N-acetylaspartylglutamate synthetase II synthesizes N-acetylaspartylglutamylglutamate

scientific journal article

N-acetylaspartylglutamate synthetase II synthesizes N-acetylaspartylglutamylglutamate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.230136
P932PMC publication ID3089511
P698PubMed publication ID21454531

P2093author name stringVolkmar Gieselmann
Matthias Eckhardt
Lihua Wang-Eckhardt
Ivonne Becker
Julia Lodder-Gadaczek
P2860cites workHigh-efficiency transformation of mammalian cells by plasmid DNAQ27860469
N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous systemQ28141091
DISTRIBUTION OF N-ACETYL-ASPARTIC AND N-ACETYL-ASPARTYL-GLUTAMIC ACIDS IN NERVOUS TISSUEQ28202499
Canavan disease and the role of N-acetylaspartate in myelin synthesisQ28237204
The nagging question of the function of N-acetylaspartylglutamateQ28253973
The neurotransmitter N-acetylaspartylglutamate in models of pain, ALS, diabetic neuropathy, CNS injury and schizophreniaQ28264674
Mice lacking glutamate carboxypeptidase II are protected from peripheral neuropathy and ischemic brain injuryQ28274467
Biosynthesis of NAAG by an enzyme-mediated process in rat central nervous system neurons and gliaQ28275162
Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthaseQ28506479
Molecular characterization of N-acetylaspartylglutamate synthetaseQ28592468
N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiologyQ33271816
A novel key-lock mechanism for inactivating amino acid neurotransmitters during transit across extracellular spaceQ33346614
Functions of N-acetyl-L-aspartate and N-acetyl-L-aspartylglutamate in the vertebrate brain: role in glial cell-specific signalingQ33971691
Elevated CSF N-acetylaspartylglutamate suggests specific molecular diagnostic abnormalities in patients with white matter diseases.Q34143204
Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2.Q34694983
Elevated CSF N-acetylaspartylglutamate in patients with free sialic acid storage diseasesQ35065452
Search for Drosophila genes encoding a conserved domain present in the achaete-scute complex and myc proteinsQ35194498
Identity of the high-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporterQ36520510
N-acetylaspartylglutamate: an endogenous peptide with high affinity for a brain "glutamate" receptorQ37604286
Evidence that the tri-cellular metabolism of N-acetylaspartate functions as the brain's "operating system": how NAA metabolism supports meaningful intercellular frequency-encoded communicationsQ37766474
Binding of Clostridium botulinum C2 toxin to asparagine-linked complex and hybrid carbohydratesQ38316315
beta-Citryl-L-glutamate is an endogenous iron chelator that occurs naturally in the developing brainQ42164794
N-Acetyl-<i>L</i>-Aspartate is a Major Source of Acetyl Groups for Lipid Synthesis during Rat Brain DevelopmentQ43802553
NAAG fails to antagonize synaptic and extrasynaptic NMDA receptors in cerebellar granule neurons.Q44771363
Severe hypomyelination associated with increased levels of N-acetylaspartylglutamate in CSF.Q44891231
Developmental Changes of N‐Acetyl‐L‐Aspartic Acid, N‐Acetyl‐α‐Aspartylglutamic Acid and β‐Citryl‐L‐Glutamic Acid in Different Brain Regions and Spinal Cords of Rat and Guinea PigQ46823484
Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cellsQ47930736
Evidence for the presence of N-acetylaspartylglutamate in cultured oligodendrocytes and LPS activated microgliaQ47962647
Localization and transport of N-acetylaspartylglutamate in cells of whole murine brain in primary cultureQ48298959
N-acetylaspartylglutamate (NAAG) in Pelizaeus-Merzbacher diseaseQ48486537
Expression of N-acetylaspartate and N-acetylaspartylglutamate in the nervous systemQ48486607
N-acetyl-aspartyl-glutamate: regional levels in rat brain and the effects of brain lesions as determined by a new HPLC methodQ48617777
N-acetylaspartylglutamate acts as an agonist upon homomeric NMDA receptor (NMDAR1) expressed in Xenopus oocytesQ49162797
Characterization of the gene rimK responsible for the addition of glutamic acid residues to the C-terminus of ribosomal protein S6 in Escherichia coli K12.Q54729391
Neurochemical and immunocytochemical studies on the distribution of N-acetyl-aspartylglutamate and N-acetyl-aspartate in rat spinal cord and some peripheral nervous tissuesQ68929555
Glutamate and N-acetylaspartylglutamate block HVA calcium currents in frog olfactory bulb interneurons via an mGluR2/3-like receptorQ71723539
N-acetylaspartylglutamate selectively inhibits neuronal responses to N-methyl-D-aspartic acid in vitroQ72109124
Comparative distribution of N-acetylaspartylglutamate and GAD67 in the cerebellum and precerebellar nuclei of the rat utilizing enhanced carbodiimide fixation and immunohistochemistryQ72392525
Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injuryQ73226156
N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cellsQ73456893
Increased level of N-acetylaspartylglutamate (NAAG) in the CSF of a patient with Pelizaeus-Merzbacher-like disease due to mutation in the GJA12 geneQ81324072
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectRibosomal modification protein rimK-like family member AQ21986700
Ac-Asp-Glu-Glu(4-)Q27146449
P304page(s)16693–16706
P577publication date2011-05-13
P1433published inJournal of Biological ChemistryQ867727
P1476titleN-acetylaspartylglutamate synthetase II synthesizes N-acetylaspartylglutamylglutamate
P478volume286

Reverse relations

cites work (P2860)
Q36381928ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs
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Q40382537N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time.
Q38833017N-acetylaspartylglutamate is an agonist at mGluR₃ in vivo and in vitro
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Q38831232The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological disease
Q44954480Vesicular uptake of N-acetylaspartylglutamate is catalysed by sialin (SLC17A5).