Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics

scientific journal article

Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/01.ATV.13.5.720
P698PubMed publication ID8485124

P50authorPhilip W ConnellyQ59392339
P2093author name stringG F Maguire
J A Little
C Vezina
R A Hegele
D J Jenkins
L Tu
T S Wolever
P433issue5
P304page(s)720-728
P577publication date1993-05-01
P1433published inArteriosclerosis and thrombosis : a journal of vascular biologyQ27709770
P1476titleHepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics
P478volume13

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cites work (P2860)
Q88352529A new enzyme-linked immunosorbent assay system for human serum hepatic triglyceride lipase
Q44168278A novel allele in the promoter of the hepatic lipase is associated with increased concentration of HDL-C and decreased promoter activity
Q22009153A novel endothelial-derived lipase that modulates HDL metabolism
Q36727383A novel method for measuring human lipoprotein lipase and hepatic lipase activities in postheparin plasma
Q72992423Absence of association between genetic variation in the LIPC gene promoter and plasma lipoproteins in three Canadian populations
Q37378483Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene. The LOCAT Study Invsestigators
Q33688098Atheroprotective mechanisms of HDL.
Q36708030Biochemistry and pathophysiology of intravascular and intracellular lipolysis
Q44460221Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians
Q47739431Characterization of two HDL subfractions and LpA-I, LpA-I:A-II distribution profiles and clinical characteristics of hyperalphalipoproteinemic subjects without cholesterol ester transfer protein deficiency
Q46020676Chinese hamster ovary cells expressing a cell surface-anchored form of hepatic lipase. Characterization of low density lipoprotein and chylomicron remnant uptake and selective uptake of high density lipoprotein-cholesteryl ester.
Q34155049Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport
Q31132390Comparative analyses of lipoprotein lipase, hepatic lipase, and endothelial lipase, and their binding properties with known inhibitors
Q33833805Decreases in the serum VLDL-TG/non-VLDL-TG ratio from early stages of chronic hepatitis C: alterations in TG-rich lipoprotein levels
Q44021015Deficiency in sPLA(2) does not affect HDL levels or atherosclerosis in mice
Q73575756Detection of missense mutations in the genes for lipoprotein lipase and hepatic triglyceride lipase in patients with dyslipidemia undergoing coronary angiography
Q74057286Dietary fat clearance in type V hyperlipoproteinaemia secondary to a rare variant of human apolipoprotein E: the apolipoprotein E3 (Arg 136-->Ser)
Q70785781Electrophoretic screening for human apolipoprotein C-II variants: repeated identification of apolipoprotein C-II(K19T)
Q34830395Endothelial lipase: direct evidence for a role in HDL metabolism
Q44919539Evidence that hepatic lipase deficiency in humans is not associated with proatherogenic changes in HDL composition and metabolism
Q33858537Expression of human hepatic lipase negatively impacts apolipoprotein A-I production in primary hepatocytes from Lipc-null mice.
Q40674487Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in HepG2 cells
Q41465066Gene therapy for atherosclerosis
Q34107177Gene therapy for dyslipidemia: clinical prospects
Q33877037Genes influencing HDL metabolism: new perspectives and implications for atherosclerosis prevention
Q33993060Genetic causes of high and low serum HDL-cholesterol
Q34651427Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol
Q38630971HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology
Q46866176HDL--is it too big to fail?
Q47962063Hepatic lipase affects both HDL and ApoB-containing lipoprotein levels in the mouse
Q35086127Hepatic lipase and dyslipidemia: interactions among genetic variants, obesity, gender, and diet
Q34756336Hepatic lipase deficiency.
Q37351772Hepatic lipase gene therapy in hepatic lipase-deficient mice. Adenovirus-mediated replacement of a lipolytic enzyme to the vascular endothelium
Q28581153Hepatic lipase is localized at the parenchymal cell microvilli in rat liver
Q77714408Hepatic lipase mediates an increase in selective uptake of high-density lipoprotein-associated cholesteryl esters by human Hep 3B hepatoma cells in culture
Q38303206Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor
Q28626701Hepatic lipase: high-level expression and subunit structure determination
Q73111097Heterozygous hepatic lipase deficiency, due to two missense mutations R186H and L334F, in the HL gene
