| scholarly article | Q13442814 |
| P2093 | author name string | Ya-Ping Jiang | |
| Kathleen G. Dickman | |||
| Lisa M. Ballou | |||
| Richard Z. Lin | |||
| Victoria L. B. Nelson | |||
| P2860 | cites work | General and Abdominal Adiposity and Risk of Death in Europe | Q22250882 |
| Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts | Q22253167 | ||
| Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator | Q24294798 | ||
| Twice upon a time: PI3K's secret double life exposed | Q24317406 | ||
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Q24599676 | ||
| Determination of lipolysis in isolated primary adipocytes | Q46564244 | ||
| Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro | Q46735523 | ||
| Loss of class IA PI3K signaling in muscle leads to impaired muscle growth, insulin response, and hyperlipidemia. | Q51498542 | ||
| Rotavirus alters paracellular permeability and energy metabolism in Caco-2 cells. | Q52541093 | ||
| Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone. | Q53572340 | ||
| Leptin: a review of its peripheral actions and interactions | Q56169405 | ||
| Expression of the thermogenic nuclear hormone receptor coactivator PGC-1α is reduced in the adipose tissue of morbidly obese subjects | Q58035875 | ||
| Impaired glucose transport and protein kinase B activation by insulin, but not okadaic acid, in adipocytes from subjects with Type II diabetes mellitus | Q59466729 | ||
| Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin | Q72237918 | ||
| Diabetes, a New Mutation in the Mouse | Q72798788 | ||
| Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction | Q74191142 | ||
| A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance | Q77652485 | ||
| Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes | Q78785297 | ||
| Studies of thermogenesis and mitochondrial function in adipose tissues | Q81369840 | ||
| Identification and importance of brown adipose tissue in adult humans | Q24632425 | ||
| Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 | Q24679555 | ||
| Synthesis and function of 3-phosphorylated inositol lipids | Q28200755 | ||
| PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth | Q28243336 | ||
| Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese | Q28510931 | ||
| UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality | Q28513102 | ||
| Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation | Q28594707 | ||
| PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes | Q29547229 | ||
| Brown adipose tissue: function and physiological significance | Q29547448 | ||
| Critical nodes in signalling pathways: insights into insulin action | Q29614735 | ||
| Insulin and insulin-like growth factor-1 receptors act as ligand-specific amplitude modulators of a common pathway regulating gene transcription | Q33883451 | ||
| Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance | Q34137882 | ||
| The Identification of the Component in the Inner Membrane of Brown Adipose Tissue Mitochondria Responsible for Regulating Energy Dissipation | Q34180502 | ||
| Insulin- and leptin-regulated fatty acid uptake plays a key causal role in hepatic steatosis in mice with intact leptin signaling but not in ob/ob or db/db mice | Q34212126 | ||
| Development of obesity in transgenic mice after genetic ablation of brown adipose tissue | Q34346636 | ||
| Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. | Q34570264 | ||
| Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments | Q34630211 | ||
| Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation | Q35131032 | ||
| Energy Expenditure and Fuel Selection in Biological Systems: The Theory and Practice of Calculations Based on Indirect Calorimetry and Tracer Methods | Q35201226 | ||
| Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis | Q35796978 | ||
| The acute effects of leptin require PI3K signaling in the hypothalamic ventral premammillary nucleus | Q35870445 | ||
| Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus | Q36111074 | ||
| Cytochrome c oxidase dysfunction in oxidative stress | Q36218389 | ||
| Hypothalamic phosphatidylinositol 3-kinase pathway of leptin signaling is impaired during the development of diet-induced obesity in FVB/N mice | Q36509764 | ||
| Lessons on conditional gene targeting in mouse adipose tissue | Q36635274 | ||
| Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor | Q37161010 | ||
| Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development | Q37223903 | ||
| Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction | Q37324188 | ||
| Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis | Q37360125 | ||
| Nonshivering thermogenesis and its adequate measurement in metabolic studies | Q37823045 | ||
| Mitochondria are impaired in the adipocytes of type 2 diabetic mice | Q38315463 | ||
| PI3K/AKT signaling regulates bioenergetics in immortalized hepatocytes | Q40705320 | ||
| Dual regulation of glycogen synthase kinase-3beta by the alpha1A-adrenergic receptor | Q40782689 | ||
| PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis | Q41957703 | ||
| Thermogenic responses in brown fat cells are fully UCP1-dependent. UCP2 or UCP3 do not substitute for UCP1 in adrenergically or fatty scid-induced thermogenesis | Q42488444 | ||
| Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt. | Q42820035 | ||
| Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons | Q42937219 | ||
| P433 | issue | 10 | |
| P921 | main subject | obesity | Q12174 |
| insulin resistance | Q1053470 | ||
| preproinsulin | Q7240673 | ||
| Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Q14887711 | ||
| P304 | page(s) | E1205–1216 | |
| P577 | publication date | 2014-05-15 | |
| P1433 | published in | American Journal of Physiology - Endocrinology and Metabolism | Q15765671 |
| P1476 | title | Adipose tissue insulin resistance due to loss of PI3K p110α leads to decreased energy expenditure and obesity | |
| P478 | volume | 306 |
| Q48482776 | Activation of PPAR-γ reduces HPA axis activity in diabetic rats by up-regulating PI3K expression |
| Q50068190 | Brown and Beige Adipose Tissues in Health and Disease. |
| Q89576047 | Calorie Restriction-Induced Increase in Skeletal Muscle Insulin Sensitivity Is Not Prevented by Overexpression of the p55α Subunit of Phosphoinositide 3-Kinase |
| Q35834778 | Energy balancing by fat Pik3ca |
| Q64077342 | Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue |
| Q90289927 | Ethanol-Induced Hepatic Insulin Resistance is Ameliorated by Methyl Ferulic Acid Through the PI3K/AKT Signaling Pathway |
| Q99248451 | Hyperinsulinaemia in cancer |
| Q89882441 | Increased mitochondrial and lipid metabolism is a conserved effect of Insulin/PI3K pathway downregulation in adipose tissue |
| Q30365903 | Kisspeptin cell-specific PI3K signaling regulates hypothalamic kisspeptin expression and participates in the regulation of female fertility. |
| Q37710206 | Loss of PI3K p110α in the Adipose Tissue Results in Infertility and Delayed Puberty Onset in Male Mice. |
| Q58695348 | PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice |
| Q51005062 | Potent therapeutic effects of shouwu jiangqi decoction on polycystic ovary syndrome with insulin resistance in rats. |
| Q92295997 | Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism |
| Q33640546 | SHORT syndrome in a two-year-old girl - case report. |
| Q58767647 | Sericin enhances the insulin-PI3K/AKT signaling pathway in the liver of a type 2 diabetes rat model |
| Q92524549 | Specific knockout of p85α in brown adipose tissue induces resistance to high-fat diet-induced obesity and its metabolic complications in male mice |
| Q90589420 | The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells |
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