VLA-4-fibronectin interaction is required for the terminal differentiation of human bone marrow cells capable of spontaneous and high rate immunoglobulin secretion

scientific article published on June 1, 1992

VLA-4-fibronectin interaction is required for the terminal differentiation of human bone marrow cells capable of spontaneous and high rate immunoglobulin secretion is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.175.6.1739
P953full work available at URLhttps://europepmc.org/articles/PMC2119256
https://europepmc.org/articles/PMC2119256?pdf=render
P932PMC publication ID2119256
P698PubMed publication ID1588291
P5875ResearchGate publication ID276951750

P50authorAngeles Garcia PardoQ42635889
P2093author name stringJ. A. Brieva
E. Roldán
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Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA-4. Correlation with distinct alpha 4 epitopesQ41679955
Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1.Q41748075
The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cellsQ41867235
Extracellular matrix receptors, ECMRII and ECMRI, for collagen and fibronectin correspond to VLA-2 and VLA-3 in the VLA family of heterodimersQ42100673
Primary structure of human plasma fibronectin. Characterization of a 38 kDa domain containing the C-terminal heparin-binding site (Hep III site) and a region of molecular heterogeneityQ42134618
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytesQ42820082
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IL-2 dependence of the promotion of human B cell differentiation by IL-6 (BSF-2).Q43665213
Regulated expression and binding of three VLA (beta 1) integrin receptors on T cellsQ43680073
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Costimulation of proliferative responses of resting CD4+ T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with lamininQ44503153
Limiting dilution analysis of the B cell compartment in human bone marrowQ44560005
Lymphocyte function in human bone marrow. III. Isotype commitment, metabolic and secretory characteristics of immunoglobulin producing cellsQ45103058
The mechanism of thymus-dependent antibody formation in bone marrowQ46150459
Probing molecular polymorphism of fibronectins with antibodies directed to the alternatively spliced peptide segmentsQ46352195
Interleukin 6 is essential for antibody secretion by human in vivo antigen-induced lymphoblastoid B cellsQ46444646
Immunoglobulin synthesis by human lymphoid tissues: normal bone marrow as a major site of IgG productionQ48025875
Requirement for accessory cells in the antibody response to T cell-independent antigensin vitroQ50228030
Fibronectin promotes proliferation of naive and memory T cells by signaling through both the VLA-4 and VLA-5 integrin moleculesQ52107022
Population dynamics of bone marrow B lymphocytes.Q52137369
Human placental (fetal) fibronectin: increased glycosylation and higher protease resistance than plasma fibronectin. Presence of polylactosamine glycopeptides and properties of a 44-kilodalton chymotryptic collagen-binding domain: difference from huQ54477435
Differential expression of VLA-4 integrin by resident and peripheral blood B lymphocytes. Acquisition of functionally active α4β1-fibronectin receptors upon B cell activationQ58064819
VLA-3: a novel polypeptide association within the VLA molecular complex: cell distribution and biochemical characterizationQ58065014
Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell linesQ58065088
Long-term culture of human bone marrow. I. characterization of adherent cells in flow cytometryQ67658733
Human natural killer cells express different integrins and spread on fibronectinQ67687476
Terminal differentiation of human bone marrow cells capable of spontaneous and high-rate immunoglobulin secretion: role of bone marrow stromal cells and interleukin 6Q68036503
Human B lymphocytes define an alternative mechanism of adhesion to fibronectin. The interaction of the alpha 4 beta 1 integrin with the LHGPEILDVPST sequence of the type III connecting segment is sufficient to promote cell attachmentQ68416148
Human B lymphocytes capable of spontaneous Ig production in short-term cultures: characterization in the circulation and lymphoid tissuesQ68803352
The isolation of B lymphocytes from human peripheral blood using antibodies coupled to paramagnetic particles and rosetting techniquesQ69550656
Human recombinant IL-3 stimulates B cell differentiationQ69736165
Dual role of fibronectin in hematopoietic differentiationQ69935852
Human in vivo-induced spontaneous IgG-secreting cells from tonsil, blood and bone marrow exhibit different phenotype and functional level of maturationQ70163405
Quantitation of antibody production in mouse bone marrow during the secondary response to sheep erythrocytesQ70219315
Extracellular matrix production by the adherent cells of long-term murine bone marrow culturesQ70425630
Disorders of regulatory T cells in patients with selective IgA deficiency and its relationship to associated autoimmune phenomenaQ72767067
NK and T cell subsets regulate antibody production by human in vivo antigen-induced lymphoblastoid B cellsQ72802542
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectbone marrowQ546523
bone marrow cellsQ66004840
P304page(s)1739–1747
P577publication date1992-06-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleVLA-4-fibronectin interaction is required for the terminal differentiation of human bone marrow cells capable of spontaneous and high rate immunoglobulin secretion
P478volume175

Reverse relations

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