Q45870343High-density lipoprotein metabolism and reverse cholesterol transport: strategies for raising HDL cholesterol
Q34107511High-density lipoprotein metabolism: molecular targets for new therapies for atherosclerosis
Q39442094High-density lipoprotein subpopulation profiles in lipoprotein lipase and hepatic lipase deficiency.
Q34990624High-density lipoproteins and atherosclerosis
Q57428565Higher order lipase gene association with plasma triglycerides
Q35062402Hugh sinclair lecture: the regulation and remodelling of HDL by plasma factors
Q35824669Human ApoA-II inhibits the hydrolysis of HDL triglyceride and the decrease of HDL size induced by hypertriglyceridemia and cholesteryl ester transfer protein in transgenic mice
Q36503521Human genetics of variation in high-density lipoprotein cholesterol
Q41168114Human hepatic lipase subunit structure determination
Q38235600Hyperlipoproteinemia type 3: the forgotten phenotype
Q42989672Identification of a heparin-releasable hepatic lipase binding protein from rat liver
Q51566083In vitro production of beta-very low density lipoproteins and small, dense low density lipoproteins in mildly hypertriglyceridemic plasma: role of activities of lecithin:cholester acyltransferase, cholesterylester transfer proteins and lipoprotein l
Q40579349Insulin and lipoprotein metabolism with special reference to the diabetic state
Q46452061Interactions between hepatic lipase and apolipoprotein E gene polymorphisms affect serum lipid profiles of healthy Canadian adults
Q50299754LIPC dimer hydrolyses TAG to DAG and FA
Q35784094Lipase maturation factor 1: a lipase chaperone involved in lipid metabolism
Q34594298Lipases and HDL metabolism
Q36493893Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.
Q33904125Mechanisms of lipase maturation
Q34040090Molecular mechanisms, lipoprotein abnormalities and atherogenicity of hyperalphalipoproteinemia
Q28363810Monogenic dyslipidemias: window on determinants of plasma lipoprotein metabolism
Q34707630No prescription for despair
Q35743918Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins
Q47121697Polygenic determinants in extremes of high-density lipoprotein cholesterol
Q43913020Polymorphism of HL +1075C, but not -480T, is associated with plasma high density lipoprotein cholesterol and apolipoprotein AI in men of a Chinese population
Q33577888Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population
Q35576667Positive association of the hepatic lipase gene polymorphism c.514C > T with estrogen replacement therapy response
Q90464954Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement
Q33597635Receptor-mediated mechanisms of lipoprotein remnant catabolism
Q35249345Recessive inheritance of obesity in familial non-insulin-dependent diabetes mellitus, and lack of linkage to nine candidate genes
Q44774939Reciprocal hemizygosity analysis of mouse hepatic lipase reveals influence on obesity
Q35212558Regulation of reverse cholesterol transport and clinical implications
Q36300834Reverse cholesterol transport and cholesterol efflux in atherosclerosis
Q40875893Reverse cholesterol transport--a review of the process and its clinical implications
Q33652033Role of fibrates in the management of hypertriglyceridemia
Q34901554Role of hepatic lipase and endothelial lipase in high-density lipoprotein-mediated reverse cholesterol transport
Q71371400Sandwich immunoassay for measurement of human hepatic lipase
Q39614897Secretion of triacylglycerol-poor VLDL particles from McA-RH7777 cells expressing human hepatic lipase
Q45005915Severe hypoalphalipoproteinemia in mice expressing human hepatic lipase deficient in binding to heparan sulfate proteoglycan.
Q51565747The atherogenic significance of an elevated plasma triglyceride level.
Q40964824The genetic determinants of plasma cholesterol and response to diet
Q37167521The independent relationship between triglycerides and coronary heart disease.
Q33746682The role of hepatic lipase in lipoprotein metabolism.
Q53528346The two novel CETP mutations Gln87X and Gln165X in a compound heterozygous state are associated with marked hyperalphalipoproteinemia and absence of significant coronary artery disease.
Q35824568Variation at the hepatic lipase and apolipoprotein AI/CIII/AIV loci is a major cause of genetically determined variation in plasma HDL cholesterol levels
Q24802147Genetic study of common variants at the Apo E, Apo AI, Apo CIII, Apo B, lipoprotein lipase (LPL) and hepatic lipase (LIPC) genes and coronary artery disease (CAD): variation in LIPC gene associates with clinical outcomes in patients with established

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