BMPR2 is required for postimplantation uterine function and pregnancy maintenance

scientific article

BMPR2 is required for postimplantation uterine function and pregnancy maintenance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI65710
P932PMC publication ID3668851
P698PubMed publication ID23676498
P5875ResearchGate publication ID236911263

P50authorFrancesco J DeMayoQ62942908
John P. LydonQ90976640
P2093author name stringMartin M Matzuk
Qinglei Li
Takashi Nagashima
Caterina Clementi
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Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancyQ24676102
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesisQ28300359
A role for hematopoietic stem cells in promoting angiogenesisQ28508896
Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in miceQ28512780
BMP type II receptor is required for gastrulation and early development of mouse embryosQ28586233
Improved immunohistochemical method for detecting hypoxia gradients in mouse tissues and tumorsQ44901206
Risk factors for and perinatal mortality of abruptio placentae in patients hospitalised for early onset severe pre-eclampsia - a case controlled studyQ46144532
Generation of a floxed allele of the mouse BMP type II receptor gene.Q51535561
Decidual NK cells regulate key developmental processes at the human fetal-maternal interface.Q52010655
The uterine NK cell population requires IL-15 but these cells are not required for pregnancy nor the resolution of a Listeria monocytogenes infection.Q52103889
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertensionQ55670914
Unique Receptor Repertoire in Mouse Uterine NK cellsQ61437179
Late sporadic miscarriage is associated with abnormalities in spiral artery transformation and trophoblast invasionQ61842575
Assessment of Requirements for IL-15 and IFN Regulatory Factors in Uterine NK Cell Differentiation and Function During PregnancyQ61911905
Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitroQ67862177
Absence of natural killer cells during murine pregnancy is associated with reproductive compromise in TgE26 miceQ72995026
Subset classification of mouse uterine natural killer cells by DBA lectin reactivityQ73389370
Granzymes D, E, F, and G are regulated through pregnancy and by IL-2 and IL-15 in granulated metrial gland cellsQ77319228
Differential expression of VEGF isoforms and VEGF(164)-specific receptor neuropilin-1 in the mouse uterus suggests a role for VEGF(164) in vascular permeability and angiogenesis during implantationQ28592073
BMP signaling is required for septation of the outflow tract of the mammalian heartQ28592358
Interleukin-11 signaling is required for the differentiation of natural killer cells at the maternal-fetal interfaceQ28594669
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF geneQ29547732
Bone morphogenetic proteins: multifunctional regulators of vertebrate developmentQ29618986
Control of oocyte release by progesterone receptor-regulated gene expressionQ33595244
Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice.Q33685598
Subfertility linked to combined luteal insufficiency and uterine progesterone resistanceQ34132407
Endocannabinoid signaling directs differentiation of trophoblast cell lineages and placentationQ34165415
Comparative developmental anatomy of the murine and human definitive placentae.Q34546263
Hoxa-10 deficiency alters region-specific gene expression and perturbs differentiation of natural killer cells during decidualizationQ34698964
Deciphering the cross-talk of implantation: advances and challengesQ34699932
Genetic analysis of the mammalian transforming growth factor-beta superfamilyQ35017076
Evidence for coordinated interaction of cyclin D3 with p21 and cdk6 in directing the development of uterine stromal cell decidualization and polyploidy during implantationQ35067639
Endovascular trophoblast invasion: implications for the pathogenesis of intrauterine growth retardation and preeclampsiaQ35079406
Natural killer cells direct hemochorial placentation by regulating hypoxia-inducible factor dependent trophoblast lineage decisionsQ35239994
Invasion of the trophoblastsQ35476692
The bone morphogenetic protein system in mammalian reproductionQ35652692
Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wallQ35787199
Bmp2 is critical for the murine uterine decidual responseQ35950036
Degradation of extracellular matrix by mouse trophoblast outgrowths: a model for implantationQ36206813
The involvement of interleukin (IL)-15 in regulating the differentiation of granulated metrial gland cells in mouse pregnant uterusQ36377440
Engraftment of bone marrow from severe combined immunodeficient (SCID) mice reverses the reproductive deficits in natural killer cell-deficient tg epsilon 26 miceQ36400163
The uterine spiral arteries in human pregnancy: facts and controversiesQ36401771
Imaging of vascular development in early mouse decidua and its association with leukocytes and trophoblasts.Q36433107
Maternal hypoxia activates endovascular trophoblast cell invasionQ36494058
Blastocyst's state of activity determines the "window" of implantation in the receptive mouse uterusQ36636796
The biology of infertility: research advances and clinical challengesQ37206451
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.Q37298556
Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie systemQ37398561
Oxygen homeostasisQ37788021
The postimplantation embryo differentially regulates endometrial gene expression and decidualizationQ38301669
Cre-mediated recombination in cell lineages that express the progesterone receptorQ38521008
Uterine cell death during implantation and early placentationQ40859916
Decidual spiral artery remodeling during early post-implantation period in mice: investigation of associations with decidual uNK cells and invasive trophoblastQ43659230
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.Q44166149
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectBone morphogenetic protein receptor, type II (serine/threonine kinase)Q21495412
P304page(s)2539-2550
P577publication date2013-05-08
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleBMPR2 is required for postimplantation uterine function and pregnancy maintenance
P478volume123

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