| scholarly article | Q13442814 |
| P50 | author | Sarah A Tersey | Q49635805 |
| David L Morris | Q57003455 | ||
| P2093 | author name string | Raghavendra G Mirmira | |
| Bernhard Maier | |||
| Stephanie C Colvin | |||
| P2860 | cites work | Inhibition of HIV-1 replication in lymphocytes by mutants of the Rev cofactor eIF-5A | Q24321701 |
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| eIF5A has a function in the elongation step of translation in yeast | Q27934806 | ||
| Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen | Q28141785 | ||
| A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex | Q28257755 | ||
| Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors | Q28282381 | ||
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| Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model | Q30421540 | ||
| Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes | Q30429251 | ||
| The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice | Q30435990 | ||
| Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure | Q30438373 | ||
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| The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongation | Q33800179 | ||
| Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. | Q34244112 | ||
| Reversal of beta-cell suppression in vitro in pancreatic islets isolated from nonobese diabetic mice during the phase preceding insulin-dependent diabetes mellitus | Q34253666 | ||
| Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta | Q34514715 | ||
| Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease | Q34556560 | ||
| A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy | Q34949098 | ||
| Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes | Q35123531 | ||
| eIF5A interacts functionally with eEF2. | Q35632987 | ||
| How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited | Q35796906 | ||
| The non-obese diabetic (NOD) mouse | Q35856058 | ||
| ER stress as a trigger for β-cell dysfunction and autoimmunity in type 1 diabetes | Q35857760 | ||
| The NOD mouse: a model of immune dysregulation | Q36072434 | ||
| In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes | Q36399048 | ||
| A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells | Q36717967 | ||
| Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cells | Q36932559 | ||
| T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation | Q36973651 | ||
| Targeting regulatory T cells in the treatment of type 1 diabetes mellitus | Q37006155 | ||
| Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary B cells by EBV. | Q37092673 | ||
| Immune cell crosstalk in type 1 diabetes | Q37767586 | ||
| Hypusine: a new target for therapeutic intervention in diabetic inflammation | Q37776551 | ||
| The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis. | Q38074472 | ||
| Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. | Q40236795 | ||
| Independent roles of eIF5A and polyamines in cell proliferation. | Q40514139 | ||
| Mouse islet of Langerhans isolation using a combination of purified collagenase and neutral protease | Q41461963 | ||
| Inhibition of CD83 cell surface expression during dendritic cell maturation by interference with nuclear export of CD83 mRNA. | Q42972688 | ||
| First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes. | Q44253807 | ||
| Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines. | Q54191220 | ||
| Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes | Q57920468 | ||
| Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach | Q61872982 | ||
| Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. The Diabetes Control and Complications Trial Research Group | Q74366672 | ||
| Effects of autoimmunity and immune therapy on beta-cell turnover in type 1 diabetes | Q79386759 | ||
| Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group | Q84567639 | ||
| P433 | issue | 51 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | type-1 diabetes | Q124407 |
| Deoxyhypusine synthase | Q21984997 | ||
| P304 | page(s) | 36226-36235 | |
| P577 | publication date | 2013-11-06 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes | |
| P478 | volume | 288 |
| Q94421709 | Effect of Arginase-1 Inhibition on the Incidence of Autoimmune Diabetes in NOD Mice |
| Q90623365 | Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes |
| Q38747073 | Peroxisome Proliferator-activated Receptor-γ Activation Augments the β-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and β Cell Death in Non-obese Diabetic Mice |
| Q94526334 | Recent insights into eukaryotic translation initiation factors 5A1 and 5A2 and their roles in human health and disease |
| Q62867986 | Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder |
| Q61798209 | eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes |
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