Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis

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Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PMED.1001961
P932PMC publication ID4755617
P698PubMed publication ID26881778
P5875ResearchGate publication ID295097463

P50authorRachael NatrajanQ30582887
Mitch DowsettQ53099690
Yinyin YuanQ60664084
Chris BakalQ60665055
Faraz Khosravi MardakhehQ38304831
Christopher J TapeQ42564944
P2093author name stringHeba Sailem
Mar Arias Garcia
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
Mutational signatures: the patterns of somatic mutations hidden in cancer genomesQ26850125
Links between mutant p53 and genomic instabilityQ26864033
Genomic instability--an evolving hallmark of cancerQ28274009
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-upQ28306437
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroupsQ29614700
Supervised risk predictor of breast cancer based on intrinsic subtypesQ29617404
Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosisQ30004190
Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalizationQ30579125
Emergent behaviors from a cellular automaton model for invasive tumor growth in heterogeneous microenvironmentsQ31044416
Stromal gene expression predicts clinical outcome in breast cancerQ33330931
Systematic analysis of breast cancer morphology uncovers stromal features associated with survival.Q50994600
Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.Q51928042
Evaluation of a tumor microenvironment-based prognostic score in primary operable colorectal cancer.Q53246994
Prognostic Significance of Nottingham Histologic Grade in Invasive Breast CarcinomaQ64018963
Diagnostic and therapeutic implications of tumor-infiltrating lymphocytes in breast cancerQ85938442
A unified approach to false discovery rate estimationQ33350399
Solving the puzzle of metastasis: the evolution of cell migration in neoplasmsQ33351178
Tumor reversion: Correction of malignant behavior by microenvironmental cuesQ34103266
Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneityQ34287934
Genetic clonal diversity predicts progression to esophageal adenocarcinomaQ34505745
Prospective validation of immunological infiltrate for prediction of response to neoadjuvant chemotherapy in HER2-negative breast cancer--a substudy of the neoadjuvant GeparQuinto trialQ35060987
Subclonal diversification of primary breast cancer revealed by multiregion sequencingQ35847434
Ecological therapy for cancer: defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatmentsQ36970516
Co-evolution of tumor cells and their microenvironmentQ37340741
APOBEC3B is an enzymatic source of mutation in breast cancer.Q37533713
The prognostic significance of tumour-stroma ratio in oestrogen receptor-positive breast cancerQ37681755
Stromal contribution to the colorectal cancer transcriptome.Q38906913
The immune score as a new possible approach for the classification of cancerQ42539190
Prognostic significance of the tumor-stroma ratio: validation study in node-negative premenopausal breast cancer patients from the EORTC perioperative chemotherapy (POP) trial (10854).Q43475965
Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trialQ43951696
Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profilingQ44071623
Stromal gene expression defines poor-prognosis subtypes in colorectal cancerQ48222476
The mathematical theory of communication. 1963.Q48828107
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectheterogeneityQ928498
P304page(s)e1001961
P577publication date2016-02-16
P1433published inPLOS MEDICINEQ1686921
P1476titleMicroenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis
P478volume13

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cites work (P2860)
Q42378921A novel machine learning approach reveals latent vascular phenotypes predictive of renal cancer outcome.
Q36050577Antigenic variability: Obstacles on the road to vaccines against traditionally difficult targets
Q38656112Breast cancer complexity: implications of intratumoral heterogeneity in clinical management
Q42652763Breast-Lesion Characterization using Textural Features of Quantitative Ultrasound Parametric Maps
Q33721222Cancer heterogeneity is not compatible with one unique cancer cell metabolic map
Q91892149Computational analysis of pathological images enables a better diagnosis of TFE3 Xp11.2 translocation renal cell carcinoma
Q38847989Contemporary and potential future molecular diagnosis of melanoma.
Q91684519Digital pathology and artificial intelligence
Q47397566Effect of exosome biomarkers for diagnosis and prognosis of breast cancer patients
Q89128693Expression of Genes for Methylxanthine Pathway-Associated Enzymes Accompanied by Sex Steroid Receptor Status Impacts Breast Carcinoma Progression
Q47956086GK-1 peptide reduces tumor growth, decreases metastatic burden, and increases survival in a murine breast cancer model
Q50107042Genetic insights into the morass of metastatic heterogeneity.
Q38910371Homeostasis Back and Forth: An Ecoevolutionary Perspective of Cancer
Q63547036Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes
Q39045171Implementation of a Precision Pathology Program Focused on Oncology-Based Prognostic and Predictive Outcomes.
Q57159647Intratumoral Heterogeneity in Ductal Carcinoma In Situ: Chaos and Consequence
Q51415592Microenvironment-Cell Nucleus Relationship in the Context of Oxidative Stress.
Q54979633Microenvironmental Signals and Biochemical Information Processing: Cooperative Determinants of Intratumoral Plasticity and Heterogeneity.
Q47315881Modulating secreted components of tumor microenvironment: A masterstroke in tumor therapeutics.
Q92287304Quantitative MRI Biomarkers of Stereotactic Radiotherapy Outcome in Brain Metastasis
Q94927801Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group
Q37687582Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer
Q49922621Simulated ablation for detection of cells impacting paracrine signalling in histology analysis
Q37665209Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer.
Q50122934The perilous path from publication to practice.
Q48103743The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis
Q61796820Three-dimensional alteration of neurites in schizophrenia
Q90633042Tumor Drug Distribution after Local Drug Delivery by Hyperthermia, In Vivo

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