) current activation and phosphatidylserine exposure
Q51015877Slack channels expressed in sensory neurons control neuropathic pain in mice
Q36586021Slack sodium-activated potassium channel membrane expression requires p38 mitogen-activated protein kinase phosphorylation
Q41700247Slick (Kcnt2) Sodium-Activated Potassium Channels Limit Peptidergic Nociceptor Excitability and Hyperalgesia
Q64116363Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice
Q26851981Structure and function of TMEM16 proteins (anoctamins)
Q34796577Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit
Q38275906TMEM16 proteins: unknown structure and confusing functions.
Q47686304TMEM16C cuts pain no SLACK.
Q28600840The BRAIN Initiative Provides a Unifying Context for Integrating Core STEM Competencies into a Neurobiology Course
Q42738774The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel
Q33739821Tumor necrosis factor α modulates sodium-activated potassium channel SLICK in rat dorsal horn neurons via p38 MAPK activation pathway
Q33840478[EXPRESS] Slack KNa Channels Influence Dorsal Horn Synapses and Nociceptive Behavior

